Proteins are ubiquitous in cells and are essential to a wide range of biological processes. Since existing proteins occupy only a small portion of the space of possible amino acid composition, understanding their sequence-structure-function...
In this thesis we look at several problems that lie in the intersection between combinatorial and multiplicative number theory. A common theme of many of these problems are estimates for and properties of the smooth numbers, those integers not...
Calanus finmarchicus -- Georges Bank. ; Calanus finmarchicus -- Maine Gulf of. ; Calanus finmarchicus -- North Atlantic Ocean.
Calanus finmarchicus, a kind of marine zooplankton, plays an important ecological role throughout the North Atlantic. Striking seasonal variations exist in its abundance and distribution in the Gulf of Maine/Georges Bank region. On the Bank in...
Autonomous off-road navigation in unstructured, terrain can encounter mobility difficulties even when the surface that the vehicle is driving over is level and free from obstacles. Mobility challenges result from soil characteristics that prevent...
Liver -- Cancer -- Etiology. Hepatotoxicology. Aflatoxins -- Toxicology. Taurine. Liver -- Cancer -- Animal models.
A hypothesis that chronic aflatoxin Bi- (AFBi) induced hepatotoxicity and the resulting compensatory cell proliferation are critical for the growth of preneoplastic lesions was investigated. A commonly utilized protocol which consists of 10 doses...
Coherent states. Quantum field theory. Nonlinear theories.
In this thesis we study the properties of time-dependent, nontopological configurations and their effect on the macroscopic properties of a system described by a nonlinear field theory. These structures seem to be ubiquitous in relativistic field...
Magnetic nanoparticles are promising candidates for use in biomedical applications as remote sensors of biophysical properties, thermal therapy agents, and detectors of specific biomolecules. Many approaches have been used to model magnetic...
For a local field K, we study the affine buildings Ξ n and Δ n naturally associated to SL n ( K ) and Sp n ( K ), respectively. Since Sp n ( K ) is a subgroup of SL 2 n ( K ), we investigate properties of a natural embedding of Δ n in Ξ 2 n ....
A variety of forensic methods have been developed to identify falsified photos, each unified by the ability to estimate and detect properties of a photo that are perturbed by forgery. There exist, however, many photos in which the required...
In this thesis, we consider several problems relating to cyclic subgroups of the group [mathematical equation]. Each element of [mathematical equation] has a unique representative in one of the two intervals [mathematical equation] and...
Infrared imaging. Image reconstruction. Optical images -- Mathematical models. Breast -- Imaging. Infrared radiation in medicine.
Finite element based reconstruction algorithms for optical property profiling in biological tissues have been developed, implemented and evaluated using simulated data and laboratory measurements obtained with near infrared continuous wave (cw) and...
Cancer Control Program (National Cancer Institute) -- Evaluation. Cancer -- Treatment -- United States -- Evaluation. Cancer -- Patients -- Care -- Evaluation.
Background. Disparities in access to cancer care and cancer-related outcomes have been demonstrated in the U.S. Patterns of access to National Cancer Institute-designated Cancer Centers (NCI-CCs), the most specialized cancer care settings, have not...
Graph algorithms. Nuclear magnetic resonance spectroscopy -- Data processing. Proteins -- Structure -- Mathematical models. Proteins -- Crosslinking -- Mathematical models. Protein folding -- Mathematical models.
The study of three-dimensional protein structures produces insights into protein function at the molecular level. Graphs provide a natural representation of protein structures and associated experimental data, and enable the development of graph...
In the past few years there has been a tremendous growth in the usage of digital images. Users can now access millions of photos, a fact that poses the need of having methods that can efficiently and effectively search the visual information of...
Wireless communication systems. Computer network protocols.
We evaluate mobility predictors in wireless networks. Handoff prediction in wireless networks has long been considered as a mechanism to improve the quality of service provided to mobile wireless users. Most prior studies, however, were based on...
The problem of moving rigid bodies efficiently is of particular interest in robotics because the simplest model of a mobile robot or of a manipulated object is often a rigid body. Path planning, controller design and robot design may all benefit...
Polynomials. Finite fields (Algebra). Algebraic functions. Number theory.
The ring of univariate polynomials over a finite field shares many foundational arithmetic properties with the ring of rational integers. This similarity makes it possible for many problems in elementary number theory to be translated 'through the...
The ubiquitous complexity of common diseases is one of the biggest challenges facing the field of personalized treatments and precision medicine. This complexity can be attributed to various sources such as the genetic make-up of an individual,...
Type 4 prepilins and prepilin-like-proteins are secreted by a wide range of bacterial species and are required for a variety of functions including type 4 pilus (Tfp) formation, toxin and other enzyme secretion, gene transfer, and biofilm...
Three-dimensional imaging in medicine -- Mathematical models. ; Stereoencephalotomy.
In the past, clinicians skilled at image-guided neurosurgery have relied solely on pre-operative scans for their navigational information. Often in the course of surgery, tissue is purposely retracted/resected or inadvertently moved resulting in a...
The problem of perceived annoyance as a function of number of noise events and maximum noise level was investigated in a series of seven laboratory experiments. Four models were tested: the Equal Energy Model, the Scandinavian Model, the Variance...
This thesis reports work on a new device to detect changes in spatially nonuniform intensity distributions, and shows how this device can be applied to the particular problem of optical vibration detection. The phase of optical radiation is very...
Automatic control -- Sensitivity. Structural control (Engineering). Strains and stresses -- Computer simulation. Structural analysis (Engineering). Engineering models.
Autonomous damage detection in engineering structures is critically important as the demands placed upon those structures are increased. It has been well established that damage detection can be done through monitoring the modal frequencies of the...
Our conscious experience of memory often includes reconstuctions of the past in order to fill the gaps of forgotten events and details. The goal of this thesis is to use the tools of cognitive neuroscience to better understand the cognitive and...
Proteins -- Structure -- Data processing. Proteins -- Analysis -- Data processing. Nuclear magnetic resonance spectroscopy. Oligomers -- Analysis -- Data processing.
Symmetric homo-oligomers (protein complexes with similar subunits arranged symmetrically) play pivotal roles in complex biological processes such as ion transport and cellular regulation. Structure determination of these complexes is necessary in...