Dartmouth Digital Library Program

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Sulfate reduction, nutrient limitation, and reactor design considerations in anaerobic digesters.
Anaerobic bacteria -- Industrial applications. ; Sewage sludge digestion. ; Sulfates. ; Autoclaves.
Dartmouth Dissertations

Pattern avoiding permutations & rook placements / by Jonathan S. Bloom.
In Chapter 2 we look at the distribution of permutation statistics in the context of pattern-avoiding permutations. The first part of this chapter deals with a recursively defined bijection of Robertson [37] between 123- and 132-avoiding...
Dartmouth Dissertations

Experiment planning for protein structure elucidation and site-directed protein recombination.
Proteins -- Structure -- Computer simulation -- Experiments. ; Amino acid sequence -- Data processing -- Experiments. Protein engineering -- Experiments. ; Recombinant proteins -- Mathematical models.
In order to most effectively investigate protein structure and improve protein function, it is necessary to carefully plan appropriate experiments. The combinatorial number of possible experiment plans demands effective criteria and efficient...
Dartmouth Dissertations

Capture time in variants of cops & robbers games / by Natasha Komarov.
We examine variations of cops and robbers games on graphs. Our goals are to introduce some randomness into their study, and to estimate (expected) capture time. We show that a cop chasing a random walker can capture him in expected time n + o(n)....
Dartmouth Dissertations

Combined MRI and near-infrared spectroscopy for increased specificity of breast cancer imaging / by Michael A. Mastanduno.
A yearly breast contrast-MR scan is recommended to high-risk women because of MR's high sensitivity to breast tumors. However, breast contrast-MR yields a high number of false positives that lead to expensive and sometimes unnecessary biopsy...
Dartmouth Dissertations

Combined digital breast tomosynthesis and near-infrared spectral tomography for breast lesion characterization / by Kelly E. Michaelsen.
Annual screening mammograms are recommended for all women above 40 years of age for early detection of breast cancer, and are known to improve cancer mortality rates. However, mammography is hampered by low sensitivity and a high rate of false...
Dartmouth Dissertations

Geology of the Lake Atitlan area, Guatemala : a study of subduction zone volcanism and caldera formation.
Geology -- Guatemala -- Lake Atitlan area; Volcanism -- Guatemala -- Lake Atitlan area; Calderas -- Guatemala -- Lake Atitlan area.
Geological mapping, petrological and geophysical studies in the lake Atitlan area, Guatemala, have revealed four distinct periods of stratovolcano growth, each followed by major silicic eruptions and caldera collapse. The first period (12 - 11 my...
Dartmouth Dissertations

A generalized least-squares minimization method for near infrared diffuse optical tomography.
Optical tomography. ; Near infrared spectroscopy. ; Image analysis -- Mathematical models. ; Imaging systems -- Image quality -- Mathematical models. ; Image reconstruction -- Mathematical models. ; Least squares. Breast -- Tomography.
Diffuse optical tomography (DOT) has the potential to become a non-invasive and non-ionizing diagnostic imaging technique for breast cancer imaging. DOT uses near-infrared (NIR) light to illuminate the breast, generally through the use of fiber...
Dartmouth Dissertations

Microwave tomographic imaging using dielectric contrast in temperature and tissue content
Breast -- Cancer -- Tomography. ; Breast -- Cancer -- Imaging. ; Microwave imaging in medicine. ; Breast -- Electric properties. ; Breast Neoplasms -- diagnosis. ; Diagnostic Imaging -- methods.
Dartmouth Dissertations

Innate immune mechanisms contributing to LP-BM5 murine retroviral pathogenesis and immunodeficiency / by Megan Ashley O''Connor
LP-BM5 murine retroviral infection induces murine AIDS (MAIDS), and is characterized by profound and broad immunosuppression of T- and B-cell responses. Adaptive immune response to LP-BM5 infection, including the pathogenic role of CD4+ T-cells and...
Dartmouth Dissertations

Altered serotonin signaling impairs cardiorespiratory control in early postnatal development : relevance for the SIDS / by Karlene T. Barrett.
Serotonin -- Receptors.;""Serotoninergic mechanisms -- Sudden infant death syndrome -- Pathogenesis -- Respiration -- Regulation -- Medulla oblongata -- Physiology.""
Dartmouth Dissertations

