Dartmouth Digital Library Program

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The sturucture and function of brain networks underlying self-evaluation / by Robert S. Chavez
Humans have a seemingly unique capacity to reflect upon information about the self to form evaluative attitudes that influence their quality of life and predict mental health outcomes. While psychologists have devoted decades of research to the...
Dartmouth Dissertations

Student Groups 3
Student Groups 3
Geographical distribution (Student Groups) Ten of Seattle's Sixteen representatives at Dartmouth gather on the steps of Dartmouth Hall. Sitting from left to right are: Bob DeBruyn, Bob Poyneer, John Milligan, Jim Silen, Dave Maryatt (wearing...
Dartmouth College Photographic Files

Student Groups 3
Student Groups 3
Geographical distribution (student groups) Received in Mar. 1956; These Dartmouth students shown standing in front of the main entrance to Baker Memorial Library in Hanover, N.H. are all from the Seattle area. They are, from left to right, front...
Dartmouth College Photographic Files

Cognitive and neural mechanisms of social motivation / by Katherine E. Powers.
The need for social connection is a pervasive and powerful human drive. When this fundamental need is not fulfilled, people place greater emphasis on forming social bonds and are motivated to behave in ways consistent with accomplishing these...
Dartmouth Dissertations

Affective decision-making in rhesus monkeys : reward order risk and the roles of the anterior insula and premotor cortex / by Eric R. Xu.
From deciding what to eat first or what stock to invest in, the order in which we prefer to experience events and the amount of risk we are willing to undertake are factors that influence our choices. However, the mechanisms underlying order and...
Dartmouth Dissertations

Interleukin-2 analogs with enhanced biological response: a novel ligand based mechanism.
Interleukin-2 -- Derivatives. ; Interleukin-2 -- Receptors. ; Ligand binding (Biochemistry).
Interleukin-2 (IL-2) is an immunoregulatory cytokine whose biological effects are mediated through interaction with specific receptors (IL-2R) on the surface of target cells. Due to its presumed role in generating a normal immune response, IL-2 is...
Dartmouth Dissertations

Endogenous antitumor immunity elicited by adoptively transferred lymphocytes through CCL5 and CD40L signaling, and dendritic cell depletion.
Ovaries -- Cancer -- Immunotherapy. T cells -- Therapeutic use. CD4 antigen -- Therapeutic use. Dendritic cells -- Therapeutic use. Chemokines -- Physiological effect. Cellular signal transduction.
Adoptive cell transfer (ACT) is a promising therapy for various non-epithelial tumors but has not yet proven successful in ovarian cancer. Moreover, its effect upon endogenous antitumor immunity, and the contribution of CD4 + T cells, remain...
Dartmouth Dissertations

Physiology and kinetics of cellulose fermentation by Clostridium thermocellum / by Evert K. Holwerda
Cellulolytic microorganisms hold promise for industrially applied microbial cellulose utilization in the generation biofuels from renewable resources. Consolidated bioprocessing (CBP), a one-step process combining cellulase production, cellulose...
Dartmouth Dissertations

The cognitive dynamics underlying decision-making : interactions between attention memory and reward in action control / by Kanghoon Jung.
A fundamental question in decision neuroscience is how cognitive processes underlying decision-making give rise to efficient decisions, especially in complex situations with multiple choice options, and each option consisting of multiple attributes...
Dartmouth Dissertations

The role of mediator in white-opaque switching / by Anda Zhang.
The multisubunit eukaryotic Mediator complex integrates diverse positive and negative gene regulatory signals and transmits them to the core transcription machinery. It is also involved in chromatin structure related epigenetic silencing through...
Dartmouth Dissertations

Studies on hepatic uroporphyrinogen oxidation and its role in the uroporphyria caused by polyhalogenated aromatic hydrocarbins.
Porphyrins -- Oxidation. Aromatic compounds. Hydrocarbons.
Dartmouth Dissertations

The effects of context and familiarity on person perception: examining the neural substrates of facial attractiveness.
Face perception -- Physiological aspects. Face perception -- Social aspects. Sex differences (Psychology). Neuropsychology.
The general objective of the current thesis was to investigate the neural substrates underlying the perception of opposite-sex faces. Building on what is already known about the distributed network of brain areas supporting various dimensions of...
Dartmouth Dissertations

Synthesis of Elaeocarpus alkaloids via pyrrolinium ion trapping.
Elaeocarpaceae. ; Alkaloids -- Synthesis. ; Pyrrolizidines.
Dartmouth Dissertations

