As humans we create goals and strive toward ideals, engaging in a constant endeavor to better ourselves or maintain our success. Whether goals are distant hopes for the future, or small steps of change, success requires some control over...
The Arabidopsis catalase gene family contains at least three genes, encoding subunits which combine in tetramers to form 7 detectable isozymes. Two of these genes are within 250 bp of each other at a single locus (CAT3/1) near the top of chromosome...
Since acyl Co-A: cholesterol acyltransferase (ACAT) is believed to be involved in important physiological functions such as lipoprotein assembly, cholesterol absorption, steroidogenesis, and pathogenesis of atherosclerosis, ACAT has been studied...
Coal combustion remains an important source of toxic metal emissions. Dilute concentrations and poor understanding of their chemistries hinders reduction of these emissions. This thesis examines the chemistry of the trace metals arsenic and mercury...
Despite the recent FDA approval of the potentiator drug Kalydeco for treatment of cystic fibrosis (CF), only a small (3-5%) portion of patients benefit from this drug. Other functional classes of drugs including correctors are under clinical...
Through a series of case studies, signal processing and statistical tools, analyses of dynamic sea ice processes of drift, deformation, and ice pack expansion and decay are investigated for the Weddell Sea region during 1992. Cavitating fluid (CAV)...
Nutrients play fundamental roles in biological systems, affecting plant growth and quality, community structure, and species interactions. Although the effects of nutrients on primary and secondary production have been well documented, their...
The proliferation of mobile devices and other consumer products has greatly expanded the market for CMOS image sensors. This in turn has promoted a trend of continued improvement in image sensor performance, as companies seek to gain an advantage...
Objectives: This dissertation comprises three essays on geographic variations in healthcare, and the association between utilization and health outcomes. I first explore associations between outpatient visits and Medicare beneficiaries'...
The overarching goal of this thesis was two-fold. First, to determine if the effects of chronic anabolic androgenic steroid (AAS) treatment on anxiety-like behaviors are sex-specific and second to determine how different environmental modulators...
Metabolic engineering of the catabolic end-product metabolism of Thermoanaerobacterium saccharolyticum was initiated. T. saccharolyticum is an anaerobic, thermophilic bacterium that utilizes xylans and xylose, the second most prominent sugar after...
PDZ domains are protein:protein interaction domains that serve as molecular scaffolds, especially in the case of specialized cellular environments like polarized airway epithelial cells of the human lung. Historically the domains have been thought...
Some biomacromolecules require a metal co-factor to stabilize their physiologically active three-dimensional structure. The fundamental thermodynamic values of the binding of metal ions, particularly Zn2+, to a set of biomacromolecules have been...