In this thesis I present analyses of optical and X-ray data of early-type galaxies in nearby rich clusters as part of the NOAO Fundamental Plane Survey. Spectroscopic parameters, including linestrengths and velocity dispersions are measured for...
At the heart of computer games and computer generated films lies 3D content creation. A student wanting to learn how to create and edit 3D meshes can quickly find thousands of videos explaining the workflow process. These videos are a popular...
T cells. T cells -- Receptors. CD antigens. CD4 antigen. Immunologic memory. Herpesvirus diseases -- Immunological aspects. Vaccinia. CD8-Positive T-Lymphocytes -- immunology. CD4-Positive T-Lymphocytes -- immunology. Herpesviridae Infections --...
The phenomenon of immunological memory has been known for thousands of years. This knowledge has been applied to vaccination, which has resulted in a dramatic reduction in the number of deaths due to infectious diseases. Immunological memory is...
CYP3A has the highest affinity for oxidation of Acetaminophen (APAP) with a Km close to the concentration observed in human serum after administration of therapeutic doses of APAP. CYP3A may be induced by numerous drugs as well as alcohols. We...
A new synthetic approach to both pyrrolo[2,3- b]indoles and pyrrolo[3,4- b]indoles by the reaction of 3-nitro-1-(substituted)indoles with functionalized isocyanides is presented. The reaction between 3-nitro-1-(phenylsulfonyl)indole (185) and ethyl...
Upon activation by binding of insulin, the insulin receptor tyrosine kinase phosphorylates a group of proteins known as the insulin receptor substrates (IRS's). The tyrosine phosphorylated IRS's then act as docking/effector molecules for SH2...
B cells -- Tumors. ; Cancer -- Immunotherapy. ; T cells. ; CD antigens.
The indolent B-cell malignancies of lymphoma and myeloma account for a great number of adult cancers in the United States annually. Hi-dose combination chemotherapy, bone marrow transplants and monoclonal antibody therapeutics have improved the...
Chapter One. Synthesis and Structure of Chiral Pt(Duphos) Terminal Phosphido Complexes. Treatment of Pt halide precursors with a secondary phosphine in the presence of the base NaOSiMe 3 gave the terminal phosphido complexes Pt(Duphos)(Ph)(PMeIs)....
A novel synthetic route to the synthesis of 9-propyl-10-azacyclododecan-12-olide (1), a natural allomone isolated from the Mexican bean beetle pupa, is presented. The salient features of this synthetic route are a regioselective Beckmann...
The main theme of this thesis is to investigate the origins of photosensitizer pharmacokinetic variability, how this pharmacokinetic variation affects photodynamic therapy (PDT), and to search for innovative strategies to reduce the...
Fluorine forms the strongest single bond to carbon, however, it is well established that transition metals can lengthen and weaken C-F bonds in fluorinated ligands. Described here are studies on the activation of C-F bonds in iridium compounds...
I. Intermolecular C-S Bond Forming Reactions
The relatively small number of efficient C-S bond forming reactions in the literature prompted an investigation into the synthesis of allylic thioethers. The technology that we developed allowed us, in...
Microwave imaging (MI) is based on recovering dielectric properties (permittivity and conductivity) of materials. Over the last two decades, MI has attracted increasing interests in biomedical applications, in particular, for breast cancer...
Eider duck on nest (439) (in emulsion: 439 Eider duck on nest.) 51286 [439 July 15, 1916 Eider ducks sitting on nest.] Bird, Duck, Eider; Wilkins No.439; Original Catalog No.51286