Cupredoxins, such as stellacyanin, plastocyanin, amicyanin, rusticyanin, and azurin perform electron transfer (ET) reactions with partner protein(s) in the cell. The role of the redox cofactor in these proteins is played by a copper ion, which...
Medical care -- Decision making. Health attitudes. Prostate -- Cancer -- Treatment -- Decision making. Prostate -- Cancer -- Patients -- Attitudes. Uncertainty. Video recording in medicine.
This dissertation used two studies to evaluate the appropriateness of a theoretical model exploring the relationships between screening/treatment beliefs and intending to be screened or treated for prostate cancer (P-CA). Study One examined...
Part I. A photoprecursor for difluorocarbene . The goal of this research was to develop a more practical and efficient photoprecursor for difluorocarbene. The first approach was concerned with the synthesis of 4,4-difluoropyrazoline-3,5-dione ( 5...
Flexible fiber scopes are widely used in industry and medicine. Typical scopes are made using conventional optical components and order-packed flexible image bundles. The optical performance of a flexible scope is largely determined by that of the...
Protein complexes play vital roles in cellular processes within living organisms. They are formed by interactions between either different proteins (hetero-oligomers) or identical proteins (homo-oligomers). In order to understand the functions of...
This thesis comprises two separate but related studies, dealing with two strongly interacting nanoscale systems on the border between the quantum and classical domains. In Part 1, we use a Born-Markov approximated master equation approach to study...
Oligomers -- Structure -- Mathematical models. Nuclear magnetic resonance spectroscopy.
Medical Term: Nuclear Magnetic Resonance, Biomolecular.
Protein complexes play vital roles in the fundamental processes of life. In particular, homo-oligomers are involved in cell signaling, regulation, and transport. To make detailed studies of these symmetric proteins, they need to be discovered, and...
This project focuses on the development of research tools and methods that are used to study the relationship between neural activity and subsequent hemodynamic responses in the human brain. This relationship, referred to as neurovascular coupling,...
Prior to biological conversion of lignocellulosic biomass, natural barriers to efficient enzymatic hydrolysis must be overcome, and a few pretreatment technologies effectively accomplish this job with chemicals. Although several factors are...
The main theme of this thesis is to investigate the origins of photosensitizer pharmacokinetic variability, how this pharmacokinetic variation affects photodynamic therapy (PDT), and to search for innovative strategies to reduce the...
The accelerated expansion of space in the Universe has been known for two decades. However, finding a plausible theory that describes this expansion is more difficult: Taking general relativity for granted requires us to stipulate the existence of...
This thesis focuses on the emergence of universal dynamical scaling in quantum critical spin systems driven out of equilibrium, with emphasis on quench dynamics which involves isolated standard critical points, multi-critical points, and...
Eddy currents (Electric) -- Mathematical models. Electric generators -- Windings. Finite element method.
Magnetic components, such as transformers and inductors, are essential parts of most power electronics circuits. They usually are the largest components in the circuit, and also account for a large portion of the power loss. Reducing the volume of...
For a local field K, we study the affine buildings Ξ n and Δ n naturally associated to SL n ( K ) and Sp n ( K ), respectively. Since Sp n ( K ) is a subgroup of SL 2 n ( K ), we investigate properties of a natural embedding of Δ n in Ξ 2 n ....
In an undercooled environment any protuberance or bump on a planar solid/liquid interface that extends into the melt enhances its growth since the surrounding temperature gradient is greater than that about the planar surface. Consequently, the...
Magnetic resonance imaging. ; Nuclear magnetic resonance.
Diffusion-weighted magnetic resonance imaging (MRI) provides unique contrast reflecting the translational motion of water in its microscopic environment. This imaging modality has been shown to highlight infarcted regions within minutes after an...
Gene set testing has become a critical tool for interpreting the results of high-throughput genomic experiments. Despite the development of robust statistical methods and extensive gene set collections, however, the results from gene set testing...
For ordinary knots in R 3 , there are no degree one Vassiliev invariants. For virtual knots, however, the space of degree one Vassiliev invariants is infinite dimensional. We introduce a sequence of three degree one Vassiliev invariants of virtual...
'The control of waves using periodic structures is crucial for modern optical, electromagnetic and acoustic devices such as diffraction gratings, filters, photonic crystals, solar cells, sensors, and absorbers. We present a high-order accurate...
In Chapter 2 we look at the distribution of permutation statistics in the context of pattern-avoiding permutations. The first part of this chapter deals with a recursively defined bijection of Robertson [37] between 123- and 132-avoiding...
Despite great progress in object recognition techniques, there is a mismatch between traditional approaches and the characteristics of real world vision tasks. We highlight in particular, three closely related areas of mismatch: i) recognition...
Microwave spectroscopy. Imaging systems -- Design and construction. Diagnostic imaging -- Digital techniques. Breast -- Cancer -- Diagnosis. Microwave imaging in medicine.
Microwave spectroscopy has been investigated as a possible modality for breast imaging because of the significant contrast in electrical properties between normal and malignant tissue over the microwave spectrum. A liquid-coupled, non-contacting...
The opportunistic pathogen Pseudomonas aeruginosa secretes a protein that triggers the accelerated degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) in airway epithelial cells. This protein, known as the CFTR inhibitory...