Approximate identities and multipliers of Banach algebras
Banach algebras.; Banach spaces.
Dartmouth Dissertations

In vivo degradation in modern orthopaedic UHMWPE bearings and structural characterization of a novel alternative UHMWPE material / by Steven D. Reinitz.
Ultra-high molecular weight polyethylene (UHMWPE) remains the most common bearing material for total joint arthroplasty. Advances in radiation cross-linking and other post-consolidation treatments have led to a rapid differentiation of polyethylene...
Dartmouth Dissertations

The causes and consequences of regulation of [Delta]NP63[alpha] in mammary and breast cancer stem cells / by Andrew Joseph DeCastro.
Despite the array of targeted therapeutics that currently exist to combat breast cancer, disease progression leading to metastasis, and tumor recurrence still remains a significant clinical challenge. Efforts to identify novel pathways and...
Dartmouth Dissertations

Smith-Purcell radiation from relativisitc electrons: theory and experiment.
Electrons -- Diffraction. Diffraction gratings -- Experiments. Quantum electrodynamics.
Dartmouth Dissertations

Microwave imaging for 2-D electrical property distribution profiling.
Image reconstruction. Microwave imaging. Microwave imaging -- Instruments -- Design and construction. Microwave imaging in medicine.
Dartmouth Dissertations

Computer modeling of total hip replacement : application to joint geometry stress analysis and bone remodeling
Total hip replacement -- Computer simulation.
Dartmouth Dissertations

Induced optical effects in germanium-doped silica glass.
Silica, Vitreous -- Optical properties.
Dartmouth Dissertations

On the poisson relation for lens spaces / by Donato R. Cianci
Motivated by quantum mechanics and geometric optics, it is a long-standing problem whether the length spectrum of a compact Riemannian manifold can be recovered from its Laplace spectrum. One route to proving that the length spectrum depends on the...
Dartmouth Dissertations

Sounding-rocket studies of Langmuir-wave microphysics in the auroral ionosphere / by Micah P. Dombrowski
Since their discovery in laboratory plasmas in the 1920s, Langmuir waves have been observed to be ubiquitous in plasma environments, particularly in space plasmas. From the greater solar wind to planetary foreshocks and the auroral ionosphere,...
Dartmouth Dissertations

On the origins of cancer cell identity : epigenetic deregulation of cellular states / by Kevin Johnson
The identification of molecular alterations present in cancer is critical to better understand carcinogenesis as well as the clinical trajectories of patients with malignant tumors. Early detection and application of appropriate treatment...
Dartmouth Dissertations

Novel synthetic approaches to polycyclic aromatic hydrocarbons.
Polycyclic aromatic hydrocarbons -- Synthesis.
This research attempts to combine known methodology with new chemistry towards the preparation of extended polycyclic aromatic hydrocarbons (PAH). The generation and Diels-Alder trapping of 1,7- and 2,6-naphthalene bisarynes was attempted for the...
Dartmouth Dissertations

Analysis of the respiratory movements of the human vocal cords.
Vocal cords. ; Respiration.
Dartmouth Dissertations

Vibrio cholerae pathogenesis: molecular mechanisms of colonization.
Vibrio cholerae -- Molecular genetics. ; Bacteria -- Adhesion. ; Virulence (Microbiology). ; Cholera -- Pathogenesis. ; Pili (Microbiology).
Vibrio cholerae is a gram-negative bacterial pathogen that causes the severe diarrheal disease cholera. Several bacterial factors have been identified that are critical for V. cholerae intestinal colonization. The best characterized of these...
Dartmouth Dissertations

Synthesis and bond alternation of azulene derivatives.
Azulene -- Derivatives -- Synthesis. ; Polycyclic aromatic hydrocarbons -- Synthesis. ; Crystallography. ; Chemical bonds.
5,6-Azulyne, the first azulyne to be prepared, has been trapped with furan to give an adduct whose crystal structure reveals marked bond alternation in the azulene pi system. The double bond in the furan moiety is responsible in part for the bond...
Dartmouth Dissertations

Spectroscopic reconstructed near infrared tomographic imaging for breast cancer diagnosis.
Breast -- Cancer -- Tomography. ; Breast -- Cancer -- Imaging. ; Breast -- Cancer -- Diagnosis. ; Near infrared reflectance spectroscopy. ; Image processing -- Digital techniques.
Near-infrared (NIR) light has the potential to be used as a non-invasive means of diagnostic imaging within the human breast. Due to the diffusive nature of light in tissue, computational model-based methods are required for functional imaging...
Dartmouth Dissertations

