The need for social connection is a pervasive and powerful human drive. When this fundamental need is not fulfilled, people place greater emphasis on forming social bonds and are motivated to behave in ways consistent with accomplishing these...
The overarching goal of this thesis was two-fold. First, to determine if the effects of chronic anabolic androgenic steroid (AAS) treatment on anxiety-like behaviors are sex-specific and second to determine how different environmental modulators...
Nutrients play fundamental roles in biological systems, affecting plant growth and quality, community structure, and species interactions. Although the effects of nutrients on primary and secondary production have been well documented, their...
Anabolic-androgenic steroids (AAS) are synthetic derivatives of the gonadal hormone, testosterone. Despite their many untoward side effects, AAS are wildly abused for their ergogenic properties. AAS have numerous effects on many organ systems,...
Dendritic cells. Biological response modifiers. Immune response -- Regulation. T cells. CD antigens. Dendritic Cells -- Immunology. Receptors
Dendritic cells (DCs) are professional antigen-presenting cells (APCs) that regulate antigen-specific T cell activation or tolerance. The maturation state of DCs is critical since immature DCs are believed to induce T cell tolerance whereas mature...
The ectomycorrhizal symbiosis between temperate forest trees and some soil fungi is an adaptation to resource limitations of both symbionts. Nitrogen enrichment of historically N-limited forest ecosystems may change this symbiosis through direct...
Gyrinophilus -- Ecology. ; Gyrinophilus -- Geographical distribution -- Northeastern States. ; Freshwater ecology -- Northeastern States. ; Amphibian populations -- Northeastern States.
I investigated controls on the distribution and abundance of the salamander Gyrinophilus porphyriticus (Plethodontidae) acting at multiple spatial scales: individual first-order streams, headwater drainages comprised of multiple streams, and the...
CD antigens. T cells -- Receptors. Receptor-ligand complexes. Transplantation immunology. Immunological tolerance -- Molecular aspects. Antigens
Voltage-dependent sodium channels (Na v ) are critical determinants of the ability of a neuron to generate and propagate action potentials. While a large family of Na v isoforms has been identified, the impact of specific isoforms on the electrical...
Climatic geomorphology -- Sierra Nevada (California and Nevada). ; Slopes (Physical geography) -- Sierra Nevada (California and Nevada). ; Weathering -- Sierra Nevada (California and Nevada). ; Chemical denudation -- Sierra Nevada (California and...
Landscapes evolve in response to external forcings such as climate and tectonics that influence the pace and patterns of erosion and weathering processes. Furthermore, internal feedbacks between erosion and weathering regulate the expression of...
CD antigens. Immune response -- Regulation. Hemoglobin.
CD163 is a monocyte- and macrophage-specific surface glycoprotein proposed to function in the maintenance of homeostasis and the resolution of inflammation. CD163 binds hemoglobin-haptoglobin complexes implicating this receptor as a hemoglobin...
An organism's long-term survival is critically dependent on its ability to protect itself from pathogenic microbial infections. The first line of defense against such infections is the branch of the immune response referred to as the innate immune...
Mast cells -- Immunology. Mast cells -- Physiology. Dendritic cells. Immunological tolerance -- Molecular aspects. Medical Term Cell Degranulation.
Mast cells (MC) have until recently been regarded as pro-inflammatory, however this view changed with the observation that the absence of MC impairs the development of transplant tolerance to allografts. However, little is known about whether MC...
Biofilm formation is a complex process culminating in a multicellular microbial structure encased in an extracellular matrix. In order for planktonic cells to initiate and proceed through biofilm formation, they must appropriately regulate a number...
Chronic infection of the human airway by mucoid Pseudomonas aeruginosa is cited as the leading cause of death among Cystic Fibrosis patients. The persistent nature of these infections is linked to P. aeruginosa's ability to form protective biofilm...
Many microbes thrive in conditions that would be detrimental to human life. These microorganisms have been dubbed extremophiles. Of these, members of a subcategory, termed thermophiles, grow optimally above 45°C. Thermoanaerobacterium...