This thesis investigates the embedding theory of orders in central simple algebras, placing a particular emphasis on the role that the phenomenon known as selectivity plays in the theory. Although the notion of selectivity is completely algebraic,...
Formins are actin nucleators that modulate the nucleation and elongation of actin filaments. Formin homology 1 (FH1) and formin homology 2 (FH2) domains play a key role in formin-mediated actin dynamics. INF2 is a unique formin which can both...
The Border Gateway Protocol (BGP) that manages inter-domain routing on the Internet lacks security. Protective measures using public key cryptography introduce complexities and costs. To support authentication and other security functionality in...
Both human epidemiological and animal studies have associated inhalation of chromium(VI) (Cr(VI)) with increased incidence of pulmonary disease. This thesis examined the hypotheses that Cr(VI) activates cell signaling through kinase cascades and...
Sensor networks are used in many realtime applications for collecting information from monitored environments and objects, such as moving vehicle tracking, battlefield reconnaissance, and habitat monitoring. Sensor networks are often deployed in...
I present new wide-field photometry of several globular clusters including: BVI ground-based photometry and VI space-based photometry for the globular cluster M92 (NGC 6341) BVI photometry for M2 (NGC 7089), M3 (NGC 5272), and M14 (NGC 6402) and...
One of the important challenges facing image-guided neurosurgery is the fact that the brain deforms significantly over the course of an operation during open-cranial procedures. This results in a loss of registration between the brain and the...
Cataclysmic variable stars (CVs) are close, interacting binary systems comprised of a white dwarf and a companion star, which is typically a late-type dwarf star. Their progenitor systems are post common envelope binaries (PCEBs) with a white dwarf...
Genetic and immunological tools have been used to study two protozoan parasites, Plasmodium falciparum and Toxoplasma gondii. Toxoplasma gondii provides an excellent model for the study of protozoan parasite biology. Plasmodium falciparum causes...
Three-dimensional imaging in medicine -- Mathematical models. Intraoperative monitoring. Cerebral cortex -- Imaging. Computer vision. Space perception.
Brain deformation models have proven to be a powerful tool in compensating for soft tissue deformation during image-guided neurosurgery. The accuracy of these models can be improved by incorporating intraoperative measurements of brain motion. We...
A 62 kDa (p62) mitotic apparatus-associated protein has been shown to be important for the proper progression of mitosis in sea urchin embryos. The thesis project described here focuses on an immunological and a molecular characterization of p62....
Cellulase -- Biotechnology. ; Hydrolysis. ; Paper industry -- Technological innovations. ; Biomass energy -- Economic aspects. ; Saccharomyces cerevisiae -- Genetics. ; Enzymes -- Industrial applications.
Paper sludge is the largest solid waste stream produced by pulp and paper industry, and is also an attractive feedstock for emergent technologies based on processing of cellulosic biomass featuring enzymatic hydrolysis. This study focuses on...
Light scattering from tissue originates from the fluctuations in intra-cellular and extra-cellular components, so it is possible that macroscopic scattering spectroscopy could be used to quantify sub-microscopic structures. Both electron microscopy...
This dissertation details the use of a new catalog of Galactic bulge field RR Lyrae variables to advance the understanding of the structure of the Milky Way Galaxy. The catalog contains 3667 RR0 Lyrae stars from the eight-year MACHO Project...
Chromatin -- Structure. DNA -- Methylation. Globin genes -- Expression. Adenosine triphosphatase. Proteins -- Chemical modification.
Epigenetic regulation of gene expression is a developing field of study with many potential therapeutic applications. Chromatin remodeling is necessary for proper mammalian development, and misregulation of this process is associated with many...
Though the science of invasion biology has over a 50-year history it still struggles with clearly documenting the mechanisms and impacts of plant invasions. Numerous observational studies find associations between plant invasions and largescale...
Accurate segregation of meiotic chromosomes requires that sister-chromatids remain physically associated from the time of their synthesis during S phase until they segregate toward opposite poles at anaphase II. In Drosophila melanogaster meiosis,...
Diagnostic imaging -- Mathematics. Expectation-maximization algorithms. Imaging systems in medicine -- Mathematics.
We have developed a general-purpose registration algorithm for medical images and volumes. The transformation between images is modeled as locally affine but globally smooth, and explicitly accounts for local and global variations in image...
Molecular optical imaging in vivo has potential for functional assessment of tumor tissue at the cellular and subcellular level. Advances in biological understanding of genomics and proteomics have increased the knowledge of possible cellular...
We present new forensic tools that are capable of detecting traces of tampering in digital images without the use of watermarks or specialized hardware. These tools operate under the assumption that images contain natural properties from a variety...
Constructibility (Set theory). Trees (Graph theory).
This thesis investigates possible initial segments of the degrees of constructibility. Specifically, we completely characterize the structure of degrees in generic extensions of the constructible universe L via forcing with Souslin trees. Then we...
Casimir effect. Zero-point field. Electric conductivity. Quantum electrodynamics.
The Casimir force arises from an alteration of boundary condition in vacuum and is often regarded as a manifestation of quantum zero point energy. Considerable progress has been made in the last decade with an impressive achievement of experimental...
Nerve growth factor (NGF), the prototypic neurotrophin, is well characterized for its pro-survival and growth effects in sympathetic and sensory neurons. Acting as a target-derived factor, NGF regulates the maturation of innervating neurons, and...
The Greenland Ice Sheet (GrIS) is responding sensitively to climate change and its meltwater has the potential to influence global sea level. Recently, large changes in the GrIS have occurred including increased velocities of outlet glaciers and...
In this thesis, we consider several problems relating to cyclic subgroups of the group [mathematical equation]. Each element of [mathematical equation] has a unique representative in one of the two intervals [mathematical equation] and...
Chemical sensing and separation is a constant challenge intriguing many scientists. Through numerous efforts, revolutionary techniques and innovative materials have been successfully developed to solve this old problem. However, a practical but...
Digital integrated circuits -- Testing. Digital integrated circuits -- Testing -- Mathematical models. Digital integrated circuits -- Design and construction.
Fir waves are spatially and temporally repeating patterns of stand development and destruction in subalpine, balsam fir-dominated forests of the northeastern United States, perpetuated by downwind migration of strips of dying trees, "dieback...