The use of non-selective vasodilators for the purpose of pulmonary vasodilation has, to date, given mixed results; systemic hypotension has been the limiting factor. Lipid soluble gases (e.g. volatile anesthetics) are capable of inducing smooth...
Information retrieval -- Mathematical models. ; Electronic information resource searching. ; Computer algorithms. ; Decision making -- Data processing. ; Mathematical optimization.
This thesis presents a unified method for simultaneous solution of three problems in Information Retrieval--metasearch (the fusion of ranked lists returned by retrieval systems to elicit improved performance), efficient system evaluation (the...
Magnetosphere -- Mathematical models. Magnetic reconnection -- Mathematical models.
In this thesis we present the results of two studies of magnetic reconnection at the dayside magnetopause using the Lyon-Fedder-Mobarry magnetospheric simulation code. The first study examined the global properties of reconnection as a function of...
Ovaries -- Cancer -- Immunotherapy. Dendritic cells. Small interfering RNA. Nanoparticles -- Therapeutic use. Medical Term Ovarian Neoplasms -- therapy. RNA Interference.
Current therapies for ovarian carcinoma are based on surgical debulking followed by chemotherapy. After more than three decades implementing treatments that selectively target the tumor cell, the 5-year survival rate for metastatic ovarian cancer...
This thesis focuses on the emergence of universal dynamical scaling in quantum critical spin systems driven out of equilibrium, with emphasis on quench dynamics which involves isolated standard critical points, multi-critical points, and...
The Mixed Lineage Leukemia (MLL1) gene was first cloned as a hot spot of chromosomal translocations in acute leukemia. More than 70 fusion proteins of MLL1 have been described in both lymphoid and myeloid leukemia and many are highly associated...
Polynomials. Finite fields (Algebra). Algebraic functions. Number theory.
The ring of univariate polynomials over a finite field shares many foundational arithmetic properties with the ring of rational integers. This similarity makes it possible for many problems in elementary number theory to be translated 'through the...
APETALA3 ( AP3 ) and PISTILLATA ( PI ) are floral organ identity genes that are necessary and sufficient for petal and stamen development. Surprisingly little is known about molecular mechanisms by which AP3 and PI proteins direct floral organ...
This thesis is divided into 2 parts. In the first part of the thesis, we describe a software based approach to speeding up the Magnetic Resonance Imaging modality. In the second part of the thesis, we describe Significance Tree Quantization, which...
Clinical medicine -- Decision making -- Mathematical models. ; Diagnosis Laboratory. ; Medical screening -- Mathematical models. ; Osteoporosis -- Diagnosis. ; Mycobacterial diseases -- Diagnosis.
This dissertation focuses on the use of decision analysis to study the optimal use of medical tests. The classic threshold model of clinical decision making provides methodological background and motivation for the dissertation. In this model,...
Let K be the function field over a finite field of odd order, and let H be a definite quaternion algebra over K. If Α is an order of level M in H , we define theta series for each ideal I of Α using the reduced norm on H. Using harmonic analysis...
Plant MADS proteins play critical roles in vegetative and reproductive development. DNA binding and yeast three-hybrid assays suggest that plant MADS proteins function as dimers or multimers. However, little is known about how plant MADS proteins...
Second harmonic generation. ; Second harmonic generation -- Mathematical models. ; Glass -- Effect of infrared radiation on. ; Glass -- Electric properties.
Three-dimensional imaging in medicine -- Mathematical models. Diagnostic imaging -- Digital techniques. Brain -- Magnetic resonance imaging. Inverse problems (Differential equations).
An accurate registration between the preoperative images and the current surgical scene is critical to image-guided neurosurgery. However, during a neuro-surgical intervention, brain tissues shift and degrade the accuracy of the registration....
A yearly breast contrast-MR scan is recommended to high-risk women because of MR's high sensitivity to breast tumors. However, breast contrast-MR yields a high number of false positives that lead to expensive and sometimes unnecessary biopsy...
Continual improvements to clinical breast imaging technologies have led to ever earlier detections and increasingly accurate localizations of female breast cancers. While these advancements have certainly improved the prognoses of many patients,...
Magnetic nanoparticle-based hyperthermia for cancer treatment is a promising technology, particularly when applied as part of an adjuvant strategy with established cancer therapies (chemotherapy, radiation and surgery). In Europe, early clinical...
The identification and characterization of functional genetic variation is essential for future advances in molecular diagnostics, pharmacogenomics, and personalized medicine. Recent attempts at identifying nucleotide level variation (somatic...
Gene set testing has become a critical tool for interpreting the results of high-throughput genomic experiments. Despite the development of robust statistical methods and extensive gene set collections, however, the results from gene set testing...
In the past few years there has been a tremendous growth in the usage of digital images. Users can now access millions of photos, a fact that poses the need of having methods that can efficiently and effectively search the visual information of...
Digital integrated circuits -- Testing. Digital integrated circuits -- Testing -- Mathematical models. Digital integrated circuits -- Design and construction.