Regulation of human type I Fc[gamma] receptor by interferon-[gamma] and dexamethasone.
Fc receptors. ; Cellular control mechanisms. ; Interferon. ; Dexamethasone.
Dartmouth Dissertations

Rewards and self-regulation in the resting brain / by Jeremy Ford Huckins
The ability to resist highly tempting reward impulses is a struggle that all humans face on a daily basis, one that gives rise to many societal problems such as obesity and drug addiction. This form of self-regulation involves a critical balance...
Dartmouth Dissertations

Dispositional emotional expressivity shapes the processing of facial expression / by Annemarie C. Brown
When we want to know what others are thinking or feeling, we look to their face for clues. Affective neuroscience has usefully documented behavioral, psychophysiological and neural responses to the facial displays of others. Though this work...
Dartmouth Dissertations

Relating behavioral control and brain development : insights from adolescence / by Heidi Catherine Meyer
Across mammalian species, adolescence is characterized by a unique combination of cognitive, behavioral and neurobiological changes. Behavioral tendencies observed during this period promote a variety of flexible interactions with the surrounding...
Dartmouth Dissertations

An analysis of an ecdysterone response element from the Drosophila hsp27 gene.
Ecdysone. ; Gene expression. ; Drosophila -- Genetics. ; Heat shock proteins.
Dartmouth Dissertations

The function of perceived gaze direction in emotion and person perception.
Gaze -- Psychological aspects. ; Facial expression. ; Body language.
The primary goal of the current research was to examine the effect of perceived gaze direction on the perception and processing of facially communicated emotion. There is good reason to believe that gaze direction and facial displays of emotion...
Dartmouth Dissertations

Reward and self-regulation in online digital environments.
Reward (Psychology). ; Self-control. ; Internet addiction -- Physiological aspects. ; Behavior Addictive -- pathophysiology.
The motivational and rewarding properties of our immediate environment affect how humans interact with our world in a number of ways. One important aspect in which reward representation shapes behavior is in the development, maintenance and...
Dartmouth Dissertations

Hepatic T cells and MDSCs in TGF-ß1-deficient mice.
Chronic active hepatitis -- Pathogenesis. ; Suppressor cells. ; Transforming growth factors-beta. ; CD4-Positive T-Lymphocytes -- immunology. ; Transforming Growth Factor beta1 -- immunology.
Autoimmune hepatitis (AIH) is an autoimmune liver disease characterized by immune-mediated necroinflammatory liver damage associated with CD4 + T cell infiltration in liver parenchyma. Despite advances in the understanding of AIH, its etiology...
Dartmouth Dissertations

Use of ionomics to identify genes that play a role in Arabidopsis metal homeostasis.
Arabidopsis -- Genetics. ; Cobalt -- Metabolism -- Genetic aspects. ; Iron -- Metabolism -- Genetic aspects. ; Nickel -- Metabolism -- Genetic aspects. ; Homeostasis.
Understanding trace element homeostasis in plants has a direct impact on global health. Much of the developing world suffers from nutrient deficiencies, and subsists on a plant based diet often lacking bioavailable nutrients like iron and zinc. At...
Dartmouth Dissertations

Demography of a fragmentation-sensitive songbird: edge and ENSO effects.
Rufous-crowned sparrow -- Effect of habitat modification on. ; Rufous-crowned sparrow -- California Southern. ; Fragmented landscapes -- California.
The Rufous-crowned Sparrow (Aimophila ruficeps ; RCSP) is a non-migratory, ground-nesting songbird that resides in southern California coastal sage scrub, which has been highly fragmented by urban development. RCSP's spatial pattern of abundance...
Dartmouth Dissertations

The 4S polycyclic aromatic hydrocarbon-binding protein: isolation, characterization, and evidence for the modulation of cytochrome P-4501A1 gene expression.
Polycyclic aromatic hydrocarbons -- Genetics. ; Enzyme induction. ; Oxidation -- Genetics.
Dartmouth Dissertations

Effects of estrogens on induction of cytochrome P450 in cultured hepatocytes.
Cytochrome P-450. ; Enzyme induction. ; Estrogen.
Dartmouth Dissertations

Metabolic engineering of high yield ethanol production in Thermoanaerobacterium saccharolyticum.
Microbial metabolism. ; Microbial genetic engineering. ; Thermophilic bacteria -- Genetic engineering. ; Anaerobic bacteria -- Genetic engineering.
A sustainable energy future is critical for environmental and strategic reasons. One alternative to petroleum used for transportation is ethanol derived from cellulosic biomass. The major barrier for biomass conversion is a cost effective method...
Dartmouth Dissertations

