Library Staff (Formal Group Photos); Identifications: 1. Monique C. Cleland; 2. Michael J. Lach; 3. Donald L. Saporito; 4. Molly M. O'Connor; 5. Theresa Blake; 6. Stanley Brown; 7. William B. Meredith; 8. Edward Connery Lathem; 9. June I. Hicks;...
Microwave spectroscopy. Imaging systems -- Design and construction. Diagnostic imaging -- Digital techniques. Breast -- Cancer -- Diagnosis. Microwave imaging in medicine.
Microwave spectroscopy has been investigated as a possible modality for breast imaging because of the significant contrast in electrical properties between normal and malignant tissue over the microwave spectrum. A liquid-coupled, non-contacting...
Medical care -- Decision making. Health attitudes. Prostate -- Cancer -- Treatment -- Decision making. Prostate -- Cancer -- Patients -- Attitudes. Uncertainty. Video recording in medicine.
This dissertation used two studies to evaluate the appropriateness of a theoretical model exploring the relationships between screening/treatment beliefs and intending to be screened or treated for prostate cancer (P-CA). Study One examined...
A sample of 46 previously unidentified, intermediate- to high-redshift, near-infrared (NIR)-selected galaxy clusters have been discovered in the Andromeda catalog of the Oxford Dartmouth Thirty Degree Survey (ODTS). These clusters vary from low- to...
The great strength of the C-F bond has enabled fluorocarbons to find many industrial and domestic applications, and makes C-F activation a chemical and technical challenge akin to that of C-H bond activation in hydrocarbons. In our mission to...
Previous studies have shown that the mucosal immune system is present in the female reproductive tract and under hormonal control. With the recognition that underlying stromal cells regulate epithelial cell function and hormonal responsiveness,...
Free electron lasers -- Experiments. Wave guides -- Design and construction. Diffraction gratings -- Experiments. Electron beams. Infrared sources.
The far infrared region of the electromagnetic spectrum, 15-3000 μm in wavelength, has a paucity of narrow band laser sources. To address the issue of whether a grating based free electron laser could operate well as such a source, a grating...
Tetrapyrroles -- Synthesis. Tetrapyrroles -- Mechanism of action. Transition metal catalysts.
Previous studies have shown that the mucosal immune system is present in the female reproductive tract and under hormonal control. With the recognition that underlying stromal cells regulate epithelial cell function and hormonal responsiveness,...
Spatial heterogeneity inherent in ecological systems impacts both diversity and community structure. However, little is known about the influence of habitat heterogeneity on temporal variability in communities. I performed several studies to...
Indole alkaloids -- Synthesis. Ring formation (Chemistry). Radicals (Chemistry).
A novel radical cyclization of 2-bromoindoles was examined, generating a series of hexahydropyrrolo[3,4- b ]indoles in fair yield. This process involved the generation of a variety of indole-3-carboxamides followed by the introduction of bromine at...
Recent studies demonstrating that eye position modulates auditory responses in a brainstem auditory structure and in primary auditory cortex (Groh et al., 2001; Werner-Reiss et al., 2003a), suggest preparation of the auditory signal for eventual...
This thesis considers the two special sensor networks for future sensor network design: mobile sensor networks and hybrid network of sensors and robots. To investigate two types of networks, we abstract two most important aspects that are ingrained...
Sorting very large datasets is a key subroutine in almost any application that is built on top of a large database. Two ways to sort out-of-core data dominate the literature: merging-based algorithms and partitioning-based algorithms. Within these...
Recombinant protein production has traditionally relied on organisms with well developed molecular biological tools, such as E. coli. However, E. coli is not suited for large industrial scale production due to its propensity to produce organic...
Naturally occurring macrocyclic tetrapyrroles of the chlorin and bacteriochlorin classes play important roles in essential biological processes, including photosynthesis and nitrogen cycling. The chromophores also show promise in various...
Atlantic salmon -- Growth. Atlantic salmon -- Effect of predation on -- Connecticut River Watershed. Atlantic salmon -- Mortality -- Connecticut River Watershed. Fish populations. Atlantic salmon -- Toxicology -- Connecticut River Watershed. Cottus...
Juvenile, stream-dwelling salmon are a model system for studies of density dependence. However, while salmon exhibit diverse mechanisms and patterns of density dependence, the factors that drive variation in density dependence are not clear. I used...
Optical tomography. Fluorescence. Imaging systems -- Design and construction. Diagnostic imaging -- Mathematical models. Brain -- Diseases -- Diagnosis. Brain -- Magnetic resonance imaging.
Fluorescent molecules targeted to reveal information on tissue function have been used as research tools in ex vivo and subsurface characterization of diseased tissue for years. Exploiting this specificity for in vivo imaging through centimeters of...
Renewable energy sources are becoming increasingly important as sustainable alternatives to fossil fuels. One of these renewable sources, cellulosic biomass, is a relatively inexpensive and abundant resource that can be converted into liquid fuels...
This thesis presents two-fluid simulations of forced magnetic reconnection with finite electron inertia in two and three dimensional periodic systems. Reconnection in the system is driven by a spatially localized forcing function, added to the ion...
The coordination and coupling of the several steps in mRNA biogenesis helps to ensure proper regulation of gene expression. The DEAD-box helicase Dbp5/Rat8 is an essential mRNA export factor that has also been implicated in other steps of mRNA...
Wireless communication systems. Computer network protocols.
We evaluate mobility predictors in wireless networks. Handoff prediction in wireless networks has long been considered as a mechanism to improve the quality of service provided to mobile wireless users. Most prior studies, however, were based on...
