Among Dartmouth alumni leaders from the Greater Boston area who will serve as Vice-Chairmen during the Special Gifts phase of the College's current Capital Gifts Campaign are these five businessmen, shown at a recent meeting of campaign workers....
Indians hold pow-wow- Alumni in Hawaii of famous New Hampshire college met for luncheon get-together ast wednesday, talkded over old times and decided to hold informal gatherings once a month. In the illustration, front row left to right H. A....
Lacrosse Teams Freshman, 1954; Class of 1957; Top row; left to right: Davidoff, D. E. '56 (Manager); Michael, K. D. '29 (Coach); Konheim, B. B.; Bailey, J. P., Jr.; '55 (Manager); Middle row; left to right: Mann, R. D.; Powers, G.; Wheeler, E. H.;...
The demand for novel molecularly targeted drugs will continue to rise as we make progress toward personalizing cancer treatments to the molecular signatures of individual tumors. While the collection and analysis of genomic data has become routine,...
Casimir effect. Zero-point field. Electric conductivity. Quantum electrodynamics.
The Casimir force arises from an alteration of boundary condition in vacuum and is often regarded as a manifestation of quantum zero point energy. Considerable progress has been made in the last decade with an impressive achievement of experimental...
Although genome-wide association studies (GWAS) and other high-throughput initiatives have led to an information explosion in human genetics and genetic epidemiology, the mapping from genotype to phenotype remains challenging as most of the...
Mentally ill -- Care -- Decision making. Mental illness -- Treatment -- Decision making. Mental health services -- Decision making. Mental health -- Information services. Medical informatics. Mental Disorders -- drug therapy.
Objective. We explored preferences and perceptions about treatment decision-making roles among persons with severe mental illness and evaluated two computer-based medication values clarification tools. Methods. In this study we conducted a pilot...
Acyl-CoA:Cholesterol Acyltransferases (ACATs) are key enzymes in cellular cholesterol metabolism. ACAT converts free cholesterol to cholesterol ester, which makes it more easily storable in lipid droplets. There are two ACAT genes encoding two...
Medicine -- Study and teaching -- Audio-visual aids. ; Communication -- Audio-visual aids. ; Medical history taking. ; Physician and patient. ; Psychometrics.
The Patient Video Interview (PVI) is an instrument designed to assess communication skills in medical education that overcomes some of the drawbacks of other assessment methods. Three studies were conducted to: (a) determine a measurement system...
Since its discovery in the 1930's, the Cherenkov effect has been paramount in the development of high-energy physics research. It results in light emission from charged particles traveling faster than the local speed of light in a dielectric...
The ubiquitous complexity of common diseases is one of the biggest challenges facing the field of personalized treatments and precision medicine. This complexity can be attributed to various sources such as the genetic make-up of an individual,...
The discovery of the Van Allen radiation belts in the 1958 was the first major discovery of the Space Age. There are two belts of energetic particles. The inner belt is very stable, but the outer belt is extremely variable, especially during...
The advent of hypervisors revolutionized the computing industry in terms of malware prevention and detection, secure virtual machine managers, and cloud resilience. However, this has resulted in a disjointed response to handling known threats...
The identification of molecular alterations present in cancer is critical to better understand carcinogenesis as well as the clinical trajectories of patients with malignant tumors. Early detection and application of appropriate treatment...
The pain that follows nerve injury is chronic and consistently refractory to available analgesics. Neuropathic pain syndromes include deafferentation pain, diabetic, cancer and ischemic neuropathies, phantom limb pain, trigeminal neuralgia,...
Van Allen radiation belts -- Mathematical models. ; Magnetosphere -- Mathematical models. ; Magnetohydrodynamics -- Mathematical models.
The physics of geomagnetically-trapped radiation has been a topic of interest since the discovery of the Van Allen belts in 1958. As the energetic particles comprising these belts can pose a hazard to human activity in space, considerable effort...
Lowest order charged particle motion in the Earth''s magnetosphere can be explained using simple adiabatic theory. However, nonadiabatic theory is required to explain particle behavior in cases such as when the particle's gyroradius is large...
Autoimmune hepatitis (AIH) is an autoimmune liver disease characterized by immune-mediated necroinflammatory liver damage associated with CD4 + T cell infiltration in liver parenchyma. Despite advances in the understanding of AIH, its etiology...
Relativity (Physics). ; Anisotropy -- Mathematical models. ; Einstein field equations. ; Newtonian fluids. ; Astrophysics.
We study the effects of anisotropic pressure on the properties of spherically symmetric, gravitationally bound spheres. We consider the full general-relativistic and Newtonian treatment of this problem and obtain exact solutions for various forms...
Measurement of the ionospheric thermal particle population bridges the two different communities of ground-based radar and space-based rocket studies, which have the common goal of characterizing heavy ion transport in the cusp/cleft region. We...
Soils -- Lead content -- New Hampshire. ; Soils -- Lead content -- Vermont. ; Lead -- Environmental aspects -- New Hampshire. ; Lead -- Environmental aspects -- Vermont. ; Atmospheric deposition -- Environmental aspects -- New Hampshire. ; ...
A basic understanding of how atmospherically-derived elements behave in soils is of concern in contaminant transport, nutrient cycling, and carbon sequestration studies. Here, I use stable and radioactive tracers to evaluate the fate of...
Identifying and understanding sources of individual variation in fecundity is of central importance to life history theory and population ecology. In this study, I first examined how factors on the breeding grounds in eastern Maryland affected the...
Understanding trace element homeostasis in plants has a direct impact on global health. Much of the developing world suffers from nutrient deficiencies, and subsists on a plant based diet often lacking bioavailable nutrients like iron and zinc. At...
Space plasmas. ; Magnetopause. ; Solar wind. ; Magnetic flux. ; Plasma astrophysics.
Two types of two-dimensional (2-D), coherent (time-stationary) space plasma structures, described by one-fluid, magnetostatic and isotropic plasma theory, are examined. One is the internal structure of the Earth's magnetopause and the other is...
Epistasis (Genetics) Bioinformatics -- Methodology. Genetics -- Data processing. Medical Term Computational Biology -- methods.
A goal of human genetics is the prediction of an individual's risk of common human diseases from their genome sequence. Currently genome-wide methods to measure genetic variation across individuals exist, but methods to effectively analyze these...
Retinal degeneration -- Genetic aspects. Photoreceptors -- Molecular aspects. Cell death.
Endocytosis.
Rhodopsin.
NF-kappa B (DNA-binding protein)
Cellular signal transduction.
In humans, progressive loss of vision accompanies many inherited retinal degenerative disorders. In many cases, the affected genes are known. However the molecular pathway of photoreceptor cell death is still elusive. In this thesis, I describe the...
Voltage-dependent sodium channels (Na v ) are critical determinants of the ability of a neuron to generate and propagate action potentials. While a large family of Na v isoforms has been identified, the impact of specific isoforms on the electrical...
The completion of the Human Genome Project in 2003 and the HapMap Project in 2005 has broadened the spectrum of genetic research tools that allow researchers to conduct genome-wide association studies (GWAS) for detecting genetic variants that...