Dartmouth Digital Library Program

Exercise and the brain : impacts on cognition neural function and mental health / by Andrea M. Robinson.
It has been well established that physical exercise has broad impacts across the lifespan, including improved cognition, brain function, and mental health. Studies investigating the mechanism underlying the cognitive enhancing effect of exercise...
Dartmouth Dissertations

Understanding inpatient nurses' engagement in worksite health promotion: a case study.
Nurses -- Health and hygiene. Employee health promotion.
Background. Worksite health promotion programs (HPP) support employees' health behaviors to prevent downstream diseases. Maximizing participation can optimize program impact. Objectives. To assess staff nurses' participation in three HPP - flu...
Dartmouth Dissertations

Novel inhibitors of MMP-1 and MMP-13 gene expression as potential therapies for arthritis.
Collagenases -- Genetic aspects. Collagenases -- Pathophysiology. Metalloproteinases -- Genetic aspects. Metalloproteinases -- Pathophysiology. Transcription factors. Extracellular matrix proteins. Cartilage -- Diseases. Arthritis -- Genetic...
Matrix metalloproteinases (MMPs) are a family of endopeptidases that collectively degrade all components of the extracellular matrix (ECM) at neutral pH. During the progression of arthritis, MMPs mediate the degradation of cartilage, which consists...
Dartmouth Dissertations

Ethical problems in predictive DNA based genetic testing created by the artifact of health insurance.
Human chromosome abnormalities -- Diagnosis -- Moral and ethical aspects. ; Health insurance -- United States. ; Discrimination in insurance -- United States.
Dartmouth Dissertations

Characterization of post-surgical immunity and memory responses to the poorly-immunogenic B16 melanoma.
T cells. Melanoma -- Immunotherapy. Immunologic memory. Immune response -- Regulation. Medical Term T-Lymphocytes, Regulatory -- immunology. CD8-Positive T-Lymphocytes -- immunology. Melanoma, Experimental -- immunology.
The potential for the immune system to control growing tumors was recognized over a century ago. Studies during the past 20 years have presented undisputable evidence that host T cells have the ability to recognize, and kill tumor cells. However,...
Dartmouth Dissertations

Modulating innate and adaptive immunity in the Toxoplasma gondii-induced model of inflammatory bowel disease.
Toxoplasma gondii -- Immunology. Inflammatory bowel diseases -- Immunological aspects. C-reactive protein. T cells. Immune response -- Regulation. Protein precursors -- Immunology.
Inbred C57BL/6 mice develop an acute necrotizing ileitis following oral infection with Toxoplasma gondii that is associated with massive inflammatory infiltrates and morphologic tissue changes consistent with human Crohn's disease. In the course of...
Dartmouth Dissertations

Structural characterization of the LysR-type virulence factor, AphB, and insight into its mehcanism of transcriptional activation at the tcpPH promoter in Vibrio cholerae
The LysR-type virulence regulator, AphB, initiates the Vibrio cholerae virulence cascade resulting in expression of the two critical virulence factors, toxin-coregulated pilus and cholera toxin, by activating transcription at the tcpPH promoter....
Dartmouth Dissertations

Role of proteolytic processing of tumor necrosis factor-[alpha] in immunopathology during influenza infection / by Matthew Peter DeBerge.
Influenza virus is a respiratory pathogen that is capable of causing considerable pulmonary pathology and respiratory dysfunction in humans. Seasonal influenza epidemics and the occasional influenza pandemic are responsible for significant...
Dartmouth Dissertations

Eleazar Wheelock, letter, to Samson Occom, 9 April 1766
1766-04-09. Breed, Gershon; Fowler, David; Fowler, James; Mason Controversy; Mason, Samuel; Occom, Aaron; Occom, Mary; Occom, Samson; Rogers, Sarah; Shaw, Nathaniel; Society in Scotland for Propagating Christian Knowledge. Board of Correspondents,...
a.l.s. photostat copy of original. Also writer's copy.
Manuscripts Related to Samson Occom and Eleazar Wheelock's Early Indian Students

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