The objective of this thesis was to examine the neural and physiological substrates underlying the processing of aversive information, and how individual differences in anxiety influence these responses. In a series of experiments, we utilized skin...
The Euler '-function and Carmichael -function are extremely important in modern number theory, and much work has been devoted to studying the distribution and arithmetic properties of the values of each function. One interesting unresolved question...
Electric generators -- Windings. Electric inductors -- Design and construction -- Mathematical models. Electric current converters -- Design and construction -- Mathematical models. Energy dissipation -- Mathematical models.
Magnetic components for high-frequency power conversion applications can have significant losses that compromise the performance of the converter. In particular, winding losses can be large due to high-frequency effects that are difficult to model...
GABA -- Receptors. Anabolic steroids -- Physiological effect. Androgens -- Physiological effect. Prosencephalon. Neurotransmitters -- Effect of drugs on. Psychoneuroendocrinology.
Anabolic androgenic steroids (AAS) are derivatives of testosterone originally designed for therapeutic applications to enhance anabolic potency (protein synthesis and muscle growth) while exerting low androgenic (masculinizing) effects. The...
Nutrients play fundamental roles in biological systems, affecting plant growth and quality, community structure, and species interactions. Although the effects of nutrients on primary and secondary production have been well documented, their...
I investigate the kinematics and space densities of the local cataclysmic variable (CV) population. CVs are close binary star systems composed of a white dwarf that accretes matter from a less compact companion star in Roche lobe overflow....
Aneuploidy is the leading cause of pregnancy loss and birth defects in humans. At least 5% of all recognized pregnancies are aneuploid. Maternal meiosis is especially error-prone and the rate of chromosome missegregation increases exponentially...
In this thesis we develop a theory of Fourier analysis and fast Fourier transforms (FFTs) for finite inverse semigroups. Our results generalize results in the theory of Fourier analysis for finite groups. There is a general method for generating...
Earlier in our laboratory, a facile synthesis of the 2- and 3-nitroindoles was realized. These compounds showed promise as powerful intermediates in the synthesis of novel structures and natural products. The reactivity of 2- and 3-nitroindoles...
Phospholipase C -- Mechanism of action. Retinal degeneration -- Pathophysiology. Retinal degeneration -- Genetic aspects. Endocytosis. Rhodopsin. Cellular signal transduction. Light -- Physiological effect. Arrestin. Clathrin. Adaptor Proteins
Mutations in the Drosophila retinal-specific Phospholipase C (NORPA) cause massive retinal degeneration within five days of constant light exposure. We have previously shown that in norpA mutants persistent complexes between the light receptor...
DC-to-DC converters -- Design and construction. Electric inductors -- Design and construction. Thin film devices -- Design and construction. Microprocessors -- Power supply. Microfabrication. Transients (Dynamics).
This work studied the effects of silt-sized particles on the mechanical properties and microstructures of laboratory-grown granular ice from -20°C to -2°C. Experimental findings show that such particles significantly affect the...
An efficient synthetic approach to both 2-acyl-1-(substituted)indoles and 2-nitro-1-(substituted)indoles by reaction of 2-lithio-1-(substituted)indoles with appropriate electrophiles is presented. Inverse quenching of 2-lithioindoles 5 and 208 with...
Part I. A photoprecursor for difluorocarbene . The goal of this research was to develop a more practical and efficient photoprecursor for difluorocarbene. The first approach was concerned with the synthesis of 4,4-difluoropyrazoline-3,5-dione ( 5...
This thesis presents technologies for the design, fabrication, operation, and control of electrostatic MEMS micro-robots. It describes prototype micro-robots, with dimensions of 60 μm by 250 μm by 10 μm, that are capable of controllable...
Three-dimensional imaging in medicine -- Mathematical models. Intraoperative monitoring. Cerebral cortex -- Imaging. Computer vision. Space perception.
Brain deformation models have proven to be a powerful tool in compensating for soft tissue deformation during image-guided neurosurgery. The accuracy of these models can be improved by incorporating intraoperative measurements of brain motion. We...
Brain -- Tomography. Magnetic resonance imaging -- Brain. Near infrared spectroscopy. Image processing -- Digital techniques.
Diffuse optical tomography (DOT) using near infrared (NIR) light has become a promising modality because it has the capability to non-invasively quantify oxygen saturation and hemoglobin content with potentially high temporal resolution and...
The synthesis of macrocyclic tetrapyrroles continues to be an area of vigorous research due to their application to a wide range of fields spanning the physical sciences. Only recently have general syntheses for the reduced systems, such as...
Prion diseases are infectious neurodegenerative disorders characterized by a conformational change of the host-encoded prion protein. The normal nonpathogenic isoform of the prion protein (PrPc) is primarily composed of α-helices and very low...
This thesis characterized the solubilities of sugar monomers and xylooligomers in water and explored the potential role of solubility for pretreatment of cellulosic Biomass by hemicellulose hydrolysis in only water. A novel apparatus was developed...
Identifying and understanding sources of individual variation in fecundity is of central importance to life history theory and population ecology. In this study, I first examined how factors on the breeding grounds in eastern Maryland affected the...
The irreversible destruction of the tissues that comprise synovial joints is the hallmark of both rheumatoid arthritis and osteoarthritis. In both diseases, inflammatory cytokines, such as interleukin-1β, stimulate the production of matrix...
Hand -- Psychophysiology. Conditioned response. Hand -- Movements. Perceptual-motor processes.
The present studies examine the flexible application of two stimulus-response (SR) mappings to a single set of stimuli. The following questions are addressed: (1) Can dual mapping performance equal single mapping performance (2) Can rapid map...