Liver disease of different etiologies confers significant morbidity and mortality and hence it constitutes a major health concern worldwide. Stemming from a range of causes, such as viral, drug-induced, alcoholic, or autoimmune, the rate of...
Autoimmune hepatitis (AIH) is an autoimmune liver disease characterized by immune-mediated necroinflammatory liver damage associated with CD4 + T cell infiltration in liver parenchyma. Despite advances in the understanding of AIH, its etiology...
Safety in transportation systems is a global concern with millions of road accidents happening worldwide every year. Despite sophisticated advancement in automotive design and accident serverity reduction technologies, traffic fatalities continue...
Automated trust negotiation is a new approach to access control and authentication for the open systems such as the Internet, where sensitive interactions sometimes occur among entities with no prior knowledge of each other. Trust negotiation...
Traditionally, mast cells have been studied for their role as proinflammatory effector cells in allergic disorders. Recent findings however have opened up the discussion in the community of immunologists regarding MCs should be considered as...
The opportunistic pathogen Pseudomonas aeruginosa secretes a protein that triggers the accelerated degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) in airway epithelial cells. This protein, known as the CFTR inhibitory...
Earth's high latitude ionosphere, highly disturbed by particle and energy inputs and associated aurora, is the stage for plasma wave activity across a wide range of frequencies. These waves often exhibit strikingly distinct time-frequency structure...
Computer generated 3-D images are proving useful in a wide variety of applications including data visualization, computer animation, virtual reality, telepresence and terrain generation. High-end applications in these fields require images to be...
For a long-lived metastable system, the decay of the survival probability is typically exponential. However, deviations are known to exist at short times (the quantum Zeno effect) and at long times (algebraic tails in classical hydrodynamic...
The accelerated expansion of space in the Universe has been known for two decades. However, finding a plausible theory that describes this expansion is more difficult: Taking general relativity for granted requires us to stipulate the existence of...
Vibrio cholerae is the etiologic agent of cholera in humans. Intestinal colonization occurs via ingestion of contaminated food and water and results in symptoms that include the production of the characteristic rice water stool, vomiting, and...
Many environmental toxicants found in pesticides, herbicides, and industrial solvents are believed to have deleterious effects on development by disrupting hormone-sensitive processes. Xenopus embryos were exposed to commonly encountered endocrine...
'Orthogonal modular forms are algebraic modular forms arising from lattices in quadratic spaces. In this thesis, we define orthogonal modular forms, establish their basic properties, and then apply them to a case of ternary quadratic spaces to...
An organism's long-term survival is critically dependent on its ability to protect itself from pathogenic microbial infections. The first line of defense against such infections is the branch of the immune response referred to as the innate immune...
Van Allen radiation belts -- Mathematical models. Electrons -- Diffusion -- Mathematical models. Magnetohydrodynamic waves -- Mathematical models.
It is becoming increasingly important to understand the dynamics of radiation belt energetic particles given their potentially hazardous effects on satellites and our ever-increasing dependence on those satellites. There is a need to determine...
As methicillin-resistant Staphylococcus aureus (MRSA) hospitalizations keep increasing, the understanding of the characteristics that make one isolate more successful over another is paramount. Strain variations among Staphylococcus aureus observed...
This thesis contains material relating to two separate subjects. The first section determines when the C*-algebra affiliated to a directed graph has continuous trace. We use groupoid methods and the focus is on producing conditions on a graph that...
During an immune reaction to an invading pathogen, a population of lymphocytes with receptors that specifically recognize the pathogen are activated and become memory cells. Characteristically, memory lymphocytes persist for long periods of time...
American beech -- Ecology -- North America -- Mathematical models. Beech bark disease -- Mathematical models. Fungal populations -- Mathematical models. Nonindigenous pests -- Environmental aspects -- Mathematical models.
When a nonnative insect or pathogen becomes established in a forest, outcomes for host trees can range from local or minor effects to regional extirpation. Elevated host mortality is often accompanied by compensatory recruitment by co-occurring...