Dartmouth Digital Library Program

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Combined MRI and near-infrared spectroscopy for increased specificity of breast cancer imaging / by Michael A. Mastanduno.
A yearly breast contrast-MR scan is recommended to high-risk women because of MR's high sensitivity to breast tumors. However, breast contrast-MR yields a high number of false positives that lead to expensive and sometimes unnecessary biopsy...
Dartmouth Dissertations

Rejuvenation of cohesion during meiotic prophase is required for maintenance of chiasmata and accurate chromosome segregation / by Katherine Adalia Weng.
Accurate chromosome segregation in human oocytes requires that meiotic sister chromatid cohesion remain intact for decades and work in model organisms indicates that deterioration of meiotic cohesion over time may be a major determinant of...
Dartmouth Dissertations

Endogenous leukocyte activation by chimeric antigen receptor T cell immunotherapy / by Paul Spear.
Many protocols for adoptive T cell therapy (ACT) include preparative conditioning strategies to deplete host lymphocytes prior to T cell infusion. Total body irradiation and high-dose chemotherapy regimens not only relieve immunosuppression, but...
Dartmouth Dissertations

Utilization and health outcomes in a spatial model of the US health care system / by Laura C. Yasaitis.
Objectives: This dissertation comprises three essays on geographic variations in healthcare, and the association between utilization and health outcomes. I first explore associations between outpatient visits and Medicare beneficiaries'...
Dartmouth Dissertations

The evolution of mate recognition in Oecanthus tree crickets / by Laurel Symes.
Many organisms recognize and respond to categories: predator, prey, rival, or juvenile. Organisms recognize these ecologically-important categories by assessing diverse sensory stimuli. A primary focus of my research has been understanding how...
Dartmouth Dissertations

Intrinsic photoconductivity in molecular crystals,
Crystals -- Electric properties.; Photoconductivity.
Dartmouth Dissertations

Energy gaps and infrared spectra by electron tunneling.
Tunneling (Physics); Energy levels (Quantum mechanics).
Dartmouth Dissertations

Evaluation and engineering of Saccharomyces cerevisiae for cellulase expression and growth on insoluble cellulose.
Saccharomyces cerevisiae -- Genetics. Cellulase -- Biotechnology. Cellulose -- Biotechnology. Biomass conversion -- Technological innovations.
Dartmouth Dissertations

Quantitative study of perceptual vector analysis.
Vector analysis. Motion perception (Vision)
Dartmouth Dissertations

Examining functional variation in oncogene biology : the role of somatic mutations and germline variation on c-Myc and c-Myb / by Scott Andrew Turner.
The identification and characterization of functional genetic variation is essential for future advances in molecular diagnostics, pharmacogenomics, and personalized medicine. Recent attempts at identifying nucleotide level variation (somatic...
Dartmouth Dissertations

Microbial mediation of plant-pollinator interactions / by Robert N. Schaeffer II.
Floral nectar of many plant species is prone to colonization by microorganisms. Their presence and metabolism have the potential to modify a suite of traits important for pollinator attraction, including nectar quality and scent. However, studies...
Dartmouth Dissertations

The role of DEG/ENaC ion channel subunits in pheromone detection and mating behaviors in Drosophila melanogaster / by Vinoy Vijayan.
Gustatory pheromones regulate mating behaviors in Drosophila melanogaster and represent an important model for understanding how sensory stimuli can drive behavior. However, the genes and cells involved in pheromone detection have remained poorly...
Dartmouth Dissertations

Modflows : methods for studying and managing mesh editing workflows / by Jonathan D. Denning.
At the heart of computer games and computer generated films lies 3D content creation. A student wanting to learn how to create and edit 3D meshes can quickly find thousands of videos explaining the workflow process. These videos are a popular...
Dartmouth Dissertations

Opinion dynamics in social networks / by Qi Gu.
Opinion dynamics is a complex procedure that entails a cognitive process when it deals with how a person integrates influential opinions to form revised opinion. Early research on opinion formation and social influence can be traced back to the...
Dartmouth Dissertations

Towards the experimental verification of macroscopic phenomena in quantum electrodynamics.
Casimir effect. Zero-point field. Electric conductivity. Quantum electrodynamics.
The Casimir force arises from an alteration of boundary condition in vacuum and is often regarded as a manifestation of quantum zero point energy. Considerable progress has been made in the last decade with an impressive achievement of experimental...
Dartmouth Dissertations

Leptin DNA methylation and maternal and infant pregnancy outcomes in the Rhode Island child health study / by Corina Lesseur Perez.
In utero exposure to maternal malnutrition is associated with increase offspring susceptibility to cardiometabolic and neuropsychiatric disease. Epigenetic mechanisms mediate, at least in part, fetal adaptations to adverse in utero environments...
Dartmouth Dissertations

Cognitive and neural mechanisms of social motivation / by Katherine E. Powers.
The need for social connection is a pervasive and powerful human drive. When this fundamental need is not fulfilled, people place greater emphasis on forming social bonds and are motivated to behave in ways consistent with accomplishing these...
Dartmouth Dissertations

