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- A knowledge-based environment for the automated design of analog electronic circuits.
- Electronic analog computers -- Circuits -- Design and construction -- Computer programs. ; SLADE (Computer program).
- Dartmouth Dissertations
- Mechanisms for chromium-induced signaling changes in pulmonary epithelial cells.
- Chromium -- Pathophysiology. ; Lungs -- Pathophysiology. ; Epithelial cells. ; Cellular signal transduction. ; Transcription factors -- Pathophysiology. ; Protein kinases -- Pathophysiology. ; src-Family Kinases. ; Mitogen-Activated Protein Kinases.
- Both human epidemiological and animal studies have associated inhalation of chromium(VI) (Cr(VI)) with increased incidence of pulmonary disease. This thesis examined the hypotheses that Cr(VI) activates cell signaling through kinase cascades and...
- Dartmouth Dissertations
- Experiment planning for protein structure elucidation and site-directed protein recombination.
- Proteins -- Structure -- Computer simulation -- Experiments. ; Amino acid sequence -- Data processing -- Experiments. Protein engineering -- Experiments. ; Recombinant proteins -- Mathematical models.
- In order to most effectively investigate protein structure and improve protein function, it is necessary to carefully plan appropriate experiments. The combinatorial number of possible experiment plans demands effective criteria and efficient...
- Dartmouth Dissertations
- The molecular basis of chromium carcinogenesis.
- Chromium. ; Carcinogens.
- Dartmouth Dissertations
- Improvements in conservative parallel simulation of large-scale models.
- Large scale systems -- Mathematical models. Digital computer simulation. Parallel processing (Electronic computers). Computer algorithms.
- Modeling real-world large-scale systems is inherently challenging due to their size and complexity. Detailed simulation of large-scale models requires tremendous amounts of computing power and memory space. Parallel discrete-event simulation...
- Dartmouth Dissertations
- Spectroscopic reconstructed near infrared tomographic imaging for breast cancer diagnosis.
- Breast -- Cancer -- Tomography. ; Breast -- Cancer -- Imaging. ; Breast -- Cancer -- Diagnosis. ; Near infrared reflectance spectroscopy. ; Image processing -- Digital techniques.
- Near-infrared (NIR) light has the potential to be used as a non-invasive means of diagnostic imaging within the human breast. Due to the diffusive nature of light in tissue, computational model-based methods are required for functional imaging...
- Dartmouth Dissertations
- Broadband near-infrared tomography for breast cancer imaging.
- Breast -- Cancer -- Tomography. Near infrared spectroscopy. Breast -- Cancer -- Imaging. Breast -- Cancer -- Diagnosis.
- Near-infrared (NIR) light provides potential for a new approach to non-invasive detection, diagnosis and clinical management of breast cancer. Using NIR spectroscopic imaging techniques, the physiological information about breast tissue composition...
- Dartmouth Dissertations
- Electrical impedance imaging for temperature field estimation during hyperthermia treatment of cancer.
- Electrical impedance tomography. Newton-Raphson method. Cancer -- Thermotherapy -- Technique.
- Dartmouth Dissertations
- A spectroscopic investigation of chromium-thiolate complexes.
- Chromium. Glutathione.
- Dartmouth Dissertations
- Characterization of the interaction of the chemotherapeutic drug mitomycin C with DNA in vitro and in vivo and effects on specific DNA-protein interactions.
- Mitomycin C -- Mechanism of action. ; DNA -- Effect of mitomycin C on. ; Genetic expression -- Effect of mitomycin C on. ; DNA-protein interactions -- Effect of mitomycin C on.
- Mitomycin C (MMC) is a chemotherapeutic drug that reacts with the N$\sp2$ of guanine to form monoadducts, interstrand and intrastrand crosslinks. These lesions, especially the interstrand crosslink, are believed to be responsible for the potent...
- Dartmouth Dissertations
- Naming and sharing resources across administrative boundaries.
