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- Novel synthetic approaches to polycyclic aromatic hydrocarbons.
- Polycyclic aromatic hydrocarbons -- Synthesis.
- This research attempts to combine known methodology with new chemistry towards the preparation of extended polycyclic aromatic hydrocarbons (PAH). The generation and Diels-Alder trapping of 1,7- and 2,6-naphthalene bisarynes was attempted for the...
- Dartmouth Dissertations
- Estradiol regulation of innate immune protection in the human female reproductive tract / by Mickey Vinay Patel.
- Estradiol is a key regulator of immune protection in the female reproductive tract (FRT). Its concentration varies during the menstrual cycle, leading to changes in innate immune protection. In this thesis, I demonstrate the multiple levels at...
- Dartmouth Dissertations
- Development and quantification of a 3D brain deformation model for model-updated image-guided stereotactic neurosurgery.
- Three-dimensional imaging in medicine -- Mathematical models. ; Stereoencephalotomy.
- In the past, clinicians skilled at image-guided neurosurgery have relied solely on pre-operative scans for their navigational information. Often in the course of surgery, tissue is purposely retracted/resected or inadvertently moved resulting in a...
- Dartmouth Dissertations
- Innate immune mechanisms contributing to LP-BM5 murine retroviral pathogenesis and immunodeficiency / by Megan Ashley O''Connor
- LP-BM5 murine retroviral infection induces murine AIDS (MAIDS), and is characterized by profound and broad immunosuppression of T- and B-cell responses. Adaptive immune response to LP-BM5 infection, including the pathogenic role of CD4+ T-cells and...
- Dartmouth Dissertations
- Investigation of the ISG15 deisgylase UBP43 in carcinogenesis : tumor suppressor or oncogene? / by Fadzai Chinyengetere.
- ISGylation is a type 1 interferon-regulated process that involves conjugation of ISG15, an ubiquitin-like protein, to target proteins. This posttranslational modification is reversed by a deubiquitinase known as UBP43 or USP18. UBP43 is deregulated...
- Dartmouth Dissertations
- Negative regulation of IFN-γ responses by TGF-β1 in CD4⁺ T cells: involvement of protein tyrosine phosphatase SHP-1 and MAPK ERK.
- Transforming growth factors-beta. Th1 cells. Interferon. T cells. Protein-tyrosine phosphatase. Mitogen-activated protein kinases. CD4-Positive T-Lymphocytes -- immunology. MAP Kinase Signaling System.
- Dartmouth Dissertations
- Neuronal interferon signaling : implications for HSV-1 replication and pathogenesis / by Pamela Rosato
- Herpes simplex virus-1 (HSV-1) establishes lifelong latent infections in the sensory neurons of the trigeminal ganglia (TG) wherein it retains the capacity to reactivate. The interferon (IFN)-driven antiviral response is critical for the control of...
- Dartmouth Dissertations
- Regulation of dendritic cell functions by human uterine epithelial cells: Implications for HIV-1 infection of the endometrium.
- Dendritic cells. Uterus -- Immunology. Epithelium -- Immunology. Epithelial cells. HIV infections -- Molecular aspects.
- The human female reproductive tract (FRT) maintains a state of immune tolerance to spermatozoa and fetal allografts, while retaining the capacity to respond to a number of sexually transmitted infections (STIs) including human immunodeficiecy virus...
- Dartmouth Dissertations
- Development of a multi-high frequency electrical impedance tomography system for breast imaging.
- Electrical impedance tomography. Breast -- Imaging. Imaging systems -- Design and construction.
- Dartmouth Dissertations
- Regulation of B lymphocyte proliferation and differentiation through CD40.
- B cells. CD antigens. Immune response -- Regulation.
- Dartmouth Dissertations
- Post-translational modification in retinoid action: a role for UBEIL in cancer therapy and chemoprevention.
- Retinoids -- Mechanism of action. ; Post-translational modification. ; Tretinoin -- Therapeutic use. ; Lungs -- Cancer -- Chemoprevention.
- The retinoids--natural and synthetic derivatives of vitamin A--are active in cancer therapy and chemoprevention. The signals that underlie retinoid clinical activity are triggered by induction of retinoid target genes. Therefore, a greater...
- Dartmouth Dissertations
- Recursion theory in fragments of arithmetic.
- Recursion theory. ; Logic Symbolic and mathematical.
- Dartmouth Dissertations
- Potential theory for geometrically ergodic infinite interacting particle systems.
- Ergodic theory.
- Dartmouth Dissertations
- Characterizing Siegel modular forms.
- Forms, Modular. ; Siegel domains.
- Dartmouth Dissertations
- Thermodynamic and spectroscopic studies of metal binding properties of histidine-rich peptides and proteins.
- Histidine. ; Peptides -- Analysis. ; Proteins -- Analysis. ; Metal ions. ; Binding sites (Biochemistry) -- Thermodynamics. ; Macromolecules -- Spectra. ; Thermometric titration. ; Calorimetry. ; Electron paramagnetic resonance spectroscopy.
- Dartmouth Dissertations

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