Chimeric NKG2D receptor expressing T cells as immunotherapy for cancer.
T cells -- Receptors. Killer cells. Cell-mediated cytotoxicity. Cancer -- Immunotherapy.
Despite advances in standard treatment options such as surgery, chemotherapy, and radiation, cancer remains the second leading cause of death in the United States. Moreover, many current therapies result in adverse effects. Therefore the...
Dartmouth Dissertations

Collaborative automated trust negotiation.
Computer networks -- Security measures. Computers -- Access control.
Automated trust negotiation is a new approach to access control and authentication for the open systems such as the Internet, where sensitive interactions sometimes occur among entities with no prior knowledge of each other. Trust negotiation...
Dartmouth Dissertations

Characterization of post-surgical immunity and memory responses to the poorly-immunogenic B16 melanoma.
T cells. Melanoma -- Immunotherapy. Immunologic memory. Immune response -- Regulation. Medical Term T-Lymphocytes, Regulatory -- immunology. CD8-Positive T-Lymphocytes -- immunology. Melanoma, Experimental -- immunology.
The potential for the immune system to control growing tumors was recognized over a century ago. Studies during the past 20 years have presented undisputable evidence that host T cells have the ability to recognize, and kill tumor cells. However,...
Dartmouth Dissertations

Feasibility testing for magneto-optic ring cellular automata.
Cellular automata. Magnetooptical devices -- Testing. Thin film devices -- Testing.
The feasibility of a magnetic computation system was tested that consists of arranging thin film micromagnetic ring structures. Each ring is magnetized in a circular, vortex state in either the clockwise (CW) or counterclockwise (CCW) directions,...
Dartmouth Dissertations

Re-programming tumor-infiltrating dendritic cells in situ via RNAi elicits therapeutic immunity against ovarian cancer.
Ovaries -- Cancer -- Immunotherapy. Dendritic cells. Small interfering RNA. Nanoparticles -- Therapeutic use. Medical Term Ovarian Neoplasms -- therapy. RNA Interference.
Current therapies for ovarian carcinoma are based on surgical debulking followed by chemotherapy. After more than three decades implementing treatments that selectively target the tumor cell, the 5-year survival rate for metastatic ovarian cancer...
Dartmouth Dissertations

Unraveling mechanisms underlying myeloid-derived suppressor cell orchestration of ovarian cancer progression
Suppressor cells -- Cellular immunity. -- Interleukin-10 -- Pathophysiology -- Ovaries -- Cancer -- Immunological aspects. -- Myeloid cells -- immunology -- Ovarian Neoplasms -- immunology.
Dartmouth Dissertations

Local hyperthermia and nanoparticle targeting for cancer immunotherapy / by Seiko Toraya Brown.
Local hyperthermia treatment for cancer has been used clinically in combination with and to enhance the efficacy of traditional treatments such as chemotherapy and radiation. In association with recent understanding of the importance of stimulating...
Dartmouth Dissertations

The consequences of acute and chronic ambivalence for cognitive functioning, emotion, and attention / by Sarah E. Henderson.
Although ambivalence is not an everyday emotional state, it is quite prevelent during critical behavioral and life changes (e.g., smoking cessation). The goal of the present thesis was to understand the relationships between acute (Aim 1) and...
Dartmouth Dissertations

Functional connectivity of brain reward circuitry in patients with schizophrenia and cannabis use disorder : effects of cannabis and delta-9-tetrahydrocannabinol (THC) / by Adina Sheri Fischer.
Up to 43% of patients with schizophrenia suffer from a co-occurring cannabis use disorder (CUD), which results in symptom exacerbation, decreased response to antipsychotic medication, and an overall worsening of disease course. Available treatments...
Dartmouth Dissertations

Dartmouth magnetic evolutionary stellar tracks and relations / by Gregory Alexander Feiden.
Strong evidence exists showing that stellar evolution models are unable to accurately predict the fundamental properties of low-mass stars. Observations of low-mass stars in detached eclipsing binaries (DEBs) indicate that stellar models...
Dartmouth Dissertations

Encyclopedia Arctica Volume 14: Greenland, Svalbard, Etc. Geography and General
Introduction -- Climate of Greenland -- The Voyage of Powell Knutson -- Whaling: Greenland and Davis Strait Fishery -- Greenland During and Since the Second World War -- Greenland Ovibos in Captivity and Under Domestication -- Ovibos in Northeast...
Encyclopedia Arctica

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