Chapter one: Synthesis, resolution and application of P-chirogenic phosphines. This chapter serves as a general introduction, and gives a brief overview of the synthesis, resolution and applications of chiral organophosphorus compounds. In...
Scientific methods that detect deception have been studied since 1895. Among them, computational methods have gained popularity in recent decades thanks to the development of artificial intelligence, (AI). Detecting deception by categorizing...
The field of proteomics aims to identify and quantify the protein contents of a biological sample. The mass spectrometer is the instrument of choice to characterize these proteins. In the typical proteomics experiment, mass spectra are collected...
Indole alkaloids -- Synthesis. Ring formation (Chemistry). Radicals (Chemistry).
A novel radical cyclization of 2-bromoindoles was examined, generating a series of hexahydropyrrolo[3,4- b ]indoles in fair yield. This process involved the generation of a variety of indole-3-carboxamides followed by the introduction of bromine at...
The present thesis is focused on developing a better understanding of factors driving disease biology and overall risk using cancers of the bladder and breast as model systems. As no single approach was likely to unravel the complexities of these...
Hyperthermia, the elevation of tissue temperature from 42°C to 50°C, is currently being investigated as an adjunct to radiation therapy in the treatment of cancer. The interstitial microwave antenna array hyperthermia (IMAAH) system is designed...