Functional magnetic resonance imaging (fMRI) is an important tool for understanding neural mechanisms underlying human brain function. Most fMRI studies use limited sets of well-controlled stimuli to understand neural systems in isolation. The...
Gustatory pheromones regulate mating behaviors in Drosophila melanogaster and represent an important model for understanding how sensory stimuli can drive behavior. However, the genes and cells involved in pheromone detection have remained poorly...
Sex determination in C. elegans leads to the development of sex-specific structures and contributes to the regulation of sexually dimorphic programmed cell death. A search for factors that regulate the sexually dimorphic cell death of the...
Protein secretion is executed by the secretory pathway, which involves the delivery of membrane and soluble secretory proteins in vesicle intermediates that capture newly-synthesized proteins assembled in the endoplasmic reticulum (ER) and then...
Mobile agents (Computer software). ; Electronic data processing -- Distributed processing. ; Sequential processing (Computer science) -- Mathematical models.
Mobile agents have received much attention recently as a way to efficiently access distributed resources in a low bandwidth network. Planning allows mobile agents to make the best use of the available resources. This thesis studies several planning...
Niemann-Pick Type C (NPC) disease is an autosomal, recessive, neurovisceral disorder associated with defects in cholesterol and glycolipid trafficking and metabolism, leading to the accumulation of cholesterol in the late endosomes and lysosomes....
Metal ions. Binding sites (Biochemistry) -- Thermodynamics. Metalloenzymes. Cellular control mechanisms. Thermometric titration. Calorimetry.
The chemistry of biology is complex and there is a great deal that is not understood. A fundamental understanding of biochemical reactions is important to aid in the identification of undiscovered reactions and is critical to fully appreciate the...
Bioinorganic chemistry is the study of metal in biological systems. While transition metals such as copper, iron and zinc are essential to all living organisms, they can also be extremely toxic. The same properties that make them necessary render...
Older people -- Medical care -- United States -- Evaluation. Chronically ill -- Medical care -- United States -- Evaluation. Ambulatory medical care -- United States -- Evaluation.
Objective . To examine how continuity is related to quality measures for chronically ill elderly patients; to the specialty and caseload of the physicians they predominantly visit; and to the regional context of where their ambulatory care is...
MicroRNAs (miRNAs) are recently discovered family of genes with short non-coding RNA transcripts of 18 to 25 nucleotides in length. lin-4 and let-7 , the founding members of the miRNA gene family, control the timing of developmental programs in the...
The goal of this thesis has been to characterize the mechanisms of anabolic androgenic steroid (AAS) modulation of γ-aminobutyric acid type A (GABA A ) receptors. I used whole cell patch clamp recording to investigate the effects of AAS on...
This thesis considers the two special sensor networks for future sensor network design: mobile sensor networks and hybrid network of sensors and robots. To investigate two types of networks, we abstract two most important aspects that are ingrained...
Epilepsy is the most common neurological disorder in children, with an incidence of 100 per 100,000 children per year. Recurrent seizures during this period in life are often distressing to the individual and the family, but arguably the most...