In the late 1960s, Ihara began work that led to the Ihara zeta function, a zeta function which is defined on a finite graph. This function is an interesting graph invariant which gives information on expansion properties of the graph. It also...
Brain tumors account for ~2% of all cancers, with gliomas accounting for ~70% of all brain tumors. Evidence suggests that extent of resection provides both a quality of life and survival benefit to patients. Recent work has shown the utility of...
Three-dimensional imaging in medicine -- Mathematical models. Intraoperative monitoring. Cerebral cortex -- Imaging. Computer vision. Space perception.
Brain deformation models have proven to be a powerful tool in compensating for soft tissue deformation during image-guided neurosurgery. The accuracy of these models can be improved by incorporating intraoperative measurements of brain motion. We...
The opportunistic pathogen Pseudomonas aeruginosa secretes a protein that triggers the accelerated degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) in airway epithelial cells. This protein, known as the CFTR inhibitory...
Spatial heterogeneity inherent in ecological systems impacts both diversity and community structure. However, little is known about the influence of habitat heterogeneity on temporal variability in communities. I performed several studies to...
The radio-frequency single-electron transistor (RF-SET) [1-3] has attracted significant interest as one of the fastest charge detectors known today. In this thesis, we show that by designing an on-chip superconducting LC matching network for the...
Exogenous enzymes, signaling peptides, and other classes of non-human proteins represent a potentially massive but largely untapped pool of biotherapeutic agents. From a practical perspective, however, the use of foreign proteins as novel...
Order picking systems -- Automation -- Computer simulation.
This research ventures into areas beyond traditional control frameworks in its focus. It integrates holonic concepts into a hierarchical control framework of a complex automated order fulfillment technology. Simulation of an actual full-scale order...
When we want to know what others are thinking or feeling, we look to their face for clues. Affective neuroscience has usefully documented behavioral, psychophysiological and neural responses to the facial displays of others. Though this work...
Fc receptors. Dendritic cells. Immune recognition.
Three types of Fc receptors for IgG, FcyRI (CD64), FcyRII (CD32), and FcyRIII (CD 16) are expressed differentially on blood leukocytes. In particular, CD64 and CD32 are constitutively expressed on mononuclear phagocytes of the human myeloid system....
Manifolds (Mathematics) Geodesics (Mathematics) Space and time.
We investigate weak and strong refocusing of light rays in a space-time and related concepts. A strongly causal space-time ( X^ n +1 , g ) is emphstrongly refocusing at x ∈ X if there is a point y ≠ x such that all null-geodesics through y pass...
Van Allen radiation belts -- Mathematical models. Electrons -- Diffusion -- Mathematical models. Magnetohydrodynamic waves -- Mathematical models.
It is becoming increasingly important to understand the dynamics of radiation belt energetic particles given their potentially hazardous effects on satellites and our ever-increasing dependence on those satellites. There is a need to determine...
Space plasmas. ; Magnetopause. ; Solar wind. ; Magnetic flux. ; Plasma astrophysics.
Two types of two-dimensional (2-D), coherent (time-stationary) space plasma structures, described by one-fluid, magnetostatic and isotropic plasma theory, are examined. One is the internal structure of the Earth's magnetopause and the other is...
The research presented in this thesis tested the hypothesis that uterine epithelial cells (UEC) are selectively responsive to bacteria and pathogen associated molecular patterns (PAMP) and that responses are influenced by estradiol (E 2 ). We...
This thesis contains material relating to two separate subjects. The first section determines when the C*-algebra affiliated to a directed graph has continuous trace. We use groupoid methods and the focus is on producing conditions on a graph that...
Magnetoencephalography -- Technique.; Magnetic susceptibility.
The measurement of human brain function is the goal of many noninvasive medical imaging modalities. Two sources of physiological contrast are commonly targeted to achieve this goal. The most direct approach to measuring neuronal activity is with...