Van Allen radiation belts -- Mathematical models. ; Magnetosphere -- Mathematical models. ; Magnetohydrodynamics -- Mathematical models.
The physics of geomagnetically-trapped radiation has been a topic of interest since the discovery of the Van Allen belts in 1958. As the energetic particles comprising these belts can pose a hazard to human activity in space, considerable effort...
H-NS, an abundant nucleoid associated protein, has a role in silencing the expression of a variety of environmentally regulated genes during growth under nonpermissive conditions. A genetic approach was used to study H-NS regulation of genes in...
Infrared imaging. Image reconstruction. Optical images -- Mathematical models. Breast -- Imaging. Infrared radiation in medicine.
Finite element based reconstruction algorithms for optical property profiling in biological tissues have been developed, implemented and evaluated using simulated data and laboratory measurements obtained with near infrared continuous wave (cw) and...
The fluxes of radiation belt electrons are highly variable, due to a competition between various acceleration, loss, and transport processes. Studies of any of the processes are equally important. My study focuses on electron-EMIC (electromagnetic...
Limbic system -- Psychophysiology. ; Neuropsychology. ; Cell interaction.
Previous research has identified neurons in a variety of limbic structures which discharge in relation to the animals ongoing head direction (HD) (Ranck 1984; Taube et al. 1990a) or location (O''Keefe & Dostrovsky 1971). Because these signals...
The previously synthesized 3,4-dibromo-8-oxabicyclo[3.2.1]octa-3,6-dien-2-one has been shown to be a very versatile building block for the synthesis of complex natural product structures. This key building block has been made in both...
The furanosteroid class of compounds issues a siren call to both chemists and biologists alike -- the intriguing pentacyclic skeleton, densely packed and highly functionalized, continues to entice synthetic minds to develop new and elegant methods...
Optical tomography. ; Near infrared spectroscopy. ; Image analysis -- Mathematical models. ; Imaging systems -- Image quality -- Mathematical models. ; Image reconstruction -- Mathematical models. ; Least squares. Breast -- Tomography.
Diffuse optical tomography (DOT) has the potential to become a non-invasive and non-ionizing diagnostic imaging technique for breast cancer imaging. DOT uses near-infrared (NIR) light to illuminate the breast, generally through the use of fiber...
The novel heptachloro-1'-methyl-1,2'-bipyrrole (""Q1"") ( 1 ) is a natural organohalogen that has been detected in more than 100 worldwide environmental samples. In recent years mixed halogenated 1,2'-bipyrroles have also been detected in several...
Part 1 . A computational study targeting the lowest energy structure, electronic state and physical properties of small carbon clusters containing one or two heteroatoms has been done. The structural properties sought included whether the most...
This dissertation details the use of a new catalog of Galactic bulge field RR Lyrae variables to advance the understanding of the structure of the Milky Way Galaxy. The catalog contains 3667 RR0 Lyrae stars from the eight-year MACHO Project...
Mentally ill -- Care -- Decision making. Mental illness -- Treatment -- Decision making. Mental health services -- Decision making. Mental health -- Information services. Medical informatics. Mental Disorders -- drug therapy.
Objective. We explored preferences and perceptions about treatment decision-making roles among persons with severe mental illness and evaluated two computer-based medication values clarification tools. Methods. In this study we conducted a pilot...
Introduction. Nosocomial sepsis in extremely low birth weight (ELBW) infants 501-1000 grams is associated with increased mortality risk, prolonged hospitalization, and increased costs of care. Purpose. The purpose of this thesis was to evaluate the...
Breast -- Cancer -- Tomography. Near infrared spectroscopy. Breast -- Cancer -- Imaging. Breast -- Cancer -- Diagnosis.
Near-infrared (NIR) light provides potential for a new approach to non-invasive detection, diagnosis and clinical management of breast cancer. Using NIR spectroscopic imaging techniques, the physiological information about breast tissue composition...
Results from a new apparatus that records high resolution FTIR spectra in parahydrogen under 3 K are reported. A modified two-stage closed cycle refrigeration system cools a novel chamber into which gaseous helium can be condensed. The sample...
Tetrapyrroles -- Synthesis. Tetrapyrroles -- Mechanism of action. Transition metal catalysts.
Previous studies have shown that the mucosal immune system is present in the female reproductive tract and under hormonal control. With the recognition that underlying stromal cells regulate epithelial cell function and hormonal responsiveness,...
The ctx and tcp genes that encode cholera toxin and the toxin co-regulated pilus, the major virulence determinants of Vibrio cholerae, are repressed by the nucleoid-associated protein H-NS and activated by the AraC-like transcriptional regulator...
An important mode of stabilization of cations in biochemical reactions is interaction with the π systems-of aromatic residues. As part of an investigation of the interaction of carbocations with aromatic π systems, a study of various model...
Current theories of visual category learning posit a representation of category rules and visual features that critically define those categories that are encoded separately and distributed throughout the cerebral cortex. Neuroimaging and...
Violent video games are immensely popular among children and adults, making it crucial to understand how these games affect the thoughts, feelings, and behaviors of those who play them. The present research proposed an account by which video game...
Phospholipase C -- Mechanism of action. Retinal degeneration -- Pathophysiology. Retinal degeneration -- Genetic aspects. Endocytosis. Rhodopsin. Cellular signal transduction. Light -- Physiological effect. Arrestin. Clathrin. Adaptor Proteins
Mutations in the Drosophila retinal-specific Phospholipase C (NORPA) cause massive retinal degeneration within five days of constant light exposure. We have previously shown that in norpA mutants persistent complexes between the light receptor...
The furanosteroids are a special class of natural products that feature a furan ring fused to the steroid nucleus at C-4 and C-6. In 1945, viridin, the parent member of this group, was isolated by Grove and coworkers from the fungas Gliocladium...
Something must bear the load of poleward forces exerted by kinetochore-associated motors so that chromosomes move toward the poles rather than the poles towards the chromosomes. I tested this hypothesis by monitoring chromosome movement in cultured...
Voltage-dependent sodium channels (Na v ) are critical determinants of the ability of a neuron to generate and propagate action potentials. While a large family of Na v isoforms has been identified, the impact of specific isoforms on the electrical...