Dartmouth Digital Library Program

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Combined MRI and near-infrared spectroscopy for increased specificity of breast cancer imaging / by Michael A. Mastanduno.
A yearly breast contrast-MR scan is recommended to high-risk women because of MR's high sensitivity to breast tumors. However, breast contrast-MR yields a high number of false positives that lead to expensive and sometimes unnecessary biopsy...
Dartmouth Dissertations

Utilization and health outcomes in a spatial model of the US health care system / by Laura C. Yasaitis.
Objectives: This dissertation comprises three essays on geographic variations in healthcare, and the association between utilization and health outcomes. I first explore associations between outpatient visits and Medicare beneficiaries'...
Dartmouth Dissertations

Security-policy analysis with eXtended unix tools / by Gabriel A. Weaver.
During our fieldwork with real-world organizations---including those in Public Key Infrastructure (PKI), network configuration management, and the electrical power grid---we repeatedly noticed that security policies and related security artifacts...
Dartmouth Dissertations

Analysis of zooplankton dynamics: case studies of temporal succession controlled by the predator, Asplancha, and of diel cycles in Keratella.
Freshwater zooplankton. Predation (Biology).
Dartmouth Dissertations

C.O.A.L.1: a dynamic model for the analysis of United States energy policy.
Energy policy -- United States -- Mathematical models.
Dartmouth Dissertations

The synthesis and chemistry of novel cyclic perfluoromethyl-substituted molecules.
Fluorine compounds.
Dartmouth Dissertations

Forest structure and atmospheric interactions : predictive models for subalpine balsam fir forest
Forest hydrology -- Mathematical models; Forest Meteorology -- Mathematical models; Balsam fir
Dartmouth Dissertations

Understanding PDZ affinity and selectivity: all residues considered / by Jeanine F. Amacher.
PDZ protein-protein interaction domains recognize short linear motif (SLiM) sequences typically at the extreme C-terminus of a target protein. These domains often act as scaffolds, connecting target proteins to additional interaction and catalytic...
Dartmouth Dissertations

Combined digital breast tomosynthesis and near-infrared spectral tomography for breast lesion characterization / by Kelly E. Michaelsen.
Annual screening mammograms are recommended for all women above 40 years of age for early detection of breast cancer, and are known to improve cancer mortality rates. However, mammography is hampered by low sensitivity and a high rate of false...
Dartmouth Dissertations

Temperature effects on food web interactions : from lakes to landscapes / by Samuel Butler Fey.
Temperature has powerful effects on all scales of biological organization from biochemical reactions to ecosystem processes. Despite the well-appreciated influence and thorough understanding of the physiological and population consequences of...
Dartmouth Dissertations

Memory consolidation in temporal lobe epilepsy / by Ali Seçkin Titiz.
Epilepsy is associated with cognitive impairments which often manifest as a higher prevalence of memory impairments. Memory impairments in patients with epilepsy may persist even with sufficient control of seizures, suggesting other factors may...
Dartmouth Dissertations

Exercise and the brain : impacts on cognition neural function and mental health / by Andrea M. Robinson.
It has been well established that physical exercise has broad impacts across the lifespan, including improved cognition, brain function, and mental health. Studies investigating the mechanism underlying the cognitive enhancing effect of exercise...
Dartmouth Dissertations

Role of NA[subscript v]1.1 in septo-hippocampal coordination of theta rhythm and spatial memory : implications for cognitive deficits in Dravet syndrome / by Alex C. Bender
In the nervous system, neuronal communication relies critically on the function of membrane ion channels. One of these is the voltage-gated sodium channel (VGSC), which is essential for the generation and propagation of action potentials in...
Dartmouth Dissertations

The role of mediator in white-opaque switching / by Anda Zhang.
The multisubunit eukaryotic Mediator complex integrates diverse positive and negative gene regulatory signals and transmits them to the core transcription machinery. It is also involved in chromatin structure related epigenetic silencing through...
Dartmouth Dissertations

Novel dimensions in a fluid genome : an integrative risk analysis for cancers of the bladder and breast / by Asaf Wyszynski.
The present thesis is focused on developing a better understanding of factors driving disease biology and overall risk using cancers of the bladder and breast as model systems. As no single approach was likely to unravel the complexities of these...
Dartmouth Dissertations

The bedrock geology of the Gilmanton 15-minute Quadrangle, New Hampshire.
Geology -- New Hampshire -- Gilmanton Quadrangle.
Dartmouth Dissertations

