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- Antibody mediated targeting of nanoparticles to tumor cells
- Tumors -- Treatment -- Methodology.;""Nanoparticles -- Therapeutic use."";""Cell receptors."";""Antigenic determinants."";""Neoplasms -- therapy."";""Nanotechnology -- methods."";""Epitopes.""
- Dartmouth Dissertations
- Imaging performance in advanced small pixel and low light image sensors / by Leo Anzagira
- The proliferation of mobile devices and other consumer products has greatly expanded the market for CMOS image sensors. This in turn has promoted a trend of continued improvement in image sensor performance, as companies seek to gain an advantage...
- Dartmouth Dissertations
- caption with picture: Matthew Schenker '09 (left) ...
- caption with picture: Matthew Schenker '09 (left) works in the Wilder physics lab with physics and astronomy graduate student Timothy Gilheart. Schenker received a Mellam Nanotechnology Research Fellowship from Dartmouth and is spending spring term...
- Vox of Dartmouth Images
- Characterization of transporters involved in uptake of choline and other trimethylamine-containing compounds in the opportunistic pathogen Pseudomonas aeruginosa / by Adel A. Malek.
- Tumors -- Treatment -- Methodology.;""Nanoparticles -- Therapeutic use."";""Cell receptors."";""Antigenic determinants."";""Neoplasms -- therapy."";""Nanotechnology -- methods."";""Epitopes.""
- Dartmouth Dissertations
- Ian Baker, AAAS (American Association for the Adva...
- Dartmouth College Photographic Records
- Ian Baker, AAAS (American Association for the Adva...
- Dartmouth College Photographic Records
- Ian Baker, AAAS (American Association for the Adva...
- Dartmouth College Photographic Records
- Ian Baker, AAAS (American Association for the Adva...
- Dartmouth College Photographic Records
- Ian Baker, AAAS (American Association for the Adva...
- Dartmouth College Photographic Records
- Damage identification in smart structures through sensitivity enhancing control.
- Structural control (Engineering). ; Smart structures -- Vibration. ; Strains and stresses -- Computer simulation. ; Automatic control -- Sensitivity. ; Feedback control systems.
- This thesis investigates vibration-based damage identification problems in smart structures. Vibration-based damage metrics suffer from small sensitivity of modal properties to damage, thus making it difficult to detect, locate, and determine the...
- Dartmouth Dissertations
- Silicon/silicon-germanium quantum dots with single-electron transistor charge sensors / by Mingyun Yuan.
- Si/SiGe quantum dots (QDs) are promising candidates for spin-based quantum bits (qubits) as a result of the reduced spin-orbit coupling as well as the Si isotopes with zero nuclear spin. Meanwhile qubit readout is a challenge related to...
- Dartmouth Dissertations
- Re-programming tumor-infiltrating dendritic cells in situ via RNAi elicits therapeutic immunity against ovarian cancer.
- Ovaries -- Cancer -- Immunotherapy. Dendritic cells. Small interfering RNA. Nanoparticles -- Therapeutic use. Medical Term Ovarian Neoplasms -- therapy. RNA Interference.
- Current therapies for ovarian carcinoma are based on surgical debulking followed by chemotherapy. After more than three decades implementing treatments that selectively target the tumor cell, the 5-year survival rate for metastatic ovarian cancer...
- Dartmouth Dissertations
- Quantum graphs and their spectra
- Quantum graphs.
- Dartmouth Dissertations
- Nonequilibrium dynamics of magnetic nanoparticles in biomedical applications / by Daniel Benjamin Reeves
- Magnetic nanoparticles are promising candidates for use in biomedical applications as remote sensors of biophysical properties, thermal therapy agents, and detectors of specific biomolecules. Many approaches have been used to model magnetic...
- Dartmouth Dissertations
- Harmonics based detection of magnetic nanoparticle dynamics for multiparameter biosensing
- Nanoparticles -- Magnetic properties.;""Harmonics (Electric waves)"";""Biosensors."";""Spectrum analysis."";""Brownian motion processes.""
- Magnetic nanoparticles have an increasing role in the clinical and pharmaceutical realms where their physical properties can be exploited for imaging, biological and functional sensing, control of cellular processes, therapeutics, and an array of...
- Dartmouth Dissertations
- Design, fabrication, control, and programming of MEMS micro-robots.
- Microelectromechanical systems. Robotics.
