Dartmouth Digital Library Program

Thumbnail

Title

Subject

Description

Collection

Examining relationships between health beliefs and medical decisions in the context of medical uncertainty.
Medical care -- Decision making. Health attitudes. Prostate -- Cancer -- Treatment -- Decision making. Prostate -- Cancer -- Patients -- Attitudes. Uncertainty. Video recording in medicine.
This dissertation used two studies to evaluate the appropriateness of a theoretical model exploring the relationships between screening/treatment beliefs and intending to be screened or treated for prostate cancer (P-CA). Study One examined...
Dartmouth Dissertations

The impact of prenatal and postnatal home visiting on utilization of care.
Home care services -- Utilization -- New Hampshire. Home care services -- New Hampshire -- Evaluation. Maternal health services -- Utilization -- New Hampshire. Infant health services -- Utilization -- New Hampshire. Prenatal care -- Utilization --...
Research objective . Research suggests that home visiting services can have a significant impact on pregnancy outcomes, child health and development, parenting and maternal life course. The effect of home visiting on utilization of health services...
Dartmouth Dissertations

Steady state NMR imaging of cerebral blood volume as an index of chronic hypoxia induced angiogenesis.
Neovascularization. Brain -- Blood-vessels -- Magnetic resonance imaging. Blood volume -- Measurement. Cerebral circulation -- Measurement. Anoxemia. Blood Volume Determination -- methods.
Angiogenesis is part of the natural defense mechanism in brain against hypoxia and ischemia. Animal models and methods for the non-invasive investigation of cerebral angiogenesis are needed. This thesis addresses the hypothesis that steady state,...
Dartmouth Dissertations

Gain experiments with a grating based free electron laser.
Free electron lasers -- Experiments. Wave guides -- Design and construction. Diffraction gratings -- Experiments. Electron beams. Infrared sources.
The far infrared region of the electromagnetic spectrum, 15-3000 Œºm in wavelength, has a paucity of narrow band laser sources. To address the issue of whether a grating based free electron laser could operate well as such a source, a grating...
Dartmouth Dissertations

Synthetic and mechanistic studies in tetrapyrrole chemistry.
Tetrapyrroles -- Synthesis. Tetrapyrroles -- Mechanism of action. Transition metal catalysts.
Previous studies have shown that the mucosal immune system is present in the female reproductive tract and under hormonal control. With the recognition that underlying stromal cells regulate epithelial cell function and hormonal responsiveness,...
Dartmouth Dissertations

Radical methodologies with indole and synthetic strategies towards the indole alkaloids, echitamine and prenostodione.
Indole alkaloids -- Synthesis. Ring formation (Chemistry). Radicals (Chemistry).
A novel radical cyclization of 2-bromoindoles was examined, generating a series of hexahydropyrrolo[3,4- b ]indoles in fair yield. This process involved the generation of a variety of indole-3-carboxamides followed by the introduction of bromine at...
Dartmouth Dissertations

New synthetic approaches to chlorins and bacteriochlorins.
Pyrroles -- Synthesis. Porphyrins -- Synthesis.
Naturally occurring macrocyclic tetrapyrroles of the chlorin and bacteriochlorin classes play important roles in essential biological processes, including photosynthesis and nitrogen cycling. The chromophores also show promise in various...
Dartmouth Dissertations

Diffuse tomography of absorbing and fluorescent optical exogenous contrast guided by simultaneously acquired magnetic resonance images.
Optical tomography. Fluorescence. Imaging systems -- Design and construction. Diagnostic imaging -- Mathematical models. Brain -- Diseases -- Diagnosis. Brain -- Magnetic resonance imaging.
Fluorescent molecules targeted to reveal information on tissue function have been used as research tools in ex vivo and subsurface characterization of diseased tissue for years. Exploiting this specificity for in vivo imaging through centimeters of...
Dartmouth Dissertations

