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Alumni Luncheon June 17 1950 for eight reunion classes Alumni Magazine July 1950; please return to Dartmouth News Service Hanover NH
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The role of chromatin regulation in gene expression: analyzed through the phenotype characterization of Chd6 ATPase-/- mice and methylation status of the human globin locus.
Chromatin -- Structure. DNA -- Methylation. Globin genes -- Expression. Adenosine triphosphatase. Proteins -- Chemical modification.
Epigenetic regulation of gene expression is a developing field of study with many potential therapeutic applications. Chromatin remodeling is necessary for proper mammalian development, and misregulation of this process is associated with many...
Dartmouth Dissertations

Specificity in signaling : bacterial decision-making through the cyclic diguanylate second messenger / by Kurt M. Dahlstrom
Cyclic diguanylate (c-di-GMP) is a primarily bacterial and nearly universal second messenger used to stimulate a variety of responses from the cell by binding effector proteins. It is created by enzymes called diguanylate cyclases (DGCs) and broken...
Dartmouth Dissertations

Transgenic cyclin E murine models as discovery tools for lung cancer biology, therapy, and prevention.
Lungs -- Cancer -- Genetic aspects. ; Cyclins -- Pathophysiology. ; Transgenic mice. ; Pharmacogenomics. ; Cyclin E -- genetics.
Dartmouth Dissertations

Electron transfer reaction in solution: initial charge separation distance distribution and its impact on free ion formation.
Free radicals (Chemistry). ; Electron donor-acceptor complexes. ; Ions.
In this study, the initial charge separation distance and its impact on free radical ion (FRI) formation are investigated in detail. Transient photocurrent techniques together with other spectroscopic methods were used with a series of donors and...
Dartmouth Dissertations

Palladium-catalyzed asymmetric phosphination: stereochemical and mechanistic studies.
Asymmetric synthesis. ; Palladium catalysts. ; Phosphine. ; Organophosphorus compounds -- Synthesis. ; Stereochemistry.
Chapter one: Synthesis, resolution and application of P-chirogenic phosphines. This chapter serves as a general introduction, and gives a brief overview of the synthesis, resolution and applications of chiral organophosphorus compounds. In...
Dartmouth Dissertations

C₂-Symmetric Bis(phosphines) and Their Metal Complexes : Synthesis, Materials Application, and Screening Racemic Catalysts / Sanderson, Matthew David
Chapter 1: The dimethylation of the C2-symmetric Pt-phosphido complex Pt((R,R)-Me-DuPhos)(IsPCH2PIs) (Is = 2,4,6-(iPr)3C6H2) to yield rac- and meso- [Pt((R,R)-Me-DuPhos)(IsMePCH2PMeIs)][OTf]2 represents an interesting case of the Horeau principle...
Dartmouth Dissertations

Game-theoretic approaches for adversarial multi-armed bandit scenarios.
We pose several adversarial variants of the multi-armed bandit scenario and propose new approaches for their play and analysis. Our casino patron seeks to discover information about an unknown system as a means to long-term payoff -- exploration...
Dartmouth Dissertations

RR Lyrae stars as tracers of stellar populations in the Galactic bulge and satellite galaxies.
RR Lyrae stars. Milky Way. Stars -- Populations.
This dissertation details the use of a new catalog of Galactic bulge field RR Lyrae variables to advance the understanding of the structure of the Milky Way Galaxy. The catalog contains 3667 RR0 Lyrae stars from the eight-year MACHO Project...
Dartmouth Dissertations

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