Casimir effect. Zero-point field. Electric conductivity. Quantum electrodynamics.
The Casimir force arises from an alteration of boundary condition in vacuum and is often regarded as a manifestation of quantum zero point energy. Considerable progress has been made in the last decade with an impressive achievement of experimental...
Partially ordered sets. ; Convex polytopes. ; Representations of groups.
This thesis deals with geometric representations of ordered sets. In a geometric representation, each element of the ordered set is assigned a geometric object, with two elements incomparable in the ordered set if and only if the corresponding...
In this thesis, we characterize and enumerate the permutations which are realized by the orbits of signed shifts, a family of discrete dynamical systems on words. The permutations, which are called patterns of the signed shifts, are given by the...
An interval order is an ordered set whose elements are in correspondence with a collection of intervals in a linearly ordered set, with disjoint intervals ordered by their relative position. The order complex of an ordered set is the simplicial...
Experimental and theoretical aspects of macroscopic and mesoscopic elastic instability are investigated in this thesis. For the theoretical investigations we utilize a Lagrangian formulation of nonlinear continuum elasticity theory, the novel...
The present thesis is focused on developing a better understanding of factors driving disease biology and overall risk using cancers of the bladder and breast as model systems. As no single approach was likely to unravel the complexities of these...
Apoptosis is important for tissue homeostasis and is the mechanism of cell death induced by many anticancer agents. The apoptotic machinery is present in all cells, such that tight regulation must exist to prevent untimely cell and tissue death. To...
In this thesis, we present different approaches to tying knots using robots by enforcing different types of constraints. We attack the problem from three different directions; mechanical design, motion planning with simple control strategies, and...
Limbic system -- Psychophysiology. ; Neuropsychology. ; Cell interaction.
Previous research has identified neurons in a variety of limbic structures which discharge in relation to the animals ongoing head direction (HD) (Ranck 1984; Taube et al. 1990a) or location (O''Keefe & Dostrovsky 1971). Because these signals...
Electronic data processing -- Distributed processing. ; Computer network architectures. ; Programming languages (Electronic computers) -- Semantics. ; Database management.
I tackle the problem of naming and sharing resources across administrative boundaries. Conventional systems manifest the hierarchy of typical administrative structure in the structure of their own mechanism. While natural for communication that...
The integration of visual and auditory events is thought to require a joint representation of visual and auditory space in a common reference frame. We investigated the coding of visual and auditory space in the lateral and medial intraparietal...
Multimedia systems -- Mathematical models. ; Information storage and retrieval systems. ; Machinery -- Alignment.
This thesis introduces multiple media correlation, a new technology for the automatic alignment of multiple media objects such as text, audio, and video. This research began with the question: what can be learned when multiple multimedia components...
In the late 1960s, Ihara began work that led to the Ihara zeta function, a zeta function which is defined on a finite graph. This function is an interesting graph invariant which gives information on expansion properties of the graph. It also...
Magnetosphere -- Mathematical models. Magnetic reconnection -- Mathematical models.
In this thesis we present the results of two studies of magnetic reconnection at the dayside magnetopause using the Lyon-Fedder-Mobarry magnetospheric simulation code. The first study examined the global properties of reconnection as a function of...
The potential of peptide mimics of V. cholerae lipopolysaccharide (LPS) to elicit cross-reactive immune responses against LPS was investigated, as an alternative approach towards the development of a cholera vaccine. Peptide mimics of two...
Magnetic nanoparticle-based hyperthermia for cancer treatment is a promising technology, particularly when applied as part of an adjuvant strategy with established cancer therapies (chemotherapy, radiation and surgery). In Europe, early clinical...
Patients with cystic fibrosis (CF) are susceptible to respiratory tract infections at an early age; with the most frequent initial isolate being the Gram-positive pathogen Staphylococcus aureus. Subsequently, these patients become chronically...
We begin with a result on the refocussing of null geodesics in space-times. We show that all oriented refocussing 2-dimensional Lorentz manifolds are also strongly refocussing. We also introduce a theory of virtual Legendrian knots. We show that...
The need for social connection is a pervasive and powerful human drive. When this fundamental need is not fulfilled, people place greater emphasis on forming social bonds and are motivated to behave in ways consistent with accomplishing these...
The overarching goal of this thesis was two-fold. First, to determine if the effects of chronic anabolic androgenic steroid (AAS) treatment on anxiety-like behaviors are sex-specific and second to determine how different environmental modulators...
Phosphatidylinositol 3-kinase (PI3K) is a major positive regulator of the PI3K signaling pathway that regulates many important cellular functions including growth, proliferation, survival, metabolism, and angiogenesis. The PIK3CA gene, encoding the...
Although genome-wide association studies (GWAS) and other high-throughput initiatives have led to an information explosion in human genetics and genetic epidemiology, the mapping from genotype to phenotype remains challenging as most of the...
The multisubunit eukaryotic Mediator complex integrates diverse positive and negative gene regulatory signals and transmits them to the core transcription machinery. It is also involved in chromatin structure related epigenetic silencing through...
The objective of this thesis was to examine the neural and physiological substrates underlying the processing of aversive information, and how individual differences in anxiety influence these responses. In a series of experiments, we utilized skin...
Liver -- Cancer -- Etiology. Hepatotoxicology. Aflatoxins -- Toxicology. Taurine. Liver -- Cancer -- Animal models.
A hypothesis that chronic aflatoxin Bi- (AFBi) induced hepatotoxicity and the resulting compensatory cell proliferation are critical for the growth of preneoplastic lesions was investigated. A commonly utilized protocol which consists of 10 doses...