Evaluation and engineering of Saccharomyces cerevisiae for cellulase expression and growth on insoluble cellulose.
Saccharomyces cerevisiae -- Genetics. Cellulase -- Biotechnology. Cellulose -- Biotechnology. Biomass conversion -- Technological innovations.
Dartmouth Dissertations

SGA screen identifies a cytoplasmic role for Dbp5/Rat8 and a novel player in nuclear pore complex biogenesis.
Nuclear membranes. Membrane proteins. Genetic regulation.
The coordination and coupling of the several steps in mRNA biogenesis helps to ensure proper regulation of gene expression. The DEAD-box helicase Dbp5/Rat8 is an essential mRNA export factor that has also been implicated in other steps of mRNA...
Dartmouth Dissertations

Physiological and neural mechanisms of anxiety, negativity, and threat.
Anxiety -- Physiological aspects. Threat (Psychology) -- Physiological aspects. Amygdaloid body -- Psychophysiology. Brain -- Psychophysiology.
The objective of this thesis was to examine the neural and physiological substrates underlying the processing of aversive information, and how individual differences in anxiety influence these responses. In a series of experiments, we utilized skin...
Dartmouth Dissertations

The effects of context and familiarity on person perception: examining the neural substrates of facial attractiveness.
Face perception -- Physiological aspects. Face perception -- Social aspects. Sex differences (Psychology). Neuropsychology.
The general objective of the current thesis was to investigate the neural substrates underlying the perception of opposite-sex faces. Building on what is already known about the distributed network of brain areas supporting various dimensions of...
Dartmouth Dissertations

Kinematics and space densities for the local cataclysmic variable population.
Cataclysmic variable stars. Kinematics.
I investigate the kinematics and space densities of the local cataclysmic variable (CV) population. CVs are close binary star systems composed of a white dwarf that accretes matter from a less compact companion star in Roche lobe overflow....
Dartmouth Dissertations

I. Reactivity of electron deficient indoles toward nucleophiles, Diels-Alder reactions and dipolar cycloadditions; II. Synthesis of pyrrolo[3,4-b]indoles.
Indole -- Synthesis. Indole -- Reactivity. Pyrroles. Diels-Alder reaction.
Earlier in our laboratory, a facile synthesis of the 2- and 3-nitroindoles was realized. These compounds showed promise as powerful intermediates in the synthesis of novel structures and natural products. The reactivity of 2- and 3-nitroindoles...
Dartmouth Dissertations

The importance of p53-dependent transcriptional responses in the differentiation and curability of human embryonal carcinoma.
Testis -- Cancer -- Genetic aspects. p53 antioncogene -- Regulation. Embryonal tumors -- Pathophysiology. Germ cells -- Tumors -- Pathophysiology. Cisplatin -- Mechanism of action. Tretinoin. Testicular Neoplasms -- in children. Neoplasms
Dartmouth Dissertations

Synthetic studies toward the furanosteroids.
Furans -- Synthesis. Steroid drugs. Enzyme inhibitors -- Therapeutic use. Cancer cells -- Growth -- Regulation.
The furanosteroids are an important class of natural products that have been found to effectively inhibit various biologically important enzymes. These enzymes include the phosphoinositide-3-kinase (PI3K) family and the polo-like kinase (PLK1)...
Dartmouth Dissertations

Catalytic asymmetric P-C bond formation with Pt-phosphido complexes.
Organoplatinum compounds -- Synthesis. Organoplatinum compounds -- Reactivity. Organophosphorus compounds -- Synthesis. Organophosphorus compounds -- Reactivity. Asymmetric synthesis. Phosphate carbon. Platinum catalysts.
Chapter One. Synthesis and Structure of Chiral Pt(Duphos) Terminal Phosphido Complexes. Treatment of Pt halide precursors with a secondary phosphine in the presence of the base NaOSiMe 3 gave the terminal phosphido complexes Pt(Duphos)(Ph)(PMeIs)....
Dartmouth Dissertations

