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TARGETED MANIPULATION OF p-GLOBIN PROMOTER
CHROMATIN STRUCTURE: IMPLICATIONS FOR GENE
THERAPY OF p- HEMOGLOBINOPATHIES
A Thesis
Submitted to the Faculty
in partial fulfillment of the requirements for the
degree of
Doctor of Philosophy
in
Pharmacology & Toxicology
by
Michael J. Nemeth
DARTMOUTH COLLEGE
Hanover, New Hampshire
July 9th, 2001
Reproduced with permission of the copyright owner. Further reproduction prohibited without permission.
| Call No. | QH599 .N46 2001 |
| Author | Nemeth, Michael J. |
| Title | Targeted manipulation of ß-globin promoter chromatin structure: implications for gene therapy of ß-hemoglobinopathies. |
| Date | 2001 |
| Description | 1 online resource (x, 197 leaves) : illustrations |
| Format | application/pdf |
| Subject | Chromatin. ; Promoters (Genetics). ; Gene targeting. ; Globin genes -- Expression. ; Genetic vectors -- Therapeutic use. ; Hemoglobinopathy -- Treatment. ; Hemoglobinopathy -- Genetic aspects. |
| College | Dartmouth Medical School -- Department of Pharmacology and Toxicology. |
| Issuing Body | Dartmouth Dissertations are made available through the Dartmouth Digital Library. |
| Degree | Thesis (Ph.D)--Dartmouth College. |
| Copyright | In Copyright. This material is protected by copyright and/or related rights. You are free to use this material in any way that is permitted by copyright law that applies to your use. For other uses, you need to obtain permission from the rights-holder(s). http://rightsstatements.org/page/InC/1.0/ |
| DOI | https://doi.org/10.1349/ddlp.3294 |
| Title | nemeth2001 1 |
| Full Text | TARGETED MANIPULATION OF p-GLOBIN PROMOTER CHROMATIN STRUCTURE: IMPLICATIONS FOR GENE THERAPY OF p- HEMOGLOBINOPATHIES A Thesis Submitted to the Faculty in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Pharmacology & Toxicology by Michael J. Nemeth DARTMOUTH COLLEGE Hanover, New Hampshire July 9th, 2001 Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. |
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