Intestine, Large -- Cancer -- Epidemiology. ; Intestine.
Colorectal cancer is the fourth most common cancer diagnosis and the second leading cause of cancer-related death in the United States. Most colorectal cancers are believed to develop from precursor lesions known as colorectal adenomas....
Congenital heart disease in children -- Surgery -- Evaluation. ; Heart -- Abnormalities -- Surgery -- Evaluation. ; Outcome assessment (Medical care).
Hypoplastic left heart syndrome (HLHS) is a heart malformation that requires surgical intervention for survival. Without surgery, 95% of neonates with HLHS die in the first month of life. Two surgical approaches are available, a series of...
Access control is a core component of any information-security strategy. Researchers have spent tremendous energy over the past forty years defining abstract access-control models and proving various properties about them. However, surprisingly...
Clinical medicine -- Decision making. ; Medical informatics. ; Patient participation. ; Osteoarthritis -- Treatment. ; Knee -- Diseases -- Treatment. ; Decision Making. ; Decision Support Techniques.
Problem Statement. Effective patients' decision aids (PtDAs) help patients understand clinical information and reduce decisional conflict. PtDAs that also explicitly provide guidance through four """"Deliberative Steps"""" may achieve additional...
Van Allen radiation belts -- Mathematical models. ; Magnetosphere -- Mathematical models. ; Magnetohydrodynamics -- Mathematical models.
The physics of geomagnetically-trapped radiation has been a topic of interest since the discovery of the Van Allen belts in 1958. As the energetic particles comprising these belts can pose a hazard to human activity in space, considerable effort...
Light scattering from tissue originates from the fluctuations in intra-cellular and extra-cellular components, so it is possible that macroscopic scattering spectroscopy could be used to quantify sub-microscopic structures. Both electron microscopy...
Magnetoencephalography -- Technique.; Magnetic susceptibility.
The measurement of human brain function is the goal of many noninvasive medical imaging modalities. Two sources of physiological contrast are commonly targeted to achieve this goal. The most direct approach to measuring neuronal activity is with...
For the most part, research on self-regulation has focused on behavior-control, which is how people self-regulate in the face of immediate urges and temptations (e.g., resisting cookies that are close at hand, or resisting beer that is being freely...
The demand for novel molecularly targeted drugs will continue to rise as we make progress toward personalizing cancer treatments to the molecular signatures of individual tumors. While the collection and analysis of genomic data has become routine,...
Protein phosphorylation is an important regulatory mechanism for the control of countless processes in living systems. The delicate management of phosphate attachment to, and removal from, serine, threonine and tyrosine residues in proteins...
In utero exposure to maternal malnutrition is associated with increase offspring susceptibility to cardiometabolic and neuropsychiatric disease. Epigenetic mechanisms mediate, at least in part, fetal adaptations to adverse in utero environments...
Proteins are ubiquitous in cells and are essential to a wide range of biological processes. Since existing proteins occupy only a small portion of the space of possible amino acid composition, understanding their sequence-structure-function...
Black-throated blue warbler -- Habitat. Black-throated blue warbler -- Behavior. Black-throated blue warbler -- Food. Black-throated blue warbler -- Nests.
Robots -- Control systems -- Design and construction. Mobile robots. Robots -- Dynamics.
This thesis examines the issues of vehicle and information dynamics in the control of a multi-robot system using a radial-basis potential function controller. Distributed control of multi-robot systems requires each robot to communicate state...
Perceptual-motor learning -- Physiological aspects. ; Language acquisition -- Physiological aspects. ; Motor ability -- Physiological aspects. ; Knots and splices.
The studies presented in this dissertation explore several points of intersection between action perception and production within the human brain. One's ability to use perceptual information about another individual's actions to guide and inform...
During an immune reaction to an invading pathogen, a population of lymphocytes with receptors that specifically recognize the pathogen are activated and become memory cells. Characteristically, memory lymphocytes persist for long periods of time...
Overweight persons -- Attitudes. ; People with disabilities -- Attitudes. ; Obesity -- Public opinion. ; Stigma (Social psychology). ; Self-presentation.
In the last few years, a new perspective on the management of obesity has emerged. Instead of focusing on dieting and weight loss efforts, the new approach focuses on size acceptance. The concept of positively accepting one's deviant features has...
Sponges are a historically ambiguous taxon, often considered primitively simple representatives of early Metazoa, living fossils from the era before the complex morphological features of the bilaterian phyla appeared in the Cambrian. Yet recent...
The great strength of the C-F bond has enabled fluorocarbons to find many industrial and domestic applications, and makes C-F activation a chemical and technical challenge akin to that of C-H bond activation in hydrocarbons. In our mission to...
T cells. T cells -- Receptors. CD antigens. CD4 antigen. Immunologic memory. Herpesvirus diseases -- Immunological aspects. Vaccinia. CD8-Positive T-Lymphocytes -- immunology. CD4-Positive T-Lymphocytes -- immunology. Herpesviridae Infections --...
The phenomenon of immunological memory has been known for thousands of years. This knowledge has been applied to vaccination, which has resulted in a dramatic reduction in the number of deaths due to infectious diseases. Immunological memory is...
Antibodies are known to be a primary correlate of protection in almost all current vaccines, and thus evaluating the antibody response is of critical importance in attempting to predict the efficacy of novel vaccine candidates. Historically...
For most cancers, the genetic mechanisms that predispose normal cells to neoplastic transformation and tumor cells to therapeutic eradication are poorly understood. High throughput genotyping technologies have allowed the rapid discovery of...
Prostate cancer (PCa) recurrences are often predicted by assessing the status of surgical margins (SM) – positive surgical margins (PSM) increase the chances of biochemical recurrence by 2-4 times which may lead to PCa recurrence. At present,...