The resistance to sliding along Coulombic shear faults in columnar S2 ice.
Ice mechanics. Friction. Shear (Mechanics). Strains and stresses. Ice -- Brittleness. Ice -- Ductility.
Dartmouth Dissertations

Development of a multi-high frequency electrical impedance tomography system for breast imaging.
Electrical impedance tomography. Breast -- Imaging. Imaging systems -- Design and construction.
Dartmouth Dissertations

The influence of shared mental models of nosocomial bloodstream infections on neonatal intensive care unit infection rates.
Neonatal infections -- Prevention. Nosocomial infections -- Prevention. Neonatal intensive care -- Social aspects. Neonatal intensive care -- Psychological aspects.
Statement of the problem. Nosocomial bloodstream infections (NBSIs) are a significant source of morbidity and mortality for the very low birth weight babies (VLBW) in neonatal intensive care units (NICUs). Efforts to reduce the rates of infection...
Dartmouth Dissertations

Enzymatic hydrolysis of cellulosic biomass solids prepared by leading pretreatments and identification of key features governing performance.
Cellulase -- Absorption and adsorption. Enzymes -- Biotechnology. Cellulose -- Biodegradation. Lignocellulose -- Biotechnology. Biomass conversion. Hydrolysis. Corn stover. Poplar -- Biotechnology.
Prior to biological conversion of lignocellulosic biomass, natural barriers to efficient enzymatic hydrolysis must be overcome, and a few pretreatment technologies effectively accomplish this job with chemicals. Although several factors are...
Dartmouth Dissertations

Metal-catalyzed asymmetric synthesis of P-stereogenic phosphines.
Phosphine. Phosphorus compounds -- Synthesis. Platinum catalysts. Palladium catalysts. Asymmetric synthesis. Enantiomers.
Abstract (Summary) Chapter One. Platinum-Catalyzed Asymmetric Alkylation of Bis(secondary) Phosphines. Efficient Screening and the Synthesis of an Enantiomerically Pure C 2 -Symmetric Diphosphine . Platinum-catalyzed asymmetric alkylation of...
Dartmouth Dissertations

RR Lyrae stars as tracers of stellar populations in the Galactic bulge and satellite galaxies.
RR Lyrae stars. Milky Way. Stars -- Populations.
This dissertation details the use of a new catalog of Galactic bulge field RR Lyrae variables to advance the understanding of the structure of the Milky Way Galaxy. The catalog contains 3667 RR0 Lyrae stars from the eight-year MACHO Project...
Dartmouth Dissertations

Does continuity matter?: measuring the quality of ambulatory care among chronically ill elders in the United States.
Older people -- Medical care -- United States -- Evaluation. Chronically ill -- Medical care -- United States -- Evaluation. Ambulatory medical care -- United States -- Evaluation.
Objective . To examine how continuity is related to quality measures for chronically ill elderly patients; to the specialty and caseload of the physicians they predominantly visit; and to the regional context of where their ambulatory care is...
Dartmouth Dissertations

Ground based studies of auroral medium frequency burst radio emissions.
Ionospheric radio wave propagation. Auroras -- Alaska.
Dartmouth Dissertations

Development and investigation of a decision support system to facilitate shared decision making in community mental health.
Community mental health services -- Decision making. Mentally ill -- Care -- Decision making. Psychotherapist and patient.
Background. Electronic decision support systems (EDSS) using a shared decision making framework may be a new technology to facilitate service planning in public sector mental health care. The case management context is a ripe testing ground for...
Dartmouth Dissertations

Organism interactions and forest structural change in a nonnative disease complex: Beech bark disease in North America.
American beech -- Ecology -- North America -- Mathematical models. Beech bark disease -- Mathematical models. Fungal populations -- Mathematical models. Nonindigenous pests -- Environmental aspects -- Mathematical models.
When a nonnative insect or pathogen becomes established in a forest, outcomes for host trees can range from local or minor effects to regional extirpation. Elevated host mortality is often accompanied by compensatory recruitment by co-occurring...
Dartmouth Dissertations

