Dartmouth Digital Library Program

Memory consolidation in temporal lobe epilepsy / by Ali Seçkin Titiz.
Epilepsy is associated with cognitive impairments which often manifest as a higher prevalence of memory impairments. Memory impairments in patients with epilepsy may persist even with sufficient control of seizures, suggesting other factors may...
Dartmouth Dissertations

Nerve growth factor and the septohippocampal system / by Lan Guo.
Nerve growth factor (NGF), the prototypic neurotrophin, is well characterized for its pro-survival and growth effects in sympathetic and sensory neurons. Acting as a target-derived factor, NGF regulates the maturation of innervating neurons, and...
Dartmouth Dissertations

Novel mechanisms of action of putative pro-apoptotic BH3 mimetics and their potential therapeutic use / by Ryan Scot Soderquist.
The BCL2 family of proteins control intrinsic apoptosis at the mitochondria through a delicate balance of pro and anti-apoptotic proteins. Anti-apoptotic proteins are frequently relied upon by cancer cells, making them ideal targets for...
Dartmouth Dissertations

The interplay between BCL2 family members in response to pharmacologically induced apoptosis
Apoptosis.; Cancer cells -- Growth -- Regulation. ; Cellular signal transduction. ; Apoptosis Regulatory Proteins -- pharmacology. ; Proto-Oncogene Proteins c-bcl-2 -- pharmacology. ; bcl2-Associated Death Protein -- pharmacology. ; Vinblastine --...
Dartmouth Dissertations

CD8+ T cell responses to acute and chronic viral infections governed by costimulatory signals and CD4 help.
T cells. T cells -- Receptors. CD antigens. CD4 antigen. Immunologic memory. Herpesvirus diseases -- Immunological aspects. Vaccinia. CD8-Positive T-Lymphocytes -- immunology. CD4-Positive T-Lymphocytes -- immunology. Herpesviridae Infections --...
The phenomenon of immunological memory has been known for thousands of years. This knowledge has been applied to vaccination, which has resulted in a dramatic reduction in the number of deaths due to infectious diseases. Immunological memory is...
Dartmouth Dissertations

Innate immune mechanisms contributing to LP-BM5 murine retroviral pathogenesis and immunodeficiency / by Megan Ashley O''Connor
LP-BM5 murine retroviral infection induces murine AIDS (MAIDS), and is characterized by profound and broad immunosuppression of T- and B-cell responses. Adaptive immune response to LP-BM5 infection, including the pathogenic role of CD4+ T-cells and...
Dartmouth Dissertations

Investigation of ER-Golgi membrane proteins influencing COPII tethering and fusion / by Indrani Mukherjee
Protein secretion is executed by the secretory pathway, which involves the delivery of membrane and soluble secretory proteins in vesicle intermediates that capture newly-synthesized proteins assembled in the endoplasmic reticulum (ER) and then...
Dartmouth Dissertations

Molecular mechanisms of vacuole membrane fusion.
Membrane fusion. ; Tonoplasts. ; Plant vacuoles. ; Saccharomyces cerevisiae -- Molecular aspects.
The docking and fusion of cellular membranes plays an essential role in the secretory and endocytic pathways and in organelle inheritance. The homotypic fusion of vacuoles from the yeast Saccharomyces cerevisiae has been used as a model system to...
Dartmouth Dissertations

Low-temperature electrical and thermal resistivities of potassium and copper: a study of DMR.
Low temperatures. ; Copper -- Thermal properties. ; Copper -- Electric properties. ; Potassium -- Thermal properties. ; Potassium -- Electric properties.
Dartmouth Dissertations

Chimeric NKG2D receptor expressing T cells as immunotherapy for cancer.
T cells -- Receptors. Killer cells. Cell-mediated cytotoxicity. Cancer -- Immunotherapy.
Despite advances in standard treatment options such as surgery, chemotherapy, and radiation, cancer remains the second leading cause of death in the United States. Moreover, many current therapies result in adverse effects. Therefore the...
Dartmouth Dissertations

Bridging the adaptive and innate immune system: A study on mast cells and the regulation of tumor immunity.
Mast cells -- Immunology. Tumors -- Immunological aspects. Immune response -- Regulation.
Traditionally, mast cells have been studied for their role as proinflammatory effector cells in allergic disorders. Recent findings however have opened up the discussion in the community of immunologists regarding MCs should be considered as...
Dartmouth Dissertations

Characterization of post-surgical immunity and memory responses to the poorly-immunogenic B16 melanoma.
T cells. Melanoma -- Immunotherapy. Immunologic memory. Immune response -- Regulation. Medical Term T-Lymphocytes, Regulatory -- immunology. CD8-Positive T-Lymphocytes -- immunology. Melanoma, Experimental -- immunology.
The potential for the immune system to control growing tumors was recognized over a century ago. Studies during the past 20 years have presented undisputable evidence that host T cells have the ability to recognize, and kill tumor cells. However,...
Dartmouth Dissertations

Regulation of CD8+ T cell immunity by retinoic acid / by Yanxia Guo.
Studies have implicated the essential role of Vitamin A (VA) and its active metobolite, retinoic acid (RA) in both host defense and tolerance through manipulation of various immune cells, including T cells, B cells, macrophages and others. CD8⁺ T...
Dartmouth Dissertations

Gymnastics Women's Teams
Gymnastics Women's Teams
1978-79 Dartmouth Women's Gymnastics Team-- Front row, from left: Jill Rizika, captain Holly Dustin and Suzanne Baldwin. Middle row: Kathy Shepard, Mary Eiser, Miriam Stoll and Lynn Peterson. Back row: Asst. Coach Mike Rizzuto, Suzan Chase, Kathy...
Dartmouth College Photographic Files

Gymnastics Women's Teams
Gymnastics Women's Teams
1980 Dartmouth Women's Gymnastics Team-- Fron row, standing, from left: Coach Mike Rizzuto, Debbie Himelman, Mary Eiser and Manager Jenny Merchant. Back Row seated, from left: Captain Suzan Chase, Paula Shear, Miriam Stoll, Denise Cloutier and...
Dartmouth College Photographic Files

Gymnastics Women's Teams
Gymnastics Women's Teams
1981 Dartmouth Women's Gymnastics team- Front row, from left: Coach Michael Rizzuto, Denise Cloutier, Stephanie Lifton, Captain Paula Shear, Debbie McCoy and manager Jenny Merchant. Back row, from left: Beth Cohen, Deenya Rabius, Mary Haney, Kathy...
Dartmouth College Photographic Files

Find results with:

		Thumbnail with title
		Grid with smaller thumbnails and more detail