Chlorinated ethenes are ubiquitous environmental pollutants of public concern due to their potential toxicity and carcinogenicity. Under appropriate conditions anaerobic bacteria mediate the dechlorination of perchloroethylene (a common dry...
We associate, to each positive integer n , a Cayley graph to the group PSL(2.Ζ[subscript n]). We then consider the isoperimetric numbers of these graphs. In chapter three we determine upper bounds for the isoperimetric number by a detailed...
Molecular imaging of cancer features is a critical part of advancing better tools for oncology management and drug discovery, yet it is still evolving as a useful tool. Diffuse Fluorescence Tomography (FT) is one approach to molecular imaging, used...
Three-dimensional imaging in medicine -- Mathematical models. Intraoperative monitoring. Cerebral cortex -- Imaging. Computer vision. Space perception.
Brain deformation models have proven to be a powerful tool in compensating for soft tissue deformation during image-guided neurosurgery. The accuracy of these models can be improved by incorporating intraoperative measurements of brain motion. We...
Many intracellular transport events are mediated by vesicles that bud from donor membranes and then fuse with acceptor membranes. The transport of secretory proteins between the ER and Golgi compartments of the yeast Saccharomyces cerevisiae has...
ISGylation is a type 1 interferon-regulated process that involves conjugation of ISG15, an ubiquitin-like protein, to target proteins. This posttranslational modification is reversed by a deubiquitinase known as UBP43 or USP18. UBP43 is deregulated...
In this thesis we develop a theory of Fourier analysis and fast Fourier transforms (FFTs) for finite inverse semigroups. Our results generalize results in the theory of Fourier analysis for finite groups. There is a general method for generating...
Brain mapping via EEG activation is a useful tool of basic neuroscience, and has wide clinical applications as well. The mapping is achieved by means of Event Related Potentials (ERPs), task-related changes in EEG time series. The methodology of...
Today''s fastest microprocessors, logic chips, and even memory chips employ dynamic logic as the key part to achieving advanced performance. Dynamic logic only retains the correct data state briefly and is far less robust than previous technologies...
Epilepsy is the most common neurological disorder in children, with an incidence of 100 per 100,000 children per year. Recurrent seizures during this period in life are often distressing to the individual and the family, but arguably the most...
MicroRNA-10b (miR-10b) is considered a marker of disease aggressiveness in pancreatic ductal adenocarcinoma (PDAC), in view of the fact that lower levels of miR-10b are associated with better response to neoadjuvant therapy, likelihood of surgical...
Studies presented in this dissertation focus on the transcriptional targets and cellular functions of [Delta]Np63[alpha], the predominant TP63 isoform expressed in epithelial stem cell compartments. TP63, a member of the p53 family of...
Ultra-high molecular weight polyethylene (UHMWPE) remains the most common bearing material for total joint arthroplasty. Advances in radiation cross-linking and other post-consolidation treatments have led to a rapid differentiation of polyethylene...
Epilepsy is associated with cognitive impairments which often manifest as a higher prevalence of memory impairments. Memory impairments in patients with epilepsy may persist even with sufficient control of seizures, suggesting other factors may...
In the past few years there has been a tremendous growth in the usage of digital images. Users can now access millions of photos, a fact that poses the need of having methods that can efficiently and effectively search the visual information of...
In this thesis, we consider several problems relating to cyclic subgroups of the group [mathematical equation]. Each element of [mathematical equation] has a unique representative in one of the two intervals [mathematical equation] and...
ID proteins are naturally occurring dominant negative HLH-transcription factors that are highly expressed during development but generally not expressed in adult tissue except for selected cell types and some stem cells. Also, aberrant expression...
Ice mechanics. Compressibility. Fracture mechanics. Strains and stresses. Brittleness.
This work describes the effect of triaxial compressive confinement on the strength of columnar S2 ice loaded under conditions leading to brittle failure. Cubes of columnar S2 ice were tested at -10 °C under triaxial (proportional) loading where...
The Euler '-function and Carmichael -function are extremely important in modern number theory, and much work has been devoted to studying the distribution and arithmetic properties of the values of each function. One interesting unresolved question...
Infrared imaging. Image reconstruction. Optical images -- Mathematical models. Breast -- Imaging. Infrared radiation in medicine.
Finite element based reconstruction algorithms for optical property profiling in biological tissues have been developed, implemented and evaluated using simulated data and laboratory measurements obtained with near infrared continuous wave (cw) and...
The problem of moving rigid bodies efficiently is of particular interest in robotics because the simplest model of a mobile robot or of a manipulated object is often a rigid body. Path planning, controller design and robot design may all benefit...
Cytochrome P450 (CYP) 2E1 is considered the sole CYP responsible for APAP bioactivation leading to hepatotoxicity. CYP2E1 is also considered the alcohol-inducible CYP and therefore, the sole CYP responsible for alcohol-mediated increases in APAP...