The role of gut commensals in regulating susceptibility to acute liver damage / by Stela Celaj.
Liver disease of different etiologies confers significant morbidity and mortality and hence it constitutes a major health concern worldwide. Stemming from a range of causes, such as viral, drug-induced, alcoholic, or autoimmune, the rate of...
Dartmouth Dissertations

Thermodynamic and spectroscopic studies of metalloprotein stability ligation and reactivity / by George P. Lisi III.
Metal ions confer structural stability and reactivity to a large number of proteins that use the amino acids histidine (His) and cysteine (Cys) to form stable metal-ligand complexes. The stability of metal-His and metal-Cys interactions and their...
Dartmouth Dissertations

Exercise and the brain : impacts on cognition neural function and mental health / by Andrea M. Robinson.
It has been well established that physical exercise has broad impacts across the lifespan, including improved cognition, brain function, and mental health. Studies investigating the mechanism underlying the cognitive enhancing effect of exercise...
Dartmouth Dissertations

Sexual selection and sexual conflict in Anolis lizards : from molecules to populations / by M. Catherine Duryea.
Sexual selection is a driver of biodiversity and creates spectacular forms of variation. However, only recently have we begun to understand how this variation operates on the postcopulatory level and how cryptic mechanisms affect male-male...
Dartmouth Dissertations

Role of NA[subscript v]1.1 in septo-hippocampal coordination of theta rhythm and spatial memory : implications for cognitive deficits in Dravet syndrome / by Alex C. Bender
In the nervous system, neuronal communication relies critically on the function of membrane ion channels. One of these is the voltage-gated sodium channel (VGSC), which is essential for the generation and propagation of action potentials in...
Dartmouth Dissertations

The role of mediator in white-opaque switching / by Anda Zhang.
The multisubunit eukaryotic Mediator complex integrates diverse positive and negative gene regulatory signals and transmits them to the core transcription machinery. It is also involved in chromatin structure related epigenetic silencing through...
Dartmouth Dissertations

Small molecule modulation of morphology and metabolism in Candida albicans / by Allia Kaye Smith
Candida albicans is a fungal species that naturally exists as a commensal member of the human microbiota, but can assume a pathogenic lifestyle and subsequently induce life-threatening systemic infections. The ability of the fungus to grow in...
Dartmouth Dissertations

Cataclysmic variables and white dwarf-m dwarf binaries from the superblink proper motion survey / by Julie Nicole Skinner.
Cataclysmic variable stars (CVs) are close, interacting binary systems comprised of a white dwarf and a companion star, which is typically a late-type dwarf star. Their progenitor systems are post common envelope binaries (PCEBs) with a white dwarf...
Dartmouth Dissertations

Novel dimensions in a fluid genome : an integrative risk analysis for cancers of the bladder and breast / by Asaf Wyszynski.
The present thesis is focused on developing a better understanding of factors driving disease biology and overall risk using cancers of the bladder and breast as model systems. As no single approach was likely to unravel the complexities of these...
Dartmouth Dissertations

Importance of nest predation to avian population regulation and community structure in a northern hardwoods fores
Bird populations -- New Hampshire; Predation (Biology); Birds -- Nests; Black-throated blue warbler; Chipmunks; Tamiasciurus hudsonicus
Dartmouth Dissertations

Habitat selection by breeding black-throated blue warblers: different patterns at two spatial scales and the use of habitat for foraging and nesting.
Black-throated blue warbler -- Habitat. Black-throated blue warbler -- Behavior. Black-throated blue warbler -- Food. Black-throated blue warbler -- Nests.
Dartmouth Dissertations

Self/other perception of the intensity of facial expressiveness : do we know what we show?
Facial expression.; Emotions. ; Self-perception.
Dartmouth Dissertations

Nocturnality and defense in the rat: selective association of light and aversive stimulation.
Rats -- Behavior. Nocturnal animals. Defensiveness (Psychology). Aversive stimuli.
Dartmouth Dissertations

Dendritic cell Fcγ receptor expression and function
Fc receptors. Dendritic cells. Immune recognition.
Three types of Fc receptors for IgG, FcyRI (CD64), FcyRII (CD32), and FcyRIII (CD 16) are expressed differentially on blood leukocytes. In particular, CD64 and CD32 are constitutively expressed on mononuclear phagocytes of the human myeloid system....
Dartmouth Dissertations

Implementation, characterization, and applications of a scanning Kelvin probe force microscope.
Scanning force microscopy. Scanning electron microscopes -- Design and construction. Semiconductors -- Analysis.
Dartmouth Dissertations

Electrical impedance imaging for temperature field estimation during hyperthermia treatment of cancer.
Electrical impedance tomography. Newton-Raphson method. Cancer -- Thermotherapy -- Technique.
Dartmouth Dissertations

Investigation of dynamic sea ice processes in the Weddell Sea during 1992.
Sea ice -- Antarctica -- Weddell Sea.
Through a series of case studies, signal processing and statistical tools, analyses of dynamic sea ice processes of drift, deformation, and ice pack expansion and decay are investigated for the Weddell Sea region during 1992. Cavitating fluid (CAV)...
Dartmouth Dissertations