Synthesis and evaluation of alkoxyamine initiators for nitroxide-mediated polymerization.
Polymerization. Amines -- Synthesis. Nitroxides. Radicals (Chemistry)
Since alkoxyamines, O-alkylated nitroxide derivatives, are important control agents for nitroxide-mediated polymerization, protocols for their synthesis should be straigh- forward, cost-effective, and versatile. We have utilized a facile method for...
Dartmouth Dissertations

Novel observation of carbonyl sulfide in parahydrogen solids.
Solid hydrogen -- Thermal properties. Carbonyl compounds.
Results from a new apparatus that records high resolution FTIR spectra in parahydrogen under 3 K are reported. A modified two-stage closed cycle refrigeration system cools a novel chamber into which gaseous helium can be condensed. The sample...
Dartmouth Dissertations

Relief-based bioinformatics methods for the analysis of epistasis in genetic association studies.
Epistasis (Genetics) Bioinformatics -- Methodology. Genetics -- Data processing. Medical Term Computational Biology -- methods.
A goal of human genetics is the prediction of an individual's risk of common human diseases from their genome sequence. Currently genome-wide methods to measure genetic variation across individuals exist, but methods to effectively analyze these...
Dartmouth Dissertations

Magnet hospitals and patient outcomes.
Nursing services -- United States -- Evaluation. Nursing services -- United States -- Personnel management. Hospitals -- United States -- Administration. Outcome assessment (Medical care). Nursing Service.
Dartmouth Dissertations

Depositional environments of rifted margin sediments: insights from Neoproterozoic diamictite and cap carbonates and the Silurian Arisaig Group.
Geology, Stratigraphic -- Proterozoic. Geology Stratigraphic -- Silurian. Rocks Sedimentary -- Nova Scotia. Rocks.
Dartmouth Dissertations

Spectroscopy-based quantification of chromophores and scattering in near infrared tomography.
Near infrared reflectance spectroscopy. Breast -- Cancer -- Tomography. Breast -- Cancer -- Imaging. Breast -- Cancer -- Diagnosis. Image reconstruction. Diagnostic imaging. Image Processing
Dartmouth Dissertations

Osmium geochemistry of natural waters.
Osmium -- Isotopes. Hydrogeology. Water chemistry.
Dartmouth Dissertations

Design and end-to-end test of a cloud-based Mobile Product Authentication architecture for low resource environments
Product counterfeiting -- Prevention.;""Drugs -- Marketing -- Corrupt practices -- Nigeria -- Prevention."";""Computer architecture."";""Cloud computing -- Security measures."";""Mobile computing -- Security measures.""
Dartmouth Dissertations

Terrain classification using proprioceptive sensors
Soils -- Classification.;""Engineering geology -- Mathematical models."";""Engineering geology -- Computer simulation."";""Mobile robots."";""Autonomous robots."";""Proprioception.""
Autonomous off-road navigation in unstructured, terrain can encounter mobility difficulties even when the surface that the vehicle is driving over is level and free from obstacles. Mobility challenges result from soil characteristics that prevent...
Dartmouth Dissertations

The chemistry of arsenic and mercury under post-combustion conditions.
Arsenic wastes -- Analysis. Mercury wastes -- Analysis. Coal -- Combustion -- By-products. Fly ash. Flue gases.
Coal combustion remains an important source of toxic metal emissions. Dilute concentrations and poor understanding of their chemistries hinders reduction of these emissions. This thesis examines the chemistry of the trace metals arsenic and mercury...
Dartmouth Dissertations

New technologies for constructing C-C, C-N, and C-S bonds
I. Intermolecular C-S Bond Forming Reactions The relatively small number of efficient C-S bond forming reactions in the literature prompted an investigation into the synthesis of allylic thioethers. The technology that we developed allowed us, in...
Dartmouth Dissertations

