Protein kinase C activators and microtubule damaging drugs stimulate BCL2 phosphorylation, which has been associated with either enhancement or inhibition of cell viability. In a Burkitt lymphoma cell line, both types of agents likewise stimulated...
Digital cinematography. ; Cinematography -- Lighting -- Data processing -- Evaluation. ; Cinematography -- Special effects -- Data processing -- Evaluation. ; User interfaces (Computer systems) -- Evaluation.
We define appearance design as the creation and editing of scene content such as lighting and surface materials in computer graphics. The appearance design process takes a significant amount of time relative to other production tasks and poses...
Evolutionary Computation (EC) is one of the most advanced computational techniques. It has been frequently and successfully used to find good solutions to many complicated optimization problems with limited computational resources. EC is the...
The data presented herein demonstrate the requirement for CD154/CD40 in the development of experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis. Blockade of CD154/CD40 interactions causes a decrease in T cell and...
Metalorganic chemical vapor deposition (MOCVD) is a complex process. In this thesis, we try to understand the formation mechanism of cadmium (Cd) and cadmium sulfide (CdS) thin films by MOCVD. CdS can be formed from the spontaneous reaction of...
The field of proteomics aims to identify and quantify the protein contents of a biological sample. The mass spectrometer is the instrument of choice to characterize these proteins. In the typical proteomics experiment, mass spectra are collected...
Sponges are a historically ambiguous taxon, often considered primitively simple representatives of early Metazoa, living fossils from the era before the complex morphological features of the bilaterian phyla appeared in the Cambrian. Yet recent...
MicroRNA-10b (miR-10b) is considered a marker of disease aggressiveness in pancreatic ductal adenocarcinoma (PDAC), in view of the fact that lower levels of miR-10b are associated with better response to neoadjuvant therapy, likelihood of surgical...
Aberrant activation of cyclin D-Cdk4/6 is commonly found in pancreatic ductal adenocarcinoma (PDAC). Here, we show that PD-0332991, a highly specific inhibitor for Cdk4 and Cdk6, exerted growth inhibitory effects on human PDAC cell lines....
RNA binding proteins are fundamental components of crucial biological processes in all domains of life. The development of techniques to study RNA binding protein complexes is, therefore, broadly impactful. I employed multiple genome-wide...
Liver disease of different etiologies confers significant morbidity and mortality and hence it constitutes a major health concern worldwide. Stemming from a range of causes, such as viral, drug-induced, alcoholic, or autoimmune, the rate of...