- Electronic data processing -- Distributed processing. ; Computer network architectures. ; Programming languages (Electronic computers) -- Semantics. ; Database management.
- I tackle the problem of naming and sharing resources across administrative boundaries. Conventional systems manifest the hierarchy of typical administrative structure in the structure of their own mechanism. While natural for communication that...
- Dartmouth Dissertations
- Proper actions of groupoids on C*-algebras.
- Groupoids. C*-algebras. Crossed products. Brauer groups.
- This thesis contains some results concerning groupoid dynamical systems and crossed products. We introduce the notion of a proper groupoid dynamical system and of its generalized fixed point algebra. We show that our notion of proper groupoid...
- Dartmouth Dissertations
- Reactive intermediates in chromium carcinogenesis.
- Chromium -- Toxicology. Carcinogenesis.
- Dartmouth Dissertations
- Design and control of high-density DC-DC converters for cell balancing and low-voltage power delivery applications / by Christopher Schaef
- In a variety of applications spanning mobile devices, performance computing, and even renewable energy and automotive, power management and power delivery are an increasing bottleneck in reducing size and cost, improving reliability, and even...
- Dartmouth Dissertations
- Ultrastructure and histochemistry of the cellular stomach and gastric gland of female Asplanchna sieboldi and of the rudimentary gut of male Asplanchna sieboldi.
- Rotifera.
- Dartmouth Dissertations
- An NMR study of relaxation in CHC1F2.
- Nuclear magnetic resonance.
- Dartmouth Dissertations
- Transformation monoids of algebraic number rings.
- Monoids. ; Transformations (Mathematics). ; Rings (Algebra). ; Galois theory.
- Dartmouth Dissertations
- Cellular and molecular effects of chromium on the activity and expression of fibrinolytic proteins in epithelial cells.
- Chromium -- Therapeutic use. ; Fibrinolysis. ; Epithelial cells. ; Pulmonary fibrosis.
- Transition metals play critical roles in biological systems as essential components of metalloproteins and metalloenzymes, as diagnostic probes and pharmaceuticals, and in some instances, as sources of toxicity. Cellular concentrations vary...
- Dartmouth Dissertations
- Investigations on optimizing the energy transmission of ultrafast optical pulses in pure water.
- Laser pulses, Ultrashort. Electromagnetic waves -- Transmission.
- Many of today's communication and imaging technologies share the common challenge of signal deterioration due to water's large absorption coefficient. As an example, it is water molecules that contaminate the fused silica of optical fibers and...
- Dartmouth Dissertations
- The scaling of forced reconnection in two and three dimensions.
- Magnetic reconnection -- Mathematical models. Plasma (Ionized gases). Magnetohydrodynamics -- Mathematical models. Scaling laws (Statistical physics). Forcing (Model theory).
- This thesis presents two-fluid simulations of forced magnetic reconnection with finite electron inertia in two and three dimensional periodic systems. Reconnection in the system is driven by a spatially localized forcing function, added to the ion...
- Dartmouth Dissertations
- Implementation, characterization, and applications of a scanning Kelvin probe force microscope.
- Scanning force microscopy. Scanning electron microscopes -- Design and construction. Semiconductors -- Analysis.
- Dartmouth Dissertations
- Microwave imaging for 2-D electrical property distribution profiling.
- Image reconstruction. Microwave imaging. Microwave imaging -- Instruments -- Design and construction. Microwave imaging in medicine.
- Dartmouth Dissertations
- Mesh-Mon: a monitoring and management system for wireless mesh networks.
- Wireless communication systems. Computer networks. Routers (Computer networks).
- A mesh network is a network of wireless routers that employ multi-hop routing and can be used to provide network access for mobile clients. Mobile mesh networks can be deployed rapidly to provide an alternate communication infrastructure for...
