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Motion optimized conformal microwave imaging for biomedical applications / by Neil R. Epstein.

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Author	Epstein, Neil R.
Title	Motion optimized conformal microwave imaging for biomedical applications / by Neil R. Epstein.
Date	2013
Abstract	Investigations into alternative breast cancer (BC) imaging techniques have become increasingly popular based on the limitations of traditional imaging modalities: X-ray mammography uses ionizing radiation, has limited intrinsic contrast and is associated with high false-positive and false-negative rates. Microwave tomographic imaging (MTI) has the ability to detect a wide range of dielectric property (DP) values, and due to the contrast that exists between the DPs of normal and abnormal breast tissue. MTI has shown promise as an alternative BC imaging modality. This thesis reports on a third generation system currently used in clinical trials at Dartmouth Hitchcock Medical Center. This system's improvements include increased data acquisition speeds and capabilities due to upgraded microwave electronic components and motion control hardware, respectively. Part I of this work will evaluate the system's microwave electronics in terms of channel isolation, system sensitivity and measurement repeatability in an effort to define an optimal operational bandwidth. The system's antenna array is composed of two interwoven sub-arrays (SAs) that can independently move to a number of positions. We have found that incorporating measurement data obtained at larger SA separation spacing during 3D acquisition results in unwanted artifacts in the reconstructed images. S-parameter studies have indicated that signals transmitted at these larger separation distances fall below the noise floor (NF) of the system's receiving channels. Part II of this thesis will focus on analyzing measurement sensitivity as a function of increasing SA spacing. The analysis has resulted in the creation of a motion optimized imaging system increasing examination speeds by eliminating measurements positions where signals fall below the NF. Additionally, we have seen that our reconstruction algorithm has benefited from the incorporation of boundary information regarding the object under test (OUT). An optical-scanning system that can capture the boundar
Description	xxiv, 190 leaves : ill. (some col.) 28 cm.
Format	application/pdf
Advisor	Paul M. Meaney, Keith D. Paulsen, Alex Hartov, Mikael Persson
College	Thayer School of Engineering.
Issuing Body	Dartmouth Dissertations are made available through the Dartmouth Digital Library.
Degree	Thesis (Ph.D.)--Dartmouth College.
Copyright	All rights reserved. No part of this book may be reproduced in any form by any electronic or mechanical means without permission in writing from the author.
DOI	http://dx.doi.org/10.1349/ddlp.956

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