The completion of the Human Genome Project in 2003 and the HapMap Project in 2005 has broadened the spectrum of genetic research tools that allow researchers to conduct genome-wide association studies (GWAS) for detecting genetic variants that...
Earlier in our laboratory, a facile synthesis of the 2- and 3-nitroindoles was realized. These compounds showed promise as powerful intermediates in the synthesis of novel structures and natural products. The reactivity of 2- and 3-nitroindoles...
Primary care (Medicine) -- United States -- Evaluation. ; Medicine -- Specialties and specialists. ; Physicians -- Supply and demand -- United States.
Background. Strengthening the role of primary care is considered a key element in improving the outcomes and efficiency of health care delivery. Previous studies of the benefits of primary care have primarily examined the association of primary...
Free electron lasers -- Experiments. Wave guides -- Design and construction. Diffraction gratings -- Experiments. Electron beams. Infrared sources.
The far infrared region of the electromagnetic spectrum, 15-3000 μm in wavelength, has a paucity of narrow band laser sources. To address the issue of whether a grating based free electron laser could operate well as such a source, a grating...
This dissertation details the use of a new catalog of Galactic bulge field RR Lyrae variables to advance the understanding of the structure of the Milky Way Galaxy. The catalog contains 3667 RR0 Lyrae stars from the eight-year MACHO Project...
Primary care (Medicine) -- United States -- Evaluation.
Medicine -- Specialties and specialists.
Physicians -- Supply and demand -- United States.
Background: Strengthening the role of primary care is considered a key element in improving the outcomes and efficiency of health care delivery. Previous studies of the benefits of primary care have primarily examined the association of primary...
Modifiable Factor Relationships with Biopsychosocial Disability in Multiple Sclerosis
Brant J. Oliver
Problem Statement: Multiple sclerosis (MS) is a chronic disease of the central nervous system and is among the most common neurological...
Signs: Canada, Canary Islands, Costa Rica, El Salvador, Europe, French Polynesia, Guatemala, Honduras, Iceland, Indonesia, Italy, Japan, Mexico, Nicaragua, Tanzania.
Signs: Canada, Canary Islands, Costa Rica, El Salvador, Europe, French Polynesia, Guatemala, Honduras, Iceland, Indonesia, Italy, Japan, Mexico, Nicaragua, Tanzania.
Chapter 1: Munchnones and mesoionic heterocycles The reactivity, regioselectivity, and synthetic applications of munchnones (1,3-oxazolium-5-olates) is a common theme which runs through Chapters 2-5. The definition, structure, and reactivity of...
While anthropogenic emissions of the toxic element mercury (Hg) to the atmosphere are currently rising, major uncertainties remain in determining the relative impacts of anthropogenic activity and natural processes on the global Hg cycle. In this...
Temperature has powerful effects on all scales of biological organization from biochemical reactions to ecosystem processes. Despite the well-appreciated influence and thorough understanding of the physiological and population consequences of...
Epilepsy is associated with cognitive impairments which often manifest as a higher prevalence of memory impairments. Memory impairments in patients with epilepsy may persist even with sufficient control of seizures, suggesting other factors may...
Wireless communication systems. Computer network protocols.
We evaluate mobility predictors in wireless networks. Handoff prediction in wireless networks has long been considered as a mechanism to improve the quality of service provided to mobile wireless users. Most prior studies, however, were based on...
In the nervous system, neuronal communication relies critically on the function of membrane ion channels. One of these is the voltage-gated sodium channel (VGSC), which is essential for the generation and propagation of action potentials in...
G protein coupled receptors (GPCRs) make up somewhere between 30-50% of all current drug targets, yet the structural characterization of these receptors has been moderate at best. Until recently, structural data were almost nonexistent and...
Black-throated blue warbler -- Habitat. Black-throated blue warbler -- Behavior. Black-throated blue warbler -- Food. Black-throated blue warbler -- Nests.
Hematopoietic stem cells (HSCs) are the cells that can give rise to all different lineages of differentiated/mature blood cells. HSCs are capable of self-renewal and maintaining the homeostasis of differentiated cells for specific functions. The...
Nutrients play fundamental roles in biological systems, affecting plant growth and quality, community structure, and species interactions. Although the effects of nutrients on primary and secondary production have been well documented, their...
A double-acceleration stage linear time of flight mass spectrometer (TOF MS) with Nd/YAG laser ablation cluster source was designed and constructed for cluster production, study and deposition. Cumulenic polycarbons SC n S ( n = 2-27) were...
Regulatory linkage between epibiotic organisms and their host zooplankton populations is one of the least understood topics in zooplankton biology, despite the likely importance of epibionts to pelagic communities. These laboratory studies with...
Arsenic is implicated in numerous human pathologies, including cancer and several forms of liver disease. One contributing mechanism may involve alterations of CYP levels by arsenic. CYP3As are the most abundant CYP proteins in human liver and...
During an immune reaction to an invading pathogen, a population of lymphocytes with receptors that specifically recognize the pathogen are activated and become memory cells. Characteristically, memory lymphocytes persist for long periods of time...