The goal of this work was to improve the computational tools for near-infrared light modeling for clinical applications in photodynamic therapy (PDT) analysis and eventual treatment planning. The tools to facilitate this modeling were developed in...
This thesis investigates a notion of Turing reducibility introduced by Winkler [8] that is total on all computably enumerable oracles. Groszek and Weber show in [7] that this is a new notion of reducibility and it is not transitive. They give su...
MicroRNAs (miRNAs) are recently discovered family of genes with short non-coding RNA transcripts of 18 to 25 nucleotides in length. lin-4 and let-7 , the founding members of the miRNA gene family, control the timing of developmental programs in the...
Riemannian manifolds. Singularities (Mathematics). Laplacian operator. Spectral theory (Mathematics). Riemann surfaces. Curves on surfaces. Geometry
Historically, inverse spectral theory has been concerned with the relationship between the geometry and the spectrum of compact Riemannian manifolds, where spectrum means the eigenvalue spectrum of the Laplace operator as it acts on smooth...
Goldman and Turaev constructed a Lie bialgebra structure on the free Z-module generated by free homotopy classes of loops on an oriented surface. Turaev conjectured that the cobracket of A is zero if and only if A is a power of a simple class. Chas...
We have a limited understanding of how an opinion is originated, how an opinion and information supporting and explaining it gets conveyed, and how the communicated opinion is perceived and processed by others. One direction of current research...
Fluorescence molecular imaging will have an important clinical impact in the area of guided oncology surgery, where emerging technologies are poised to provide the surgeon with real-time molecular information to guide resection, using targeted...
In utero exposure to maternal malnutrition is associated with increase offspring susceptibility to cardiometabolic and neuropsychiatric disease. Epigenetic mechanisms mediate, at least in part, fetal adaptations to adverse in utero environments...
Some biomacromolecules require a metal co-factor to stabilize their physiologically active three-dimensional structure. The fundamental thermodynamic values of the binding of metal ions, particularly Zn2+, to a set of biomacromolecules have been...
The study of twin primes gives rise to several famously difficult problems in number theory--in fact, we still cannot definitively say whether there are infinitely many twin primes. In this work, we consider a related problem, namely: What is the...
Order picking systems -- Automation -- Computer simulation.
This research ventures into areas beyond traditional control frameworks in its focus. It integrates holonic concepts into a hierarchical control framework of a complex automated order fulfillment technology. Simulation of an actual full-scale order...
The mucosal immune system of the female reproductive tract (FRT) balances the dual functions of protection against invading pathogens and adaptation of the endometrial environment for successful fertilization and implantation. Growth factors are...
Prior to biological conversion of lignocellulosic biomass, natural barriers to efficient enzymatic hydrolysis must be overcome, and a few pretreatment technologies effectively accomplish this job with chemicals. Although several factors are...
Topological graph theory. Aperiodicity. Paths and cycles (Graph theory)
The condition ""every cycle has an entry"" first appeared in the literature in Kumjian, Pask, and Raeburn's paper on Cuntz-Krieger algebras of directed graphs, where it was called Condition (L). It provides a necessary condition for simplicity of...
An organism's long-term survival is critically dependent on its ability to protect itself from pathogenic microbial infections. The first line of defense against such infections is the branch of the immune response referred to as the innate immune...
Bioinorganic chemistry, a discipline that bridges chemistry and biology, has become increasingly popular as new techniques and analytical methods have emerged to study metals in biological systems. One such technique that has become increasingly...
The inappropriate expression of Matrix Metalloproteinases (MMPs) contributes to the pathology of many cancers. Among these, melanoma is a particularly insidious disease in that it is almost completely resistant to every known the therapy, and the...
Glutamic acid -- Receptors. Ion channels -- Molecular aspects. Ligand binding (Biochemistry).
Medical Term: Glutamates.
AMPA receptors are glutamate-gated ion channels that mediate most of the excitatory synaptic signals in the central nervous system. They form tetrameric assemblies that are combinations of the subunits GluR1-4, each of which contains a...
Muscle proteins. Myosin -- Structure-activity relationships. Kinesin -- Structure-activity relationships. Mechanism of action (Biochemistry). Molecular Motor Proteins.
Protein motors, such as kinesin and myosin, use chemical energy in the form of ATP to physically move along filaments and perform complex mechanical tasks in the cell, such as intracellular transport, cell division and muscle contraction. Myosin...
A polynomial is a product of distinct cyclotomic polynomials if and only if it is a divisor over [Special characters omitted.] [x ] of xn - 1 for some positive integer n. In this thesis, we will examine two natural questions concerning the divisors...
Chronic infection of the human airway by mucoid Pseudomonas aeruginosa is cited as the leading cause of death among Cystic Fibrosis patients. The persistent nature of these infections is linked to P. aeruginosa's ability to form protective biofilm...
The potential of peptide mimics of V. cholerae lipopolysaccharide (LPS) to elicit cross-reactive immune responses against LPS was investigated, as an alternative approach towards the development of a cholera vaccine. Peptide mimics of two...
Purple sulfur bacteria (PSB) can dominate the nitrogen, carbon, and sulfur cycles in anoxic ecosystems via their anoxygenic photosynthetic metabolisms and are the only producers of the carotenoid, okenone, a biomarker targeted for photic zone...