Arabidopsis thaliana -- Genetics. Transcription factors. Iron -- Metabolism. Iron deficiency diseases in plants -- Genetic aspects.
In order to preserve a balance between the requirement for iron and its toxicity, plants likely maintain tight control over iron homeostasis. We are interested in identifying factors involved in the regulation of iron uptake and have examined this...
Manifolds (Mathematics) Geodesics (Mathematics) Space and time.
We investigate weak and strong refocusing of light rays in a space-time and related concepts. A strongly causal space-time ( X^ n +1 , g ) is emphstrongly refocusing at x ∈ X if there is a point y ≠ x such that all null-geodesics through y pass...
B cells -- Tumors. ; Cancer -- Immunotherapy. ; T cells. ; CD antigens.
The indolent B-cell malignancies of lymphoma and myeloma account for a great number of adult cancers in the United States annually. Hi-dose combination chemotherapy, bone marrow transplants and monoclonal antibody therapeutics have improved the...
Little is known about the emergence of life from nonliving precursors. A key missing- piece is the origin of homochirality: nearly all life is characterized by exclusively dextrorotary sugars and levorotary amino acids. The research presented in...
Networks that model relationships in the real world have attracted much attention in the past few years. The "link prediction problem" plays a central role in the network area. In this thesis, we explore the link prediction problem in a...
Flexible fiber scopes are widely used in industry and medicine. Typical scopes are made using conventional optical components and order-packed flexible image bundles. The optical performance of a flexible scope is largely determined by that of the...
Community health services -- United States -- Evaluation. ; Health care reform -- United States. ; Medical care -- United States -- Evaluation. ; Evidence-based medicine.
Second harmonic generation. ; Second harmonic generation -- Mathematical models. ; Glass -- Effect of infrared radiation on. ; Glass -- Electric properties.
The processes by which nonlinear physical systems approach thermal equilibrium is of great importance in many areas of science. Central to this is the mechanism by which energy is transferred between the many degrees of freedom comprising these...
Antennas (Electronics); ; Thermotherapy. ; Cancer -- Treatment.
Engineers have devised many techniques by which to raise the temperature of a cancer tumor 8 degrees above body temperature. Such treatment is called hyperthermia; experiments in vitro suggest it may be an effective adjunct to standard radition...
Gene set testing has become a critical tool for interpreting the results of high-throughput genomic experiments. Despite the development of robust statistical methods and extensive gene set collections, however, the results from gene set testing...
Magnetic resonance imaging. ; Nuclear magnetic resonance.
Diffusion-weighted magnetic resonance imaging (MRI) provides unique contrast reflecting the translational motion of water in its microscopic environment. This imaging modality has been shown to highlight infarcted regions within minutes after an...
Stark-geometry photorefractive multiple quantum well (PR-MQW) spatial light modulators (SLMs) show promise for several optoelectronic applications such as high-speed image correlation and real-time 3-D holographic imaging. Their performance is...
Recent years have witnessed a new class of monitoring applications that need to continuously collect information from remote data sources. Those data sources, such as web click-streams, stock quotes, and sensor data, are often characterized as...
Leukemia represents a small percentage of human cancer, accounting for about 5% of all cases of cancer in adults, but, interestingly, for about 50% of all cases of cancer in children. The behavior of leukemia is often regulated by the chromosomal...
At the heart of computer games and computer generated films lies 3D content creation. A student wanting to learn how to create and edit 3D meshes can quickly find thousands of videos explaining the workflow process. These videos are a popular...
Solar (Computer architecture). ; Ubiquitous computing. Sensor networks. ; Detectors. ; User interfaces (Computer systems).
The complexity of developing context-aware pervasive-computing applications calls for distributed software infrastructures that assist applications to collect, aggregate, and disseminate contextual data. In this dissertation, we present a Context...
In this thesis we look at several problems that lie in the intersection between combinatorial and multiplicative number theory. A common theme of many of these problems are estimates for and properties of the smooth numbers, those integers not...
The accelerated expansion of space in the Universe has been known for two decades. However, finding a plausible theory that describes this expansion is more difficult: Taking general relativity for granted requires us to stipulate the existence of...
In this thesis we develop a theory of Fourier analysis and fast Fourier transforms (FFTs) for finite inverse semigroups. Our results generalize results in the theory of Fourier analysis for finite groups. There is a general method for generating...