Understanding less than nothing: investigations into the representation of negative numbers
Little behavioral research, and less neural work, has examined how we process quantities like negative numbers, which are worth less than nothing and yet have value. The goal of this dissertation was to determine whether negative number processing...
Dartmouth Dissertations

Improved synthesis and functionalization of the viridin core skeleton
The furanosteroid class of compounds issues a siren call to both chemists and biologists alike -- the intriguing pentacyclic skeleton, densely packed and highly functionalized, continues to entice synthetic minds to develop new and elegant methods...
Dartmouth Dissertations

Combinatorial optimization methods for the design of deimmunized protein therapeutics
Exogenous enzymes, signaling peptides, and other classes of non-human proteins represent a potentially massive but largely untapped pool of biotherapeutic agents. From a practical perspective, however, the use of foreign proteins as novel...
Dartmouth Dissertations

Geometrical and probabilistic methods for determining association models and structures of protein complexes / by Himanshu Chandola.
Protein complexes play vital roles in cellular processes within living organisms. They are formed by interactions between either different proteins (hetero-oligomers) or identical proteins (homo-oligomers). In order to understand the functions of...
Dartmouth Dissertations

Effects of suburbanization on plant-pollinator interactions / by Adrian L. Carper.
Urban and suburban development is a dominant factor driving ecological processes at local and regional scales and its impacts on biodiversity and ecosystem services are alarming. Pollinators, especially bees, and the ecosystem services they...
Dartmouth Dissertations

Synthesis of aryl-based cyclopentadienyl lithium compounds for self-assembly and proton relays in hydrazone-based rotary switches / by Justin T. Foy.
Chapter One: Synthesis of aryl-based cyclopentadienyl lithium compounds for self-assembly. Cyclopentadienyl (Cp) lithium derivatives are known to form [eta]⁵-coordinated, electrostatically bonded, polymeric supersandwich structures in the solid...
Dartmouth Dissertations

Role of melanin concentrating hormone (MCH) containing neurons in the lateral hypothalamus in cardiorespiratory control and energy balance / by Ningjing Li.
The lateral hypothalamus is a brain region involved in the regulation of feeding, glucose homeostasis, sleep/wake cycle, and autonomic nervous system (ANS). Melanin concentrating hormone (MCH) containing neurons, located in the lateral...
Dartmouth Dissertations

Understanding the mechanisms of transcriptional control by the oncoprotein MYC / by Mandeep Kaur.
Even though 25 years have passed since the discovery of MYC, a complete understanding of the mechanism(s) of transcriptional control by this oncogenic transcription factor has not been achieved. Mcy is one of the most frequently deregulated...
Dartmouth Dissertations

Understanding the vulnerabilities of tumors : a network-based approach to drug target discovery / by Nadia M. Penrod.
The demand for novel molecularly targeted drugs will continue to rise as we make progress toward personalizing cancer treatments to the molecular signatures of individual tumors. While the collection and analysis of genomic data has become routine,...
Dartmouth Dissertations

Estradiol regulation of innate immune protection in the human female reproductive tract / by Mickey Vinay Patel.
Estradiol is a key regulator of immune protection in the female reproductive tract (FRT). Its concentration varies during the menstrual cycle, leading to changes in innate immune protection. In this thesis, I demonstrate the multiple levels at...
Dartmouth Dissertations

Find results with:

Searching collections:

Add or remove other collections to your search:

Narrow your search by:

Title

Subject

Date

You've searched:

Thumbnail

Title

Subject

Description

Collection

QuickView

Layout options:

		Thumbnail with title
		Grid with smaller thumbnails and more detail

Find results with:

Searching collections:

Add or remove other collections to your search:

Narrow your search by:

Title

Subject

Date

You've searched:

Thumbnail Title Subject Description Collection

QuickView

Layout options:

Thumbnail

Title

Subject

Description

Collection