Experimental and theoretical aspects of macroscopic and mesoscopic elastic instability are investigated in this thesis. For the theoretical investigations we utilize a Lagrangian formulation of nonlinear continuum elasticity theory, the novel...
The eukaryotic flagellum is a complex organelle that uses the force generated by dynein motors to cause beating motion of the flagellum. The central apparatus of eukaryotic flagella has been implicated in the regulation of dynein-driven motility....
PDZ protein-protein interaction domains recognize short linear motif (SLiM) sequences typically at the extreme C-terminus of a target protein. These domains often act as scaffolds, connecting target proteins to additional interaction and catalytic...
We start by introducing avoidance coupling of Markov chains, with an overview of existing results. We then introduce and motivate a new notion, uniform coupling. We show that the only Markovian avoidance coupling on a cycle is of this type, and...
Limbic system -- Psychophysiology. ; Neuropsychology. ; Cell interaction.
Previous research has identified neurons in a variety of limbic structures which discharge in relation to the animals ongoing head direction (HD) (Ranck 1984; Taube et al. 1990a) or location (O''Keefe & Dostrovsky 1971). Because these signals...
The iodothyronine deiodinases, D1, D2, and D3, play a crucial role in determining the circulating and intracellular levels of active and inactive thyroid hormone (TH), and thus have a major effect on TH action during development and adulthood. The...
In the Firefighter Problem, a fire starts at a vertex of a graph, and in discrete time units, it spreads from burned vertices to their neighbors, unless they are protected by one of the f firefighters that are deployed every turn. Once burned or...
Core binding factor (CBF) is a heterodimeric transcription factor that is essential for a number of developmental process including hemotopoiesis and bone development. CBFs contain a DNA-binding CBFα. subunit and a non-DNA binding CBFß. subunit...
The septins are a class of GTP-binding cytoskeletal proteins conserved throughout eukaryotes. They were first described as a set of cell division cycle mutants in the budding yeast Saccharomyces cerevisiae, but since their initial discovery septins...
Laser speckle monitoring is a way to measure the motion of an optically rough surface without making physical contact to that surface. Laser speckle is inherently sensitive to motion in the plane of the reflecting surface, which gives speckle...
Nanoparticles have made significant advances in recent years in the realm of cancer therapy. These nanoparticles typically range in size from 10-250nm in diameter, allowing for differential systemic-based biodistribution. The enhanced permeability...
Ultra-high molecular weight polyethylene (UHMWPE) remains the most common bearing material for total joint arthroplasty. Advances in radiation cross-linking and other post-consolidation treatments have led to a rapid differentiation of polyethylene...
Magneto-spectroscopy is used to characterize the confinement properties of strain-induced quantum wires and dots. The wires and dots are low energy regions in an ordinary GaAs/AlGaAs quantum well that are formed when microscopic...
Fir waves are spatially and temporally repeating patterns of stand development and destruction in subalpine, balsam fir-dominated forests of the northeastern United States, perpetuated by downwind migration of strips of dying trees, "dieback...
Red milkweed beetle. Insects -- Flight. Insects -- Dispersal.
Most detailed studies of insect flight and dispersal have used long flying species as subjects. Little is known of the flight ecology of comparatively short flying species. This thesis reports the findings of a 4 year study of the flight behavior...
The effects of process parameters on the microstructural and textural evolution during directional recrystallization processing were investigated. Microstructural evolution during primary directional recrystallization of 80% cold-rolled, single...
Operating systems and low-level applications are usually written in languages like C and assembly, which provide access to low-level abstractions. These languages have unsafe type systems that allow many bugs to slip by programmers. For example, in...
Prostacyclin (PGI 2 ) is a major product of COX-2 catalyzed metabolism of arachidonic acid in the endothelium and has been shown to be atheroprotective. PGI 2 signals though its G-coupled protein receptor (GPCR) the human Prostacyclin receptor...
The image of a child standing at the side of a creek and skipping stones across it exemplifies how we tend to mentally separate aquatic habitats from dry land. But there is a constant exchange of materials from land to streams, and vice-versa....