- This thesis presents technologies for the design, fabrication, operation, and control of electrostatic MEMS micro-robots. It describes prototype micro-robots, with dimensions of 60 μm by 250 μm by 10 μm, that are capable of controllable...
- Dartmouth Dissertations
- Developing robust fabrication of Si/SiGe quantum dots with integrated RF-SET charge detectors.
- Quantum dots. Heterostructures. Metal oxide semiconductors -- Design and construction. Silicon oxide. Electron gas. Ohmic contacts. Microelectronics -- Technological innovations.
- Solid-state approaches to quantum computing include quantum dot qubit implementations based on the Loss-DiVincenzo proposal. Prior work in GaAs two-dimensional electron gas (2DEG) materials serves as a proving ground for device designs that can be...
- Dartmouth Dissertations
- From nonmetal- and metal-chalcogen nanoclusters to chalcogenide nanotubes.
- Chalcogenides. Nanotubes. ; Nanostructured materials.
- A double-acceleration stage linear time of flight mass spectrometer (TOF MS) with Nd/YAG laser ablation cluster source was designed and constructed for cluster production, study and deposition. Cumulenic polycarbons SC n S ( n = 2-27) were...
- Dartmouth Dissertations
- Synthesis of multimetallic nanocomposite materials utilizing block copolymers.
- Block copolymers. Nanostructured materials -- Synthesis. Metallic composites -- Synthesis.
- Nanocomposite materials containing both gold and cobalt were synthesized using block copolymers as agents for controlling spatial organization of the nanoparticles. The targeted polymers are polystyrene- block -poly(alkyne-functional)styrene...
- Dartmouth Dissertations
- Chemico-physical and pharmacologic factors that influence delivery of IONPs to tumors in rodent breast cancer models / by Jennifer Tate.
- Nanoparticles have made significant advances in recent years in the realm of cancer therapy. These nanoparticles typically range in size from 10-250nm in diameter, allowing for differential systemic-based biodistribution. The enhanced permeability...
- Dartmouth Dissertations
- Quantifying optical tomography methods for biomolecular sensing / by Jennifer-Lynn H. Demers.
- Diffuse optical imaging techniques can be combined with standard imaging technologies such as computed tomography (CT) and magnetic resonance (MR) imaging to allow measurement of spectroscopic signals pertaining to the molecular components of...
- Dartmouth Dissertations
- Magnetic susceptibility imaging of magnetic nanoparticles / by Bradley W. Ficko.
- Magnetic susceptibility imaging of magnetic nanoparticles (mNPs) has many potential applications in biomedicine such as contrast enhanced imaging and image guidance for magnetic hyperthermia therapy. This thesis describes three imaging methods...
- Dartmouth Dissertations
- Local hyperthermia and nanoparticle targeting for cancer immunotherapy / by Seiko Toraya Brown.
- Local hyperthermia treatment for cancer has been used clinically in combination with and to enhance the efficacy of traditional treatments such as chemotherapy and radiation. In association with recent understanding of the importance of stimulating...
- Dartmouth Dissertations
- Experiment planning for protein structure elucidation and site-directed protein recombination.
- Proteins -- Structure -- Computer simulation -- Experiments. ; Amino acid sequence -- Data processing -- Experiments. Protein engineering -- Experiments. ; Recombinant proteins -- Mathematical models.
- In order to most effectively investigate protein structure and improve protein function, it is necessary to carefully plan appropriate experiments. The combinatorial number of possible experiment plans demands effective criteria and efficient...
- Dartmouth Dissertations
- System and methodology for receptor-level fluorescence imaging during surgery / by Kristian Sexton.
- Fluorescence molecular imaging will have an important clinical impact in the area of guided oncology surgery, where emerging technologies are poised to provide the surgeon with real-time molecular information to guide resection, using targeted...
- Dartmouth Dissertations
- Constitutively activated PI3K signaling accelerates tumor initiation and progression in breast and lung cancers / by Mee Rie Sheen.
- Phosphatidylinositol 3-kinase (PI3K) is a major positive regulator of the PI3K signaling pathway that regulates many important cellular functions including growth, proliferation, survival, metabolism, and angiogenesis. The PIK3CA gene, encoding the...
- Dartmouth Dissertations
- Towards the experimental verification of macroscopic phenomena in quantum electrodynamics.
- Casimir effect. Zero-point field. Electric conductivity. Quantum electrodynamics.