- Dartmouth Dissertations
- The optical spectrum of SCO X-1
- Stars -- Spectra
- Dartmouth Dissertations
- Design of a magnetic field compatible, high-performance optical breast imaging system for MRI-guided optical spectroscopy / by Fadi El-Ghussein
- Multimodality imaging is becoming the standard of care for research and clinical studies. Such an approach is able to provide complementary information which can detect and characterize tumors. Advancing instrumentation for diffuse near-infrared...
- Dartmouth Dissertations
- Geology and paleomagnetics of three old red sandstone basins: Spitsbergen, Norway and Scotland.
- Paleomagnetism -- Norway. ; Paleomagnetism -- Norway -- Spitsbergen Island. ; Paleomagnetism -- Scotland. ; Sandstone -- Norway. ; Sandstone -- Norway -- Spitsbergen Island. ; Sandstone -- Scotland.
- Dartmouth Dissertations
- Satake parameters of Siegel modular forms.
- Siegel domains. Modular groups. Hecke algebras. Forms
- In the 1960s Satake proved the existence of an isomorphism between the local Hecke algebra and the ring of polynomials invariant under the action of the signed permutation group W n (the Weyl group associated to Sp n over a local field)....
- Dartmouth Dissertations
- Part I. Tetraaminoethylenes and diaminocarbenes; Part II. The attempted synthesis of perfluorobicyclo[1.1.0]butane and perfluorobicyclo[2.1.0]pentane.
- Carbenes (Methylene compounds) -- Synthesis. ; Organofluorine compounds -- Synthesis.
- Dartmouth Dissertations
- Some results on Souslin trees.
- Trees (Graph theory). ; Set theory.
- Dartmouth Dissertations
- Molecular, cellular, and physiological characterization of the insulin receptor substrate 4.
- Protein-tyrosine kinase. ; Insulin -- Receptors.
- Upon activation by binding of insulin, the insulin receptor tyrosine kinase phosphorylates a group of proteins known as the insulin receptor substrates (IRS's). The tyrosine phosphorylated IRS's then act as docking/effector molecules for SH2...
- Dartmouth Dissertations
- Tangles, theta graphs and solid torus pairs.
- Torus (Geometry). ; Functions Theta.
- Dartmouth Dissertations
- Finite element simulation of two-dimensional incompressible magnetohydrodynamic flows.
- Magnetohydrodynamics -- Simulation methods. ; Finite element method. ; Galerkin methods.
- Dartmouth Dissertations
- Damage identification using sensitivity enhancing control with an identified model.
- Automatic control -- Sensitivity. Structural control (Engineering). Strains and stresses -- Computer simulation. Structural analysis (Engineering). Engineering models.
- Autonomous damage detection in engineering structures is critically important as the demands placed upon those structures are increased. It has been well established that damage detection can be done through monitoring the modal frequencies of the...
- Dartmouth Dissertations
- Appearance-design interfaces and tools for computer cinematography: evaluation and application.
- Digital cinematography. ; Cinematography -- Lighting -- Data processing -- Evaluation. ; Cinematography -- Special effects -- Data processing -- Evaluation. ; User interfaces (Computer systems) -- Evaluation.
- We define appearance design as the creation and editing of scene content such as lighting and surface materials in computer graphics. The appearance design process takes a significant amount of time relative to other production tasks and poses...
- Dartmouth Dissertations
- Nuclear spin interactions in dilute solid mixtures of 3He and 4He.
- Electromagnetic interactions. ; Nuclear reactions. ; Nuclear spin.
- Dartmouth Dissertations
- Multiplicatively weighted crystal growth Voronoi diagrams.
- Voronoi polygons. ; Crystal growth.
- Dartmouth Dissertations
- Non-resonant photon absorption by reactive chemical systems.
- Lasers in chemistry. ; Zinc. ; Oxidation-reduction reaction.
- Dartmouth Dissertations
- Digital video forensics.
- Digital video -- Analysis. Forensic sciences. Image processing -- Digital techniques.