Habitat selection in the American redstart (Setophaga ruticilla): the importance of early successional habitat and the role of landscape change in population declines.
Wood warblers -- Habitat. Wood warblers -- Effect of habitat modification on. Forest ecology -- New Hampshire. Animal populations -- Mathematical models.
Dartmouth Dissertations

Characterization and rescue of a Drosophila model of prion disease; and The role of carcinine in signaling at the Drosophila photoreceptor synapse.
Drosophila melanogaster -- Genetic aspects. Prion diseases. Neurotransmitters. Photoreceptors.
Drosophila melanogaster is a model organism often used when studying the complex processes of neuronal signaling and neurodegeneration. The short life cycle, malleable genetics, amenability to in vivo electrophysiological assays and sensitivity to...
Dartmouth Dissertations

Conformationally restricted bis(9-aminoacridine)s : a chemical and biological study
Acridine.
A series of conformationally restricted bis(9-amino-acridine) derivatives were designed, synthesized, and then evaluated for their chemical and biological behavior. The novel compounds were prepared by treating selected diamines with a...
Dartmouth Dissertations

Nd, Sr and O isotopic study of midcrustal granitoid petrogenesis within the Acadian central Maine terrane.
Petrology -- Maine. Granite -- Maine. Isotope geology -- Maine.
Dartmouth Dissertations

The effect of suspended sediments on planktonic rotifers and cladocerans.
Freshwater zooplankton -- Effect of sediments on. Rotifera. Cladocera.
Dartmouth Dissertations

An electron paramagnetic resonance spectroscopic investigation of group 6 (Cr, Mo and W) transition metal complexes.
Transition metal complexes. Electron paramagnetic resonance spectroscopy.
Dartmouth Dissertations

The effects of food resources and conspecifics on the foraging, survivorship, and reproduction of the omnivorous copepod Epischura lacustris
Epischura; Epischura -- Food
Dartmouth Dissertations

Through-space hydrogen-fluorine and carbon-fluorine nuclear spin-spin coupling: an experimental study.
Nuclear magnetic resonance. Fluorine -- Spectra. Hydrogen -- Spectra.
Dartmouth Dissertations

Fluorinated ligands in organometallic chemistry.
Fluorocarbons. Ligands.
Dartmouth Dissertations

Age-specific predation and predation risk of Chaoborus punctipennis.
Chaoborus. Predation (Biology). Freshwater ecology.
Dartmouth Dissertations

The bedrock geology of the Holderness quadrangle, New Hampshire.
Geology -- New Hampshire -- Holderness Quadrangle.
Dartmouth Dissertations

Activation of vascular endothelial cells in response to mineral fibers.
Asbestosis -- Pathophysiology. Asbestosis -- Molecular aspects. Pulmonary endothelium -- Genetic aspects. Endothelium -- Effect of asbestos on. Fibers -- Toxicology.
Dartmouth Dissertations

Causes of tree mortality in wave-regenerated balsam fir forests
Balsam fir. Trees -- Physiology.
Fir waves are spatially and temporally repeating patterns of stand development and destruction in subalpine, balsam fir-dominated forests of the northeastern United States, perpetuated by downwind migration of strips of dying trees, "dieback...
Dartmouth Dissertations

The chemistry of clay minerals associated with evaporites in New York and Utah.
Clay minerals -- Composition. Chlorites. Evaporites -- New York (State). Evaporites -- Utah.
Dartmouth Dissertations

The flight behavior and dispersal ecology of the red milkweed beetle, Tetraopes tetraopthalmus
Red milkweed beetle. Insects -- Flight. Insects -- Dispersal.
Most detailed studies of insect flight and dispersal have used long flying species as subjects. Little is known of the flight ecology of comparatively short flying species. This thesis reports the findings of a 4 year study of the flight behavior...
Dartmouth Dissertations

Apoptosis as a mechanism of cell death by anticancer agents.
Apoptosis. Antineoplastic agents.
Dartmouth Dissertations

Solution chemistry of a New Hampshire subalpine ecosystem.
Forest ecology -- New Hampshire. Solution (Chemistry).
Dartmouth Dissertations

Centralized and distributed algorithms for network scheduling.
Computer algorithms. Computer networks -- Workload. Production scheduling.
Dartmouth Dissertations

