Dartmouth Digital Library Program

Development and quantification of a 3D brain deformation model for model-updated image-guided stereotactic neurosurgery.
Three-dimensional imaging in medicine -- Mathematical models. ; Stereoencephalotomy.
In the past, clinicians skilled at image-guided neurosurgery have relied solely on pre-operative scans for their navigational information. Often in the course of surgery, tissue is purposely retracted/resected or inadvertently moved resulting in a...
Dartmouth Dissertations

Neo-architectonics computer-aided histological examination of the human visual cortex.
Visual cortex -- Imaging. ; Visual cortex -- Histology. ; Image processing -- Digital techniques.
Functional neuroimaging has confirmed a high degree of localization of function in the cerebral cortex of man. In contrast, microstructural analysis has contributed very little to the topographical characterization of cortical areas. In this work I...
Dartmouth Dissertations

Behavioral and neural investigations of behaviorally relevant features of auditory stimuli.
Auditory pathways -- Physiology. ; Auditory perception -- Physiological aspects. ; Directional hearing -- Physiological aspects. ; Speech perception -- Physiological aspects. ; Prefrontal cortex -- Physiology. ; Parietal lobes -- Physiology. ;...
Studies of the structure and function of the human and non-human primate auditory system have led to the hypothesis that it is composed of dorsal and ventral processing streams that are respectively dedicated to spatial and non-spatial processing....
Dartmouth Dissertations

Within and between hand acquisition of multiple stimulus-response mappings.
Hand -- Psychophysiology. Conditioned response. Hand -- Movements. Perceptual-motor processes.
The present studies examine the flexible application of two stimulus-response (SR) mappings to a single set of stimuli. The following questions are addressed: (1) Can dual mapping performance equal single mapping performance (2) Can rapid map...
Dartmouth Dissertations

The regulation and packaging of Cif, a novel virulence factor of Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen of humans and the leading cause of mortality in patients with the inherited disorder cystic fibrosis (CF). The focus of the studies presented herein was characterization of the regulation and...
Dartmouth Dissertations

Selective serotonergic modulation of cortical pyramidal neurons in the rodent prefrontal cortex / by Daniel Avesar.
Serotonin (5-hydroxytryptamine, 5-HT) in the prefrontal cortex (PFC) plays an important role in cognitive processing and emotional regulation, and altered serotonergic signaling in the cortex is associated with disorders such as schizophrenia,...
Dartmouth Dissertations

Individual differences in callosal organization: relationship to interhemispheric communication and hemispheric asymmetries.
Corpus callosum -- Physiology. Cerebral hemispheres. Laterality. Sensorimotor integration. Brain -- Localization of functions.
The overarching goal of the dissertation was to further understanding of the relationship between callosal organization, functional lateralization, and interhemispheric communication in the healthy, young adult brain. Three converging methodologies...
Dartmouth Dissertations

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