Vaccines are one the greatest advances in public health. Vaccines work by priming cells of the adaptive immune system in such a way that they remember that they have encountered a specific antigen before. This then allows those cells to respond...
Patients with cystic fibrosis (CF) are susceptible to respiratory tract infections at an early age; with the most frequent initial isolate being the Gram-positive pathogen Staphylococcus aureus. Subsequently, these patients become chronically...
While anthropogenic emissions of the toxic element mercury (Hg) to the atmosphere are currently rising, major uncertainties remain in determining the relative impacts of anthropogenic activity and natural processes on the global Hg cycle. In this...
Studies presented in this dissertation focus on the transcriptional targets and cellular functions of [Delta]Np63[alpha], the predominant TP63 isoform expressed in epithelial stem cell compartments. TP63, a member of the p53 family of...
Gene regulation is a principle tool that all organisms utilize to control development, growth, and responses to environmental conditions. Understanding how organisms orchestrate the spatiotemporal regulation of gene expression remains a fundamental...
Medicine -- Religious aspects. Health -- Religious aspects. Spirituality -- Health aspects. Spirituality -- Testing. Primary care (Medicine). Patients -- Religious life.
Background . Although the epidemiology of spirituality/religion is still an emerging field, initial research suggests spirituality may promote better health. Additionally, physician-inquiry about spirituality may enhance the quality and possibly...
Epithelium -- Tumors -- Genetic aspects.
p53 antioncogene -- Regulation.
Stem cells.
Breast -- Cancer -- Genetic aspects.
Breast -- Cancer -- Etiology.
Medical Terms: TP63 protein, human; Tumor Suppressor Proteins -- genetics; Breast Neoplasms --...
Efforts to elucidate the events that account for breast cancer initiation have focused sharply on a small subset of mammary epithelial cells, referred to in this document at mammary stem cells, whose features may enable them to accumulate and...
Studies have implicated the essential role of Vitamin A (VA) and its active metobolite, retinoic acid (RA) in both host defense and tolerance through manipulation of various immune cells, including T cells, B cells, macrophages and others. CD8⁺ T...
Dartmouth Sports Office of Sports Information Dartmouth College Atheltic Council Hanover NH 03755 Jack DeGange, Director Telephone: (603) 646-2468 1970 Varsity and Freshman Wrestling Front Row: (ltor) Henry Zanetti, Paul Douglas, Bob Elliott, Paul...