The Border Gateway Protocol (BGP) that manages inter-domain routing on the Internet lacks security. Protective measures using public key cryptography introduce complexities and costs. To support authentication and other security functionality in...
This thesis approaches the problem of locating zero-day exploits used in network attacks. The hypothesis is that the advent of high-performance virtualization presents a unique opportunity to both discover these events and increase the attacker's...
Primary care (Medicine) -- United States -- Evaluation. ; Medicine -- Specialties and specialists. ; Physicians -- Supply and demand -- United States.
Background. Strengthening the role of primary care is considered a key element in improving the outcomes and efficiency of health care delivery. Previous studies of the benefits of primary care have primarily examined the association of primary...
Primary care (Medicine) -- United States -- Evaluation.
Medicine -- Specialties and specialists.
Physicians -- Supply and demand -- United States.
Background: Strengthening the role of primary care is considered a key element in improving the outcomes and efficiency of health care delivery. Previous studies of the benefits of primary care have primarily examined the association of primary...
Black-throated blue warbler -- Habitat. Black-throated blue warbler -- Behavior. Black-throated blue warbler -- Food. Black-throated blue warbler -- Nests.
Does early and sustained experience with two languages in childhood modify how language is processed in the adult bilingual brain? Does extensive exposure to two languages influence language processing in the bilingual brain as compared to...
Many environmental toxicants found in pesticides, herbicides, and industrial solvents are believed to have deleterious effects on development by disrupting hormone-sensitive processes. Xenopus embryos were exposed to commonly encountered endocrine...
All ecological theories regarding the distribution and relative abundance of species refer to organisms'' abilities to utilize an environment and (sometimes implicitly) their ability to colonize and re-colonize habitats that change in character or...
Forest ecology -- Northeastern States. ; Forest canopy ecology -- Northeastern States. ; Forest dynamics -- Northeastern States.
In closed-canopy forests, changes in the relative abundance of tree species due to major disturbance or to its absence are thought to be governed principally by differences among component species in the performance of juveniles. However, few...
Identifying and understanding sources of individual variation in fecundity is of central importance to life history theory and population ecology. In this study, I first examined how factors on the breeding grounds in eastern Maryland affected the...
Gyrinophilus -- Ecology. ; Gyrinophilus -- Geographical distribution -- Northeastern States. ; Freshwater ecology -- Northeastern States. ; Amphibian populations -- Northeastern States.
I investigated controls on the distribution and abundance of the salamander Gyrinophilus porphyriticus (Plethodontidae) acting at multiple spatial scales: individual first-order streams, headwater drainages comprised of multiple streams, and the...
Tadpoles -- Ecology -- Atlantic States. ; Anura -- Evolution -- Atlantic States. ; Tadpoles. ; Bufonidae -- Atlantic States. ; Ranidae -- Atlantic States. ; Hylidae -- Atlantic States.
Understanding the distribution of species is a long-standing goal of ecology. Progress toward this understanding requires elucidation of how present-day patterns have been generated through history. Accomplishing this demands the study of...
Radiculitis -- Endocrine aspects. Radiculitis -- Sex factors. Radiculitis -- Pathophysiology. Pain -- Sex factors. Progesterone -- Physiological effect. Cellular signal transduction. Neuregulin-1 -- physiology.
Chronic low back pain is a debilitating and devastating disease affecting millions of people worldwide. Considerable evidence indicates that there are sex-related differences in clinical and experimental pain sensitivity in men and women. Women...
Atlantic salmon -- Growth. Atlantic salmon -- Effect of predation on -- Connecticut River Watershed. Atlantic salmon -- Mortality -- Connecticut River Watershed. Fish populations. Atlantic salmon -- Toxicology -- Connecticut River Watershed. Cottus...
Juvenile, stream-dwelling salmon are a model system for studies of density dependence. However, while salmon exhibit diverse mechanisms and patterns of density dependence, the factors that drive variation in density dependence are not clear. I used...
Urban and suburban development is a dominant factor driving ecological processes at local and regional scales and its impacts on biodiversity and ecosystem services are alarming. Pollinators, especially bees, and the ecosystem services they...
Objectives: This dissertation comprises three essays on geographic variations in healthcare, and the association between utilization and health outcomes. I first explore associations between outpatient visits and Medicare beneficiaries'...
Ultra-high molecular weight polyethylene (UHMWPE) remains the most common bearing material for total joint arthroplasty. Advances in radiation cross-linking and other post-consolidation treatments have led to a rapid differentiation of polyethylene...
Temperature has powerful effects on all scales of biological organization from biochemical reactions to ecosystem processes. Despite the well-appreciated influence and thorough understanding of the physiological and population consequences of...
Gene set testing has become a critical tool for interpreting the results of high-throughput genomic experiments. Despite the development of robust statistical methods and extensive gene set collections, however, the results from gene set testing...
The present thesis is focused on developing a better understanding of factors driving disease biology and overall risk using cancers of the bladder and breast as model systems. As no single approach was likely to unravel the complexities of these...
Fir waves are spatially and temporally repeating patterns of stand development and destruction in subalpine, balsam fir-dominated forests of the northeastern United States, perpetuated by downwind migration of strips of dying trees, "dieback...
GABA -- Receptors. Anabolic steroids -- Physiological effect. Androgens -- Physiological effect. Prosencephalon. Neurotransmitters -- Effect of drugs on. Psychoneuroendocrinology.
Anabolic androgenic steroids (AAS) are derivatives of testosterone originally designed for therapeutic applications to enhance anabolic potency (protein synthesis and muscle growth) while exerting low androgenic (masculinizing) effects. The...
The eukaryotic flagellum is a complex organelle that uses the force generated by dynein motors to cause beating motion of the flagellum. The central apparatus of eukaryotic flagella has been implicated in the regulation of dynein-driven motility....
Nutrients play fundamental roles in biological systems, affecting plant growth and quality, community structure, and species interactions. Although the effects of nutrients on primary and secondary production have been well documented, their...
Eukaryotic cells are compartmentalized into membrane-enclosed organelles. Genetic screens and reconstituted biochemical assays have revealed that intracellular protein trafficking is mediated by a conserved mechanism of vesicle budding, transport,...
Earlier work has suggested that various neurological or neuropsychiatric disorders may result in characteristic spatial patterns in brain activation, potentially allowing their detection from maps of brain activity under different conditions....
In this dissertation, I present an examination of the role of two biotic interactions in the population dynamics of Vibrio cholerae. Traits with a genetic basis such as size, physiological processes, stress tolerance, and even behavior, are key...
I investigated the effects of two contemporary disturbances to soil systems: forest clearing in the northeastern U.S. and climate-driven plant succession in the Arctic. To test the effects of clear-cutting forests on mineral soil carbon (C)...
The ubiquitous complexity of common diseases is one of the biggest challenges facing the field of personalized treatments and precision medicine. This complexity can be attributed to various sources such as the genetic make-up of an individual,...
Mutualisms may facilitate coupled population expansion or decline if changes in either partner species lead to similar changes in the other species. However, few studies have measured how both species in a mutualism respond to changes in each...