Proteins are ubiquitous in cells and are essential to a wide range of biological processes. Since existing proteins occupy only a small portion of the space of possible amino acid composition, understanding their sequence-structure-function...
Vaccines are one the greatest advances in public health. Vaccines work by priming cells of the adaptive immune system in such a way that they remember that they have encountered a specific antigen before. This then allows those cells to respond...
Antioncogenes. ; Breast -- Cancer -- Genetic aspects.
BRCA1 has been identified as a tumor suppressor gene that is mutated in many cases of inherited breast and ovarian cancer. Recent data suggest that multiple splice forms of BRCA1 exist, but the structure and function of these alternative...
Multimedia systems -- Mathematical models. ; Information storage and retrieval systems. ; Machinery -- Alignment.
This thesis introduces multiple media correlation, a new technology for the automatic alignment of multiple media objects such as text, audio, and video. This research began with the question: what can be learned when multiple multimedia components...
Free radicals (Chemistry). ; Electron donor-acceptor complexes. ; Ions.
In this study, the initial charge separation distance and its impact on free radical ion (FRI) formation are investigated in detail. Transient photocurrent techniques together with other spectroscopic methods were used with a series of donors and...
Genetic polymorphisms. Metalloproteinases -- Genetic aspects. Metalloproteinases -- Pathophysiology. Breast -- Cancer -- Genetic aspects. Carcinogenesis.
Extra cellular matrix (ECM) provides structural support for the body and also contributes to cell proliferation and migration. Modification ECM is an important part of normal physiology, and integral to a variety of pathologies including tumor...
Naturally occurring macrocyclic tetrapyrroles of the chlorin and bacteriochlorin classes play important roles in essential biological processes, including photosynthesis and nitrogen cycling. The chromophores also show promise in various...
Village scene - Baillie Island Drying Walrus skins [in emulsion: 462] 462 51323 [462 July 26, 1916 Scenes about the village at Baillie Islands.] Ship, in water; Skins; Wilkins No.462; Original Catalog No.51323
480 (480 51360 G.H.W. The north East Cape of Herschel Island seen from Police Barracks, showing whale boats and driftwood on beach The Naval Service, Ottawa) 51360 [480 Aug 4, 1916 Herschel Island] Boat: Dwelling, wood frame; Wilkins No.480;...