We present aligned hierarchies, a novel solution to the dimension reduction problem, representing high-dimensional and noisy sequential data as a low-dimensional object that encodes relevant information. In this thesis, we motivate our presentation...
Electronic data processing -- Distributed processing. ; Computer network architectures. ; Programming languages (Electronic computers) -- Semantics. ; Database management.
I tackle the problem of naming and sharing resources across administrative boundaries. Conventional systems manifest the hierarchy of typical administrative structure in the structure of their own mechanism. While natural for communication that...
Home care services -- Utilization -- New Hampshire. Home care services -- New Hampshire -- Evaluation. Maternal health services -- Utilization -- New Hampshire. Infant health services -- Utilization -- New Hampshire. Prenatal care -- Utilization --...
Research objective . Research suggests that home visiting services can have a significant impact on pregnancy outcomes, child health and development, parenting and maternal life course. The effect of home visiting on utilization of health services...
Given graded C *-algebras A and B , we define the notion of an admissible pair ([straight phi], D ) for A and B . Associated to an admissible pair ([straight phi], D ) is an equivalence class of asymptotic morphisms from A to B . Under certain...
This thesis constitutes the first steps in the author's program to investigate the question of when a homotopy of 2-cocycles ω = {ω[subscript t]}[subscript t∊[0,1]] on a locally compact Hausdorff groupoid Ɠ induces an isomorphism of the...
The problem of moving rigid bodies efficiently is of particular interest in robotics because the simplest model of a mobile robot or of a manipulated object is often a rigid body. Path planning, controller design and robot design may all benefit...
This thesis reports work on a new device to detect changes in spatially nonuniform intensity distributions, and shows how this device can be applied to the particular problem of optical vibration detection. The phase of optical radiation is very...
Nuclear magnetic resonance spectroscopy -- Data processing. ; Proteins -- Analysis -- Mathematical models. ; Computer algorithms.
Our aim is to enhance high-throughput applications of Nuclear Magnetic Resonance (NMR) through the development of efficient computational methods that operate on sparse (minimal) sets of experimental NMR data. We have developed a family of four...
The focus of this thesis is the study of nuclearity and exactness for groupoid crossed product C*-algebras. In particular, we present generalizations of two well-known facts from group dynamical systems and crossed products to the groupoid setting....
Advances in medicine such as organ transplantations and cancer therapies involve the use of immunosuppressant drugs have led to rises in at risk patients and invasive fungal infections (IFIs). The filamentous fungus Aspergillus fumigatus is the...
Quantitative Risk Analysis of Computer Networks (QSRA) addresses the problem of risk opacity of software in networks. It allows risk managers to get a detailed and comprehensive snapshot of the constitutive software on the network, assess its risk...
'The control of waves using periodic structures is crucial for modern optical, electromagnetic and acoustic devices such as diffraction gratings, filters, photonic crystals, solar cells, sensors, and absorbers. We present a high-order accurate...
Chlorinated ethenes are ubiquitous environmental pollutants of public concern due to their potential toxicity and carcinogenicity. Under appropriate conditions anaerobic bacteria mediate the dechlorination of perchloroethylene (a common dry...
A fiber can transmit around 25 Tbit/s, but electronic signal processing today is performed at much slower speeds, usually 1-10 Gbit/s. To avoid this "bottleneck" in optical fiber communication systems, all signal processing will have to be done...
Three-dimensional imaging in medicine -- Mathematical models. ; Stereoencephalotomy.
In the past, clinicians skilled at image-guided neurosurgery have relied solely on pre-operative scans for their navigational information. Often in the course of surgery, tissue is purposely retracted/resected or inadvertently moved resulting in a...
The motivational and rewarding properties of our immediate environment affect how humans interact with our world in a number of ways. One important aspect in which reward representation shapes behavior is in the development, maintenance and...
Plant MADS proteins play critical roles in vegetative and reproductive development. DNA binding and yeast three-hybrid assays suggest that plant MADS proteins function as dimers or multimers. However, little is known about how plant MADS proteins...
Previous studies have shown that the mucosal immune system is present in the female reproductive tract and under hormonal control. With the recognition that underlying stromal cells regulate epithelial cell function and hormonal responsiveness,...
Snow -- Permeability. ; Snow surveys -- Antarctica -- East Antarctica. ; Surfaces -- Areas and volumes. ; Gas flow. ; Porosity.
Recent field investigations of a megadunes region of East Antarctica provide evidence that differences in grain size, thermal conductivity, and permeability across a megadune are due to relative accumulation patterns in the absence of significant...
Nurses -- Health and hygiene. Employee health promotion.
Background. Worksite health promotion programs (HPP) support employees' health behaviors to prevent downstream diseases. Maximizing participation can optimize program impact. Objectives. To assess staff nurses' participation in three HPP - flu...
For a long-lived metastable system, the decay of the survival probability is typically exponential. However, deviations are known to exist at short times (the quantum Zeno effect) and at long times (algebraic tails in classical hydrodynamic...
Little is known about the emergence of life from nonliving precursors. A key missing- piece is the origin of homochirality: nearly all life is characterized by exclusively dextrorotary sugars and levorotary amino acids. The research presented in...
Ovaries -- Cancer -- Immunotherapy. Dendritic cells. Small interfering RNA. Nanoparticles -- Therapeutic use. Medical Term Ovarian Neoplasms -- therapy. RNA Interference.
Current therapies for ovarian carcinoma are based on surgical debulking followed by chemotherapy. After more than three decades implementing treatments that selectively target the tumor cell, the 5-year survival rate for metastatic ovarian cancer...
This thesis focuses on the emergence of universal dynamical scaling in quantum critical spin systems driven out of equilibrium, with emphasis on quench dynamics which involves isolated standard critical points, multi-critical points, and...
This thesis investigates the embedding theory of orders in central simple algebras, placing a particular emphasis on the role that the phenomenon known as selectivity plays in the theory. Although the notion of selectivity is completely algebraic,...
The ionosphere is an important source of plasma in the magnetosphere, especially during geomagnetic storms. While satellite data has confirmed this population of ions, their effect on the dynamics of the magnetosphere-ionosphere (MI) system is not...
Pseudomonas aeruginosa is an opportunistic pathogen of humans and the leading cause of mortality in patients with the inherited disorder cystic fibrosis (CF). The focus of the studies presented herein was characterization of the regulation and...
Serotonin (5-hydroxytryptamine, 5-HT) in the prefrontal cortex (PFC) plays an important role in cognitive processing and emotional regulation, and altered serotonergic signaling in the cortex is associated with disorders such as schizophrenia,...
The demand for novel molecularly targeted drugs will continue to rise as we make progress toward personalizing cancer treatments to the molecular signatures of individual tumors. While the collection and analysis of genomic data has become routine,...
Accurate chromosome segregation in human oocytes requires that meiotic sister chromatid cohesion remain intact for decades and work in model organisms indicates that deterioration of meiotic cohesion over time may be a major determinant of...
Production of fuel ethanol from cellulosic materials is a potentially attractive way to meet sustainability, energy security, and environmental goals. However, the high cost of processing using current technology has thus far prevented...