Sex- and region-specific differences in GABA[subscript A] receptor function in neurons of the hypothalamus and forebrain.
GABA -- Receptors. ; GABA -- Physiological effect. ; Sexual behavior in animals. ; Hypothalamus -- Physiology.
The overall goal of this research has been to investigate sex-specific and region-specific differences in the function of the γ-aminobutyric acid type A (GABA[subscript A]) receptor in two regions of the brain which are essential for the...
Dartmouth Dissertations

Investigation, optimization and synthesis of dihydrodipyrrins, linear tetrapyrroles and the resulting chlorins.
Porphyrins -- Synthesis. Tetrapyrroles -- Synthesis.
The synthesis of macrocyclic tetrapyrroles continues to be an area of vigorous research due to their application to a wide range of fields spanning the physical sciences. Only recently have general syntheses for the reduced systems, such as...
Dartmouth Dissertations

Transformation monoids of algebraic number rings.
Monoids. ; Transformations (Mathematics). ; Rings (Algebra). ; Galois theory.
Dartmouth Dissertations

Computer analysis and design of building frames.
Structural design. ; Airplanes -- Design and construction. ; Airplanes -- Data processing.
Dartmouth Dissertations

Computational studies of small group IB clusters and their van der Waals complexes.
Transition metal complexes -- Spectra. ; Chemical reaction.
Dartmouth Dissertations

Large bowel polyps: aspects of epidemiology and diagnosis.
Intestine, Large -- Cancer -- Epidemiology. ; Intestine.
Colorectal cancer is the fourth most common cancer diagnosis and the second leading cause of cancer-related death in the United States. Most colorectal cancers are believed to develop from precursor lesions known as colorectal adenomas....
Dartmouth Dissertations

Analysis of inpatient surveillance data for automated classification of deterioration.
Problem Statement Patient safety in the modern hospital is supported by multiple human and technological systems, and this type of high-risk/high-complexity domain requires multiple layers of protection against harm. This fault-tolerant approach is...
Dartmouth Dissertations

Magnetic resonance poroelastography.
Brain -- Magnetic resonance imaging -- Mathematical models. Brain -- Mechanical properties -- Mathematical models. Elasticity -- Mathematical models.
Magnetic Resonance Elastography (MRE) has emerged as a noninvasive, quantitative physical examination of the elastic properties of soft biological tissues including breast, liver, prostate, and brain. Implementation of constitutive relations that...
Dartmouth Dissertations

Discovery of new NAD+ metabolic pathways and nutritional regulation.
NAD (Coenzyme) -- Metabolism. Nicotinamide -- Mechanism of action. Phosphatases. Phosphates -- Metabolism -- Regulation. Medical Term Nucleotidases -- metabolism. Nicotinamide-beta-riboside.
Nicotinamide adenine dinucleotide (NAD+) is classically known as an essential co-enzyme for hydride transfer reactions in metabolism. More recently, it has been recognized as a consumed substrate of ADPribose transfer enzymes...
Dartmouth Dissertations

Algebras counting self-intersections of curves
Goldman and Turaev constructed a Lie bialgebra structure on the free Z-module generated by free homotopy classes of loops on an oriented surface. Turaev conjectured that the cobracket of A is zero if and only if A is a power of a simple class. Chas...
Dartmouth Dissertations

The regulation and packaging of Cif, a novel virulence factor of Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen of humans and the leading cause of mortality in patients with the inherited disorder cystic fibrosis (CF). The focus of the studies presented herein was characterization of the regulation and...
Dartmouth Dissertations

Selective serotonergic modulation of cortical pyramidal neurons in the rodent prefrontal cortex / by Daniel Avesar.
Serotonin (5-hydroxytryptamine, 5-HT) in the prefrontal cortex (PFC) plays an important role in cognitive processing and emotional regulation, and altered serotonergic signaling in the cortex is associated with disorders such as schizophrenia,...
Dartmouth Dissertations

Innate immune responses to HIV-1 and Chlamydia trachomatis in the human female reproductive tract / by Lucy Rudo Mukura.
Female reproductive tract (FRT) secretions contain a spectrum of cytokines, chemokines and antimicrobials that inhibit infection of target cells by HIV-1 and other sexually transmitted pathogens. Innate immune protection maintained by the presence...
Dartmouth Dissertations