- We present new forensic tools that are capable of detecting traces of tampering in digital video without the use of watermarks or specialized hardware. These tools operate under the assumption that video contain naturally occurring properties which...
- Dartmouth Dissertations
- The synthetic oleanane triterpenoids and the histone deacetylase inhibitor vorinostat cooperate to delay tumor development in a transgenic model of estrogen receptor-negative breast cancer / by Kim M. Tran.
- Electromagnetic fields -- Mathematical models.;""Molecular spectroscopy."";""Nucleotide sequence."";""Macromolecules -- Analysis."";""Electromagnetic induction."";""Unexploded ordnance -- Identification.""
- Dartmouth Dissertations
- Estradiol regulation of innate immune protection in the human female reproductive tract / by Mickey Vinay Patel.
- Estradiol is a key regulator of immune protection in the female reproductive tract (FRT). Its concentration varies during the menstrual cycle, leading to changes in innate immune protection. In this thesis, I demonstrate the multiple levels at...
- Dartmouth Dissertations
- Brain repair after trauma : birth and migration of immature neurons after focal traumatic brain injury in piglets and human children / by Sabrina Rose Taylor.
- Traumatic brain injury (TBI) is the leading cause of acquired disability in children, yet innate repair mechanisms are incompletely understood. A possible innate mechanism to repair injury after insult is neurogenesis - the birth, migration,...
- Dartmouth Dissertations
- Chemico-physical and pharmacologic factors that influence delivery of IONPs to tumors in rodent breast cancer models / by Jennifer Tate.
- Nanoparticles have made significant advances in recent years in the realm of cancer therapy. These nanoparticles typically range in size from 10-250nm in diameter, allowing for differential systemic-based biodistribution. The enhanced permeability...
- Dartmouth Dissertations
- Intrinsic photoconductivity in molecular crystals,
- Crystals -- Electric properties.; Photoconductivity.
- Dartmouth Dissertations
- Studies of equilibrium and dynamic properties of polymers.
- Polymers. Chemical equilibrium.
- Dartmouth Dissertations
- Biochemistry of dioxygenated triterpenoids and steroids.
- Cholesterol. Squalene. Steroids.
- Dartmouth Dissertations
- Examining functional variation in oncogene biology : the role of somatic mutations and germline variation on c-Myc and c-Myb / by Scott Andrew Turner.
- The identification and characterization of functional genetic variation is essential for future advances in molecular diagnostics, pharmacogenomics, and personalized medicine. Recent attempts at identifying nucleotide level variation (somatic...
- Dartmouth Dissertations
- Determining anthropogenic and natural controls on the global mercury cycle using lake sediment and ice cores ; by Samuel Adams Beal Jr.
- While anthropogenic emissions of the toxic element mercury (Hg) to the atmosphere are currently rising, major uncertainties remain in determining the relative impacts of anthropogenic activity and natural processes on the global Hg cycle. In this...
- Dartmouth Dissertations
- Microbial mediation of plant-pollinator interactions / by Robert N. Schaeffer II.
- Floral nectar of many plant species is prone to colonization by microorganisms. Their presence and metabolism have the potential to modify a suite of traits important for pollinator attraction, including nectar quality and scent. However, studies...
- Dartmouth Dissertations
- SirT1 regulates vascular smooth muscle cell plasticity : implications for age-related cardiovascular disease / by Anne Marie Thompson.
- Loss of vascular smooth muscle cell function is a hallmark of vascular disease. Vascular smooth muscle cells become increasingly resistant to phenotypic modulation, apoptotic and senescent. Sirtuin 1 (SirT1) is a deactylase that regulates...
- Dartmouth Dissertations
- Analytical and computational approaches for quantitative phosphoproteomics / by Jason M. Gilmore.
- Protein phosphorylation is an important regulatory mechanism for the control of countless processes in living systems. The delicate management of phosphate attachment to, and removal from, serine, threonine and tyrosine residues in proteins...
- Dartmouth Dissertations

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