Identifying the determinants of reproductive success in small-scale societies is critical for understanding how natural selection has shaped human evolution and behavior. The available evidence suggests that status-accruing behaviors such as...
Telecommunication -- Traffic -- Measurement -- Statistical methods. IEEE 802.11 (Standard). Universities and colleges -- Computer networks -- New Hampshire -- Hanover -- Case studies.
The edge of the Internet is increasingly wireless. Enterprises large and small, homeowners, and even whole cities have deployed Wi-Fi networks for their users, and many users never need to--or never bother to--use the wired network. With the advent...
Robots -- Control systems -- Design and construction. Mobile robots. Robots -- Dynamics.
This thesis examines the issues of vehicle and information dynamics in the control of a multi-robot system using a radial-basis potential function controller. Distributed control of multi-robot systems requires each robot to communicate state...
Hematopoietic stem cells (HSCs) balance self-renewal with the continuous production of the suitable numbers of lineage-restricted progenitor cells. In this work we demonstrate that the Mixed lineage leukemia 1 (Mll1) gene is essential for this...
Coronary artery bypass graft (CABG) surgery is a leading treatment option for extending and/or improving the quality of life for patients suffering from heart disease. While we have witnessed improvements in mortality and morbidity secondary to...
APETALA3 (AP3) is a MADS box gene required for normal development of the petals and stamens in the Arabidopsis flower. AP3 transcriptional regulation occurs in two stages; an initial establishment phase, which is mediated by LEAFY (LFY) and UNUSUAL...
Acyl coenzyme A:cholesterol acyltransferase (ACAT) is a membrane bound enzyme whose primary biochemical activity is to convert cholesterol, along with long chain fatty acyl Coenzyme A, into cholesterol esters. ACAT plays an important role in the...
Soils -- Lead content -- New Hampshire. ; Soils -- Lead content -- Vermont. ; Lead -- Environmental aspects -- New Hampshire. ; Lead -- Environmental aspects -- Vermont. ; Atmospheric deposition -- Environmental aspects -- New Hampshire. ; ...
A basic understanding of how atmospherically-derived elements behave in soils is of concern in contaminant transport, nutrient cycling, and carbon sequestration studies. Here, I use stable and radioactive tracers to evaluate the fate of...
Identifying and understanding sources of individual variation in fecundity is of central importance to life history theory and population ecology. In this study, I first examined how factors on the breeding grounds in eastern Maryland affected the...
DAM p.74 9/85; Communications Managment Associates 1724 North Wakefield St. Arlington, VA 22207; David K. Martin President; Left to right Tom Carter '63, David K. Martin '54 and Larry Harrison '53 confer about international marketing strategy for...
Magnetic nanoparticle-based hyperthermia for cancer treatment is a promising technology, particularly when applied as part of an adjuvant strategy with established cancer therapies (chemotherapy, radiation and surgery). In Europe, early clinical...
Lung cancer is the leading cause of cancer-related death in the USA and worldwide causing 160,000 and 1.5 million deaths per year, respectively. Due to the late stage of diagnosis, poor efficacy of chemotherapies (targeted and pleiotropic), and...
Thermodynamics, and the classic balance between entropy and enthalpy, provides a proverbial zoo of exotic phase behaviour that chemists can harness to create new materials out of simple liquids and polymers. The diversity of self-assembling...
We have a limited understanding of how an opinion is originated, how an opinion and information supporting and explaining it gets conveyed, and how the communicated opinion is perceived and processed by others. One direction of current research...
Objectives: This dissertation comprises three essays on geographic variations in healthcare, and the association between utilization and health outcomes. I first explore associations between outpatient visits and Medicare beneficiaries'...
Patients with cystic fibrosis (CF) are susceptible to respiratory tract infections at an early age; with the most frequent initial isolate being the Gram-positive pathogen Staphylococcus aureus. Subsequently, these patients become chronically...
The identification and characterization of functional genetic variation is essential for future advances in molecular diagnostics, pharmacogenomics, and personalized medicine. Recent attempts at identifying nucleotide level variation (somatic...
After decades of searching we have yet to find the progenitor systems for type Ia supernovae. In fact most of what we know about this homogeneous class of supernovae is from spectral features associated with the incinerated remains of the C+O white...
Access control is a core component of any information-security strategy. Researchers have spent tremendous energy over the past forty years defining abstract access-control models and proving various properties about them. However, surprisingly...
Recent years have witnessed a new class of monitoring applications that need to continuously collect information from remote data sources. Those data sources, such as web click-streams, stock quotes, and sensor data, are often characterized as...
Opinion dynamics is a complex procedure that entails a cognitive process when it deals with how a person integrates influential opinions to form revised opinion. Early research on opinion formation and social influence can be traced back to the...
Epilepsy is associated with cognitive impairments which often manifest as a higher prevalence of memory impairments. Memory impairments in patients with epilepsy may persist even with sufficient control of seizures, suggesting other factors may...
Yeast vacuole fusion involves three transmembrane SNAREs and a unique soluble SNARE, Vam7p. This SNARE cycles between vacuolar membrane-bound and cytosolic state. In its membrane-bound state, it is able to participate in vacuolar fusion by...
Phosphatidylinositol 3-kinase (PI3K) is a major positive regulator of the PI3K signaling pathway that regulates many important cellular functions including growth, proliferation, survival, metabolism, and angiogenesis. The PIK3CA gene, encoding the...
Internet -- Security measures. Public key infrastructure (Computer security). Digital signatures. Peer-to-peer architecture (Computer networks) -- Security measures.
The Internet has become a virtual place where people not only operate in isolation but also interact with other Internet users. Collaborative systems are becoming more popular. Applications now being introduced could provide better remote education...
Although genome-wide association studies (GWAS) and other high-throughput initiatives have led to an information explosion in human genetics and genetic epidemiology, the mapping from genotype to phenotype remains challenging as most of the...
Metal ions confer structural stability and reactivity to a large number of proteins that use the amino acids histidine (His) and cysteine (Cys) to form stable metal-ligand complexes. The stability of metal-His and metal-Cys interactions and their...
Despite the recent FDA approval of the potentiator drug Kalydeco for treatment of cystic fibrosis (CF), only a small (3-5%) portion of patients benefit from this drug. Other functional classes of drugs including correctors are under clinical...