Detection of hydrocarbons and hydrocarbon microseepage in the Bighorn Basin, Wyoming using isotopic, biogeochemical, and spectral reflectance techniques.
Hydrocarbons -- Secretion. Petroleum -- Geology -- Bighorn Basin (Mont. and Wyo.). Natural gas -- Geology -- Bighorn Basin (Mont. and Wyo.). Isotope geology -- Bighorn Basin (Mont. and Wyo.). Sagebrush -- Bighorn Basin (Mont. and Wyo.) -- Analysis....
Dartmouth Dissertations

Fish foraging and learning in complex environments.
Sunfishes -- Food. Sunfishes -- Effect of habitat modification on
Dartmouth Dissertations

An experimental study of the propagation and dispersion of internal atmospheric gravity waves.
Gravity waves. Ionosphere.
Dartmouth Dissertations

Stratigraphy, structure, and petrology of the Peterborough 15-minute quadrangle, New Hampshire; and Part II. Graphite textural and isotopic variations in plutonic rocks, south-central New Hampshire.
Geology -- New Hampshire -- Peterborough Quadrangle. Geology Stratigraphic. Geology.
Dartmouth Dissertations

From target discovery to high-throughput screens--selective CAL PDZ inhibitors as candidate CF therapeutics
Peptides -- Therapeutic use. ; Chloride channels -- Pathophysiology. ; Ligands (Biochemistry) ; Protein-protein interactions. ; Cystic fibrosis -- Molecular aspects. ; High throughput screening (Drug development) ; PDZ Domains. ; Cystic Fibrosis...
PDZ domains are protein:protein interaction domains that serve as molecular scaffolds, especially in the case of specialized cellular environments like polarized airway epithelial cells of the human lung. Historically the domains have been thought...
Dartmouth Dissertations

The role of decision strategies in the development of visual information processing
Visual perception. ; Child psychology.
Dartmouth Dissertations

An EPR spectroscopic investigation of paramagnetic organometallic complexes.
Organometallic compounds. ; Paramagnetism. ; Electron paramagnetic resonance spectroscopy.
Dartmouth Dissertations

The population dynamics, bioenergetics, and nutrient cycling of three species of mice in the Hubbard Brook Experimental Forest, New Hampshire, U.S.A
Mice; Forest ecology -- New Hampshire. ; Animal ecology -- New Hampshire
Dartmouth Dissertations

The use and transfer of learning strategies in the classroom.
Learning, Psychology of. ; Cognitive styles.
Dartmouth Dissertations

Characterization of the interaction of the chemotherapeutic drug mitomycin C with DNA in vitro and in vivo and effects on specific DNA-protein interactions.
Mitomycin C -- Mechanism of action. ; DNA -- Effect of mitomycin C on. ; Genetic expression -- Effect of mitomycin C on. ; DNA-protein interactions -- Effect of mitomycin C on.
Mitomycin C (MMC) is a chemotherapeutic drug that reacts with the N$\sp2$ of guanine to form monoadducts, interstrand and intrastrand crosslinks. These lesions, especially the interstrand crosslink, are believed to be responsible for the potent...
Dartmouth Dissertations

Children's interpretations of observed noncontingent reward: effects of sharing behavior.
Child psychology. ; Sharing.
Dartmouth Dissertations

Structural and compositional aspects of low-grade metamorphic chlorite.
Chlorites. Metamorphism (Geology). ; Clay -- Analysis -- Maine. ; Clay -- Analysis -- Pennsylvania.
Dartmouth Dissertations

Demographic consequences of seasonal variation in environmental stress.
Freshwater zooplankton -- Effect of temperature on. ; Freshwater zooplankton -- Food. ; Freshwater zooplankton -- Reproduction.
Dartmouth Dissertations

Soil biogeochemistry in temperate and arctic ecosystems : human disturbances to a critical carbon pool / by Chelsea L. Petrenko
I investigated the effects of two contemporary disturbances to soil systems: forest clearing in the northeastern U.S. and climate-driven plant succession in the Arctic. To test the effects of clear-cutting forests on mineral soil carbon (C)...
Dartmouth Dissertations

Understanding the role of Toxoplasma gondii secreted rhoptry (ROP) and dense granule (GRA) effector proteins in host-parasite biology using reverse genetics / by Leah M. Rommereim
Toxoplasma gondii is an obligate intracellular pathogen that is able to survive in a range of hosts due to its repertoire of secreted effector proteins. Utilizing the type I and type II Δku80 strains we engineered a collection of targeted knockout...
Dartmouth Dissertations

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