The effects of context and familiarity on person perception: examining the neural substrates of facial attractiveness.
Face perception -- Physiological aspects. Face perception -- Social aspects. Sex differences (Psychology). Neuropsychology.
The general objective of the current thesis was to investigate the neural substrates underlying the perception of opposite-sex faces. Building on what is already known about the distributed network of brain areas supporting various dimensions of...
Dartmouth Dissertations

A Cerenkov-Raman maser.
Masers. Cherenkov radiation.
Dartmouth Dissertations

The adaptation of a potential function controller for control of a dynamic multi-robot system.
Robots -- Control systems -- Design and construction. Mobile robots. Robots -- Dynamics.
This thesis examines the issues of vehicle and information dynamics in the control of a multi-robot system using a radial-basis potential function controller. Distributed control of multi-robot systems requires each robot to communicate state...
Dartmouth Dissertations

Optimizing winding designs for high-frequency magnetic components.
Electric generators -- Windings. Electric inductors -- Design and construction -- Mathematical models. Electric current converters -- Design and construction -- Mathematical models. Energy dissipation -- Mathematical models.
Magnetic components for high-frequency power conversion applications can have significant losses that compromise the performance of the converter. In particular, winding losses can be large due to high-frequency effects that are difficult to model...
Dartmouth Dissertations

Effects of chronic anabolic androgenic steroid exposure on GABAergic neurotransmission and neuronal activity in the mamalian forebrain.
GABA -- Receptors. Anabolic steroids -- Physiological effect. Androgens -- Physiological effect. Prosencephalon. Neurotransmitters -- Effect of drugs on. Psychoneuroendocrinology.
Anabolic androgenic steroids (AAS) are derivatives of testosterone originally designed for therapeutic applications to enhance anabolic potency (protein synthesis and muscle growth) while exerting low androgenic (masculinizing) effects. The...
Dartmouth Dissertations

Cerenkov radiation in dielectric-loaded waveguides.
Cherenkov radiation.
Dartmouth Dissertations

Isolation and functional characterization of yeast vacuole snare complexes.
Membrane proteins -- Physiological transport. ; Plant proteins -- Physiological transport. ; Biological transport -- Regulation. ; Plant vacuoles. Saccharomyces cerevisiae -- Physiology.
Eukaryotic cells are compartmentalized into membrane-enclosed organelles. Genetic screens and reconstituted biochemical assays have revealed that intracellular protein trafficking is mediated by a conserved mechanism of vesicle budding, transport,...
Dartmouth Dissertations

Anticipated emotion in health decision making : an extension of the prototype-willingness model
Health behavior -- Decision making. ; Emotions.
Dartmouth Dissertations

Allosteric modulation of GABAa receptors by anabolic-androgenic steroids.
GABA -- Receptors. Allosteric regulation. ; Anabolic steroids -- Physiological effect. ; Androgens -- Physiological effect. ; Receptors
Anabolic-androgenic steroids (AAS) are synthetic derivatives of the gonadal hormone, testosterone. Despite their many untoward side effects, AAS are wildly abused for their ergogenic properties. AAS have numerous effects on many organ systems,...
Dartmouth Dissertations

Mapping the junction of action perception and production.
Perceptual-motor learning -- Physiological aspects. ; Language acquisition -- Physiological aspects. ; Motor ability -- Physiological aspects. ; Knots and splices.
The studies presented in this dissertation explore several points of intersection between action perception and production within the human brain. One's ability to use perceptual information about another individual's actions to guide and inform...
Dartmouth Dissertations

Interval tolerance orders and dimension.
Partially ordered sets. ; Graph theory.
Dartmouth Dissertations

Aging minds and twisting attitudes: effects of age-related decline in executive function on older adults' attitudes toward stigmatized individuals.
Stigma (Social psychology). Aging -- Psychological aspects. Cognition -- Age factors. Older people -- Attitudes.
Extensive research on aging has demonstrated that normal aging debilitates executive function, a system that is critical for regulating stereotypes. However, there is a paucity of research on whether age-related declines to executive function...
Dartmouth Dissertations

Diaphragmatic electromyogram and airflow responses to imperceptible mechanical loads in conscious humans
Respiration -- Regulation. ; Pressure breathing.
Dartmouth Dissertations

Prime polynomials over finite fields.
Polynomials. Finite fields (Algebra). Algebraic functions. Number theory.
The ring of univariate polynomials over a finite field shares many foundational arithmetic properties with the ring of rational integers. This similarity makes it possible for many problems in elementary number theory to be translated 'through the...
Dartmouth Dissertations

The ecology of Vibrio cholerae: intra- and interspecific interactions.
Vibrio cholerae -- Ecology. Vibrio cholerae -- Growth. Cyanobacteria -- Ecology.
In this dissertation, I present an examination of the role of two biotic interactions in the population dynamics of Vibrio cholerae. Traits with a genetic basis such as size, physiological processes, stress tolerance, and even behavior, are key...
Dartmouth Dissertations

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