Lacrosse Teams
Lacrosse Teams
Dartmouth College Varsity Lacrosse 1952-1953 Front Row: Malin, RA '53 (Manager), Learnard, HH II '53, Jacob, CH Jr '53, Bloomer, TD '53 (Captain), Fenton, PS '53, Sanderson, SA '53, Fauver, SL '53 Second Row: Gilbody, J. (Trainer), Gates, RC '54,...
Dartmouth College Photographic Files

Swimming Teams 1
Swimming Teams 1
Varsity Swimming 1959-1960 Front Row: Piper, WS '61, Brown, CM '61, Dunphy, WW '61, Prior, JR '60, Growney, EM '58, Travis, JT (Capt) '60, Raber, CF '60, Hale, AN '61, Baker, DS '61, Carney, CE '61, Gemelli, GG '61. Second Row: Michael, KB (Coach),...
Dartmouth College Photographic Files

Thayer School Students 1940s-1950s
Thayer School Students 1940s-1950s
First row (l to r) WJ Cairns, WH Miller, RM Mauk, DD Bursch, RB Krom, HW Graves Second row (l to r) Prof Sherrard, Prof Brown, Prof Ermenc, Dean Kimball, JO Foote, JA Conners, RM McIlwain Prot Hatch, Prof Minnich, Mr Goldthwaite Third row (l to r)...
Dartmouth College Photographic Files

Understanding the vulnerabilities of tumors : a network-based approach to drug target discovery / by Nadia M. Penrod.
The demand for novel molecularly targeted drugs will continue to rise as we make progress toward personalizing cancer treatments to the molecular signatures of individual tumors. While the collection and analysis of genomic data has become routine,...
Dartmouth Dissertations

MicroRNA-10b promotes pancreatic cancer cell invasion by suppressing TIP30 and enhancing EGF and TGF-[beta] actions / by Haoxu Ouyang
MicroRNA-10b (miR-10b) is considered a marker of disease aggressiveness in pancreatic ductal adenocarcinoma (PDAC), in view of the fact that lower levels of miR-10b are associated with better response to neoadjuvant therapy, likelihood of surgical...
Dartmouth Dissertations

Magnetic nanoparticle hyperthermia as an adjuvant cancer therapy with chemotherapy / by Alicia Ailie Petryk.
Magnetic nanoparticle-based hyperthermia for cancer treatment is a promising technology, particularly when applied as part of an adjuvant strategy with established cancer therapies (chemotherapy, radiation and surgery). In Europe, early clinical...
Dartmouth Dissertations

Simultaneous saccharification and co-fermentation of paper sludge.
Cellulose -- Biodegradation. Zymomonas mobilis -- Biotechnology. Saccharomyces cerevisiae -- Biotechnology. Fermentation. Hydrolysis. Biomass conversion -- Mathematical models.
Production of fuel ethanol from cellulosic materials is a potentially attractive way to meet sustainability, energy security, and environmental goals. However, the high cost of processing using current technology has thus far prevented...
Dartmouth Dissertations

Alterations in the production of bacteriochlorophyll a and okenone in purple sulfur bacteria : implications for the interpretaion of their biomarkers / by Derek A. Smith.
Purple sulfur bacteria (PSB) can dominate the nitrogen, carbon, and sulfur cycles in anoxic ecosystems via their anoxygenic photosynthetic metabolisms and are the only producers of the carotenoid, okenone, a biomarker targeted for photic zone...
Dartmouth Dissertations

Brain repair after trauma : birth and migration of immature neurons after focal traumatic brain injury in piglets and human children / by Sabrina Rose Taylor.
Traumatic brain injury (TBI) is the leading cause of acquired disability in children, yet innate repair mechanisms are incompletely understood. A possible innate mechanism to repair injury after insult is neurogenesis - the birth, migration,...
Dartmouth Dissertations

Characterization of the role of Bacillithiol in Staphylococcus aureus / by Ana Catalina Posada.
As methicillin-resistant Staphylococcus aureus (MRSA) hospitalizations keep increasing, the understanding of the characteristics that make one isolate more successful over another is paramount. Strain variations among Staphylococcus aureus observed...
Dartmouth Dissertations

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