Mitomycin C -- Mechanism of action. ; DNA -- Effect of mitomycin C on. ; Genetic expression -- Effect of mitomycin C on. ; DNA-protein interactions -- Effect of mitomycin C on.
Mitomycin C (MMC) is a chemotherapeutic drug that reacts with the N$\sp2$ of guanine to form monoadducts, interstrand and intrastrand crosslinks. These lesions, especially the interstrand crosslink, are believed to be responsible for the potent...
Mitomycin C -- Genetic aspects. ; DNA damage. ; Drug resistance in cancer cells. ; Cancer -- Chemotherapy -- Genetic aspects.
Our laboratory is concerned whether the distribution of chemically-induced DNA damage is non-random at the level of individual genes. Using changes in gene expression as a marker for DNA damage, we have previously demonstrated that genotoxic...
Football Teams 1950s-Present; 1963 team; Jack McLean; Bob O'Brien; SCott Creelman; Dave Lawson; Tom Spangenberg; 3 names written on players, unreadable; photo by David Pierce Studio, Hanover, New Hampshire
Lacrosse Teams Freshman, 1967; Class of 1970; Front row; left to right: O'Neill, D. R.; Church, G. S.; DeVan. L. S.; King, R. S.; Young, L. A., III; Dorkey, C. E., III; McLean, A. C.; Sammis, R. C.; Babcock, E. J.; Warren, T. S.; Second row: Oakes,...
Delta Kappa Epsilon Members 1; Delta Kappa Epsilon Pi Chapter 1887-1888; 1. Hanson, G. M. '90; 2. Carpenter, H. S. '88; 3. Blakely, G. S. '88; 4. DuBois, C. G. '91; 5. Richardson, D. C. '91; 6. Lord, E. T. S. '91; 7. Gilman, B. S. '91; 8. Allen, F....
Vibrio cholerae is the etiologic agent of cholera in humans. Intestinal colonization occurs via ingestion of contaminated food and water and results in symptoms that include the production of the characteristic rice water stool, vomiting, and...
The previously synthesized 3,4-dibromo-8-oxabicyclo[3.2.1]octa-3,6-dien-2-one has been shown to be a very versatile building block for the synthesis of complex natural product structures. This key building block has been made in both...
A variety of forensic methods have been developed to identify falsified photos, each unified by the ability to estimate and detect properties of a photo that are perturbed by forgery. There exist, however, many photos in which the required...
1968-69 Dartmouth Varsity Basketball Team Front row , left to right: Randy Quayle; Cleve Penberthy; Jerry O'Brien, Captain; Greg Pickering, Van McQueen; Joe Cook; Tom Reddy; Middle row: John Ryzewic, Dave Howell; Gunnar Klintberg; Karl Steinmanis;...
Organic Farm p3; Please Credit: Stuart Bratesman / Dartmouth College (c) 1991 Dartmouth College; Justin Rendahl, David O'Brien, Christian Kull, Jennifer Jenkins, John Decker, (with pitchfork), Steve Sloan; Colin J. High
Founders of Camp William James met last summer for the first time since the esperimenatl Tunbridge, Vt., camp closed in 1942. From left: Robert O'Brien '40, Clinton Gardner '44, Edwin Luce, William Uptegrove '42, Louis Schlivek '40, Charles Dell...
Photograph taken in Hanover, 1906. Re-photographed 1937. Walter Powers, D.S Waring, G.N. Bankart, D.C. McIntire, H.W. Rainie, E.G. Pratt, W.P. McGrail, D.J. Main, H.P. Wayman, George Loff, T. Brown, C.T. Gray, Michael J. O'Brien, C.A. Russ.
Left to right: Cleve Spillars Paul O'Brien Ed Oppenheim Dick Shaw Roger Stanwood Member of class of '39 at Oklahoma City Regional Alumni Conference Dec. 8-9, 1960; taken by S.E. Wheelock MD
4/81 DAM issue; Class of 1971 Holds dinner in New York- preparing for a big tenth reunion in June, a group of twenty members of the Class gathered in a New York restaurant. Among those present were, from left to right, Steve Zrike, Charlie Collier,...
Rockford Morning Star, Sunday November 7, 1943 Camp Grant Men Attend "Dartmouth Night" fete These Camp Grant officers and enlisted men were among alumni and former students who paid tribute to their alma mater Friday night during the annual...
The great /34 Delta Kappa Epsilon Delegation; back row, left to right: Ray Hulsart; Jack Dineen; Bob Bennett; Chink Ong; Smitty O'Brien; Rollie Morton; Dick Loughry; Ed Wilson; Jake Edwards; John Foley; middle row: Bill Hartman; Bob Foster; Pat...