The ionosphere is the primary source for heavy ions which are ubiquitous in the terrestrial magnetosphere. Low-altitude energization in the auroral ionosphere results in bulk heating and transverse acceleration of ions, which begin to upwell and/or...
We present new appearance editing algorithms that allow artists to perform complex editing operations on spatially-varying appearance datasets such as images and measured materials, in an intuitive and efficient manner. The goal is to develop...
Relativity (Physics). ; Anisotropy -- Mathematical models. ; Einstein field equations. ; Newtonian fluids. ; Astrophysics.
We study the effects of anisotropic pressure on the properties of spherically symmetric, gravitationally bound spheres. We consider the full general-relativistic and Newtonian treatment of this problem and obtain exact solutions for various forms...
Near infrared spectroscopy -- Instruments -- Design and construction.;""Magnetic resonance imaging -- Instruments -- Design and construction."";""Breast -- Cancer -- Imaging."";""Breast -- Magnetic resonance imaging."";""Breast -- Cancer --...
As the ubiquitous complexity of common disease has become apparent, so has the need for novel tools and strategies that can accommodate complex patterns of association. In particular, the analytic challenges posed by the phenomena known as...
This thesis contains material relating to two separate subjects. The first section determines when the C*-algebra affiliated to a directed graph has continuous trace. We use groupoid methods and the focus is on producing conditions on a graph that...
Ultra-high molecular weight polyethylene (UHMWPE) remains the most common bearing material for total joint arthroplasty. Advances in radiation cross-linking and other post-consolidation treatments have led to a rapid differentiation of polyethylene...
This thesis presents two-fluid simulations of forced magnetic reconnection with finite electron inertia in two and three dimensional periodic systems. Reconnection in the system is driven by a spatially localized forcing function, added to the ion...
Robustness to genetic perturbations is a fundamental property of all living things. The genetic code is degenerate, RNA secondary structure is robust to sequence changes, and protein structure is robust to amino acid substitutions. Complex systems...
Magnetic fields at all scales are prevalent in our universe. However, current cosmological models predict that initially the universe was bereft of large-scale fields. Standard magnetohydrodynamics (MHD) does not permit magnetogenesis; in the MHD...
Apoptosis is induced by chemicals and death receptor activation. Although the stimuli are different, common proteins are activated downstream. The Bcl-2 family of proteins plays an important role in mediating apoptotic signaling at the mitochondria...
Mitomycin C -- Genetic aspects. ; DNA damage. ; Drug resistance in cancer cells. ; Cancer -- Chemotherapy -- Genetic aspects.
Our laboratory is concerned whether the distribution of chemically-induced DNA damage is non-random at the level of individual genes. Using changes in gene expression as a marker for DNA damage, we have previously demonstrated that genotoxic...
Structural control (Engineering). ; Smart structures -- Vibration. ; Strains and stresses -- Computer simulation. ; Automatic control -- Sensitivity. ; Feedback control systems.
This thesis investigates vibration-based damage identification problems in smart structures. Vibration-based damage metrics suffer from small sensitivity of modal properties to damage, thus making it difficult to detect, locate, and determine the...
Two-phase flow -- Mathematical models. ; Gas dynamics -- Mathematical models. ; Kinetic theory of gases.
The kinetic theory based gas-dynamical computational method, due to (Prendergast and Xu, 1993: Xu and Prendergast, 1994) is generalized to two-phase flow computations. The Bhatnagar-Gross-Krook kinetic model is generalized to the case of two...
Many of today's communication and imaging technologies share the common challenge of signal deterioration due to water's large absorption coefficient. As an example, it is water molecules that contaminate the fused silica of optical fibers and...
Evolutionary Computation (EC) is one of the most advanced computational techniques. It has been frequently and successfully used to find good solutions to many complicated optimization problems with limited computational resources. EC is the...
For a long-lived metastable system, the decay of the survival probability is typically exponential. However, deviations are known to exist at short times (the quantum Zeno effect) and at long times (algebraic tails in classical hydrodynamic...
Scleroderma (systemic sclerosis; SSc) is a devastating autoimmune disease of unknown etiology for which there is no cure, and no truly effective therapies available. Immune dysfunction, fibrosis and vasculopathy are the three major features of the...
Since alkoxyamines, O-alkylated nitroxide derivatives, are important control agents for nitroxide-mediated polymerization, protocols for their synthesis should be straigh- forward, cost-effective, and versatile. We have utilized a facile method for...