We pose several adversarial variants of the multi-armed bandit scenario and propose new approaches for their play and analysis. Our casino patron seeks to discover information about an unknown system as a means to long-term payoff -- exploration...
Webster Daniel Paintings, Engravings, etc. (Includes Cartoons) 1
Webster Daniel Paintings, Engravings, etc. (Includes Cartoons) 1; "This sir, is my case! It is the case not merely of that humble institution, it is the case of every College in our land!...It is, sir, as I have said, a small College. And yet ...";...
Thermodynamics, and the classic balance between entropy and enthalpy, provides a proverbial zoo of exotic phase behaviour that chemists can harness to create new materials out of simple liquids and polymers. The diversity of self-assembling...
The Greenland Ice Sheet (GrIS) is responding sensitively to climate change and its meltwater has the potential to influence global sea level. Recently, large changes in the GrIS have occurred including increased velocities of outlet glaciers and...
Proteins are ubiquitous in cells and are essential to a wide range of biological processes. Since existing proteins occupy only a small portion of the space of possible amino acid composition, understanding their sequence-structure-function...
Vibrio cholerae is the etiologic agent of the severe diarrheal disease cholera. Colonization of the host environment by V. cholerae requires the type IV toxin co-regulated pilus (TCP). Adequate colonization by V. cholerae is essential for cholera...
Despite all the efforts and progress in cancer research, cancer remains a devastating disease. After more than 120 years of research, immunotherapy provides a realistic hope to cure cancer. Several formats of immunotherapy, such as...
Spatial heterogeneity inherent in ecological systems impacts both diversity and community structure. However, little is known about the influence of habitat heterogeneity on temporal variability in communities. I performed several studies to...
Two alloys, Fe 55 Mn 19 Al 26 and Fe 30 Ni 20 Mn 35 Al 15 , were studied in this research project. The yield stress anomaly (YSA) of Fe 55 Mn 19 Al 26 single crystal was observed with a yield stress peak at 700 K. In situ TEM straining revealed...
The Hedgehog (Hh) and Wnt pathways are key biological signaling pathways responsible for embryonic development, cellular proliferation, stem cell maintenance and self-renewal, and adult somatic tissue homeostasis. Because these pathways serve as...
Even though 25 years have passed since the discovery of MYC, a complete understanding of the mechanism(s) of transcriptional control by this oncogenic transcription factor has not been achieved. Mcy is one of the most frequently deregulated...