Previous work in this laboratory has implicated deoxyribonuclease II (DNase II) as an endonuclease responsible for DNA digestion during apoptosis. The goal of this thesis was to isolate the cDNA encoding DNase II and study its potential role in...
Sea ice appears to form an impenetrable boundary at the ocean-atmosphere interface in polar regions, yet in fact its porous structure provides critical pathways for the exchange of heat, gases, salts, and other chemical species impacting the global...
Multisensor data fusion. Sensor networks. Plumes (Fluid dynamics). Automatic tracking. Signal processing -- Digital techniques -- Mathematics.
The work in this thesis deals with a novel approach for detecting and tracking chemical plumes in distributed sensor networks. The ultimate objective is solving the inverse location problem: given unknown sources released at unknown times, the...
This thesis constitutes the first steps in the author's program to investigate the question of when a homotopy of 2-cocycles Ï‰ = {Ï‰[subscript t]}[subscript tâˆŠ[0,1]] on a locally compact Hausdorff groupoid Æ“ induces an isomorphism of the...
This thesis centers around a generalization of the classical discrete Fourier transform. We first present a general diagrammatic approach to the construction of efficient algorithms for computing the Fourier transform of a function on a finite...
This thesis reports work on a new device to detect changes in spatially nonuniform intensity distributions, and shows how this device can be applied to the particular problem of optical vibration detection. The phase of optical radiation is very...
Developmental prosopagnosia (DP) is a neurodevelopmental disorder defined by impaired face recognition in the absence of brain damage, low-level visual deficits, or broad cognitive problems. Behavioral and neural findings suggest different types of...
Thermodynamics, and the classic balance between entropy and enthalpy, provides a proverbial zoo of exotic phase behaviour that chemists can harness to create new materials out of simple liquids and polymers. The diversity of self-assembling...
Ultra-high molecular weight polyethylene (UHMWPE) remains the most common bearing material for total joint arthroplasty. Advances in radiation cross-linking and other post-consolidation treatments have led to a rapid differentiation of polyethylene...
'Orthogonal modular forms are algebraic modular forms arising from lattices in quadratic spaces. In this thesis, we define orthogonal modular forms, establish their basic properties, and then apply them to a case of ternary quadratic spaces to...
Shape modeling is an important area in computer vision and medical imaging. Shape models have proved valuable in the tasks of object representation, recognition, and classification. This thesis focuses on shape models of 3D surfaces extracted from...
Two localized spectroscopic imaging methods were investigated to detect and discriminate microscopic pathologies at the surface of excised breast tissues in order to improve resection completeness during breast conserving surgery. A scanning in...
Magnetoencephalography -- Technique.; Magnetic susceptibility.
The measurement of human brain function is the goal of many noninvasive medical imaging modalities. Two sources of physiological contrast are commonly targeted to achieve this goal. The most direct approach to measuring neuronal activity is with...
Two auroral sounding rocket case studies, one in the dayside and one in the nightside, explore aspects of poleward boundary aurora. The nightside sounding rocket, Cascades-2 was launched on 20 March 2009 at 11:04:00 UT from the Poker Flat Research...
Electric generators -- Windings. Electric inductors -- Design and construction -- Mathematical models. Electric current converters -- Design and construction -- Mathematical models. Energy dissipation -- Mathematical models.
Magnetic components for high-frequency power conversion applications can have significant losses that compromise the performance of the converter. In particular, winding losses can be large due to high-frequency effects that are difficult to model...
PDZ domains are protein:protein interaction domains that serve as molecular scaffolds, especially in the case of specialized cellular environments like polarized airway epithelial cells of the human lung. Historically the domains have been thought...
Does early and sustained experience with two languages in childhood modify how language is processed in the adult bilingual brain? Does extensive exposure to two languages influence language processing in the bilingual brain as compared to...
In this thesis we look at several problems that lie in the intersection between combinatorial and multiplicative number theory. A common theme of many of these problems are estimates for and properties of the smooth numbers, those integers not...
'The control of waves using periodic structures is crucial for modern optical, electromagnetic and acoustic devices such as diffraction gratings, filters, photonic crystals, solar cells, sensors, and absorbers. We present a high-order accurate...
Modern distributed systems scatter sensors, storage, and computation throughout the environment. Ideally these devices communicate and share resources, but there is seldom motivation for a device''s owner to yield control to another user. We...
Phospholipase C -- Mechanism of action. Retinal degeneration -- Pathophysiology. Retinal degeneration -- Genetic aspects. Endocytosis. Rhodopsin. Cellular signal transduction. Light -- Physiological effect. Arrestin. Clathrin. Adaptor Proteins
Mutations in the Drosophila retinal-specific Phospholipase C (NORPA) cause massive retinal degeneration within five days of constant light exposure. We have previously shown that in norpA mutants persistent complexes between the light receptor...
Siegel domains. Modular groups. Hecke algebras. Forms
In the 1960s Satake proved the existence of an isomorphism between the local Hecke algebra and the ring of polynomials invariant under the action of the signed permutation group W n (the Weyl group associated to Sp n over a local field)....
The Maine Coastal Current (MCC) flows south-westward along the New England coast in the Gulf of Maine. Red tides, river-borne pollutants, and biological species are hypothesized to be transported by the MCC. The transport pathways, and their...
In large and complex networks such as the Internet and road networks, traffic routing is typically decentralized. Users in the network choose their routes independently to minimize their own delay, leading to complicated and nonintuitive outcomes...