- The Casimir force arises from an alteration of boundary condition in vacuum and is often regarded as a manifestation of quantum zero point energy. Considerable progress has been made in the last decade with an impressive achievement of experimental...
- Dartmouth Dissertations
- Magnetic nanoparticle hyperthermia as an adjuvant cancer therapy with chemotherapy / by Alicia Ailie Petryk.
- Magnetic nanoparticle-based hyperthermia for cancer treatment is a promising technology, particularly when applied as part of an adjuvant strategy with established cancer therapies (chemotherapy, radiation and surgery). In Europe, early clinical...
- Dartmouth Dissertations
- Image reconstruction optimization and quantification for image-guided luminescent tomography / by Robert William Holt.
- Molecular imaging of cancer features is a critical part of advancing better tools for oncology management and drug discovery, yet it is still evolving as a useful tool. Diffuse Fluorescence Tomography (FT) is one approach to molecular imaging, used...
- Dartmouth Dissertations
- Novel approaches to targeting innate immunity for cancer immunotherapy / by Patrick H. Lizotte
- Many kinds of cancer, and almost universally metastatic cancer, are refractory to treatment by conventional methods: surgery, radiation, and non-specific cytotoxic chemotherapy. The dawn of the age of personalized medicine presaged 15 years ago...
- Dartmouth Dissertations
- Natural and engineered metabolism of Thermoanaerobacterium saccharolyticum during growth on plant derived mono- and polysaccharides / by Devin Hedley Currie.
- Many microbes thrive in conditions that would be detrimental to human life. These microorganisms have been dubbed extremophiles. Of these, members of a subcategory, termed thermophiles, grow optimally above 45°C. Thermoanaerobacterium...
- Dartmouth Dissertations
- Fabrication and characterization of thin film molecularly imprinted polymers.
- Imprinted polymers -- Synthesis. Molecular imprinting. Thin films.
- Molecularly imprinted polymers are artificial networks designed to have many selective binding sites that are suitable for various applications. In order to develop more of these systems, the fabrication and characterization of imprinted polymers...
- Dartmouth Dissertations
- Synthesis and evaluation of alkoxyamine initiators for nitroxide-mediated polymerization.
- Polymerization. Amines -- Synthesis. Nitroxides. Radicals (Chemistry)
- Since alkoxyamines, O-alkylated nitroxide derivatives, are important control agents for nitroxide-mediated polymerization, protocols for their synthesis should be straigh- forward, cost-effective, and versatile. We have utilized a facile method for...
- Dartmouth Dissertations
- Formation and interactions of infectious prions
- Prions. ; Proteins -- Conformation. ; Nanoparticles. ; Iron oxides. ; PrPSc Proteins.
- Dartmouth Dissertations
- The development of conductive elements for the selective detection of formaldehyde and cotinine / by Sadik Antwi-Boampong.
- The development of new materials and techniques presents an opportunity to revisit old problems. Innovations in materials engineering revolutionize the status quo by expanding the tool kit needed to develop robust solutions to complex problems....
- Dartmouth Dissertations
- Molecularly imprinted polymer and applications in nicotine sensing / by Yuan Liu.
- Chemical sensing and separation is a constant challenge intriguing many scientists. Through numerous efforts, revolutionary techniques and innovative materials have been successfully developed to solve this old problem. However, a practical but...
- Dartmouth Dissertations
- Preparation and characterization of aqueous nanoparticles from molecular and macromolecular amphiphiles.
- Nanoparticles -- Synthesis. Polymer colloids. Lipids -- Synthesis.
- Colloidal nanoparticles are particles with sizes ranging from one nanometer to several hundred nanometers, which disperse evenly in a dispersion medium. In aqueous solutions, amphiphilic molecules organize themselves to form such colloidal systems...
- Dartmouth Dissertations
- Density functional theory study of transition metal doped chalcogenides / by Stefano Poggio
- The main driving force behind the development of computers was the attempt to solve problems that would otherwise require a large amount of time to be solved. Despite the technological development that has made computers ubiquitous in daily lives,...
- Dartmouth Dissertations
- Superconducting single electron transistor for charge sensing in Si/SiGe-based quantum dots / by Zhen Yang
- Si-based quantum devices, including Si/SiGe quantum dots (QD), are promising candidates for spin-based quantum bits (quits), which are a potential platform for quantum information processing [1]. Meanwhile, qubit readout remains a challenging task...
- Dartmouth Dissertations

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