Dartmouth Digital Library Program

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A computational dissection in the evolution of cell growth.
Genetic regulation. Cells -- Growth -- Regulation. Ribosomes. DNA -- Synthesis. Evolutionary genetics.
Gene regulation is a principle tool that all organisms utilize to control development, growth, and responses to environmental conditions. Understanding how organisms orchestrate the spatiotemporal regulation of gene expression remains a fundamental...
Dartmouth Dissertations

The role of the Drosophila SK channel in sensory processing and behavior / by Ahmad Nawwaf Abou Tayoun.
Partially ordered sets. ; Forcing (Model theory). ; Set theory.
Dartmouth Dissertations

Targeting of the erythroid transcription factor, GATA-1, to specific locations within the human genome.
Globin genes -- Expression. ; Transcription factors. ; Genetic transcription -- Regulation.
Dartmouth Dissertations

Measuring quality of life in economic evaluations of treatment for severe mental illness.
Quality of life -- Evaluation. ; Health status indicators. ; Psychiatric rating scales. ; Mental illness -- Treatment -- Evaluation. ; Mental illness -- Treatment -- Economic aspects. ; Mental illness -- Treatment -- Social aspects.
Background. It is not clear whether a generic quality-of-life instrument can appropriately represent severe mental illness in an economic evaluation. This problem is particularly salient for resource-allocation decisions where policymakers compare...
Dartmouth Dissertations

Fault modeling and design of dynamic logic.
Logic programming. ; Electronic digital computers -- Circuits -- Testing -- Mathematical models. ; Fault-tolerant computing.
Today''s fastest microprocessors, logic chips, and even memory chips employ dynamic logic as the key part to achieving advanced performance. Dynamic logic only retains the correct data state briefly and is far less robust than previous technologies...
Dartmouth Dissertations

Structure, petrology, and U-Th-Pb geochronology in the Milford (15') quadrangle, New Hampshire.
Petrology -- New Hampshire -- Milford. ; Geological time.
Dartmouth Dissertations

Nucleophilic addition to electron deficient indoles and the synthesis of fused heterocyclic ring systems.
Indole -- Synthesis. ; Heterocyclic compounds -- Synthesis.
The chemistry of indole can be reversed and redirected by the addition of powerful electron-withdrawing groups. Incorporation of a nitro group at C-2 or C-3 renders the adjacent carbon susceptible to nucleophilic attack. Nitro, cyano, and...
Dartmouth Dissertations

Clay mineralogy and geochemistry of soils and sediments with perma frost in interior Alaska.
Clay minerals -- Alaska. ; Soils -- Alaska. ; Frozen ground -- Alaska.
Dartmouth Dissertations

The glucose transporter is a glycoprotein of Mr 55,000 and is probably not phosphorylated in response to biological activators of transport.
Glycoproteins. ; Monoclonal antibodies. ; Immune response.
Dartmouth Dissertations

Migmatite systematics and geology : Carter Dome-Wild River Region White Mountains New Hampshire.
Migmatite -- New Hampshire. ; Geology -- New Hampshire.
Dartmouth Dissertations

Isolation and characterization of essential genes of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA.
Messenger RNA. ; Saccharomyces cerevisiae. ; Cytoplasm.
Dartmouth Dissertations

An effective distributed caching strategy for partial result reuse for discrete optimization problems.
Evolutionary computation. ; Cache memory. ; Mathematical optimization. ; Protein folding -- Computer simulation.
Evolutionary Computation (EC) is one of the most advanced computational techniques. It has been frequently and successfully used to find good solutions to many complicated optimization problems with limited computational resources. EC is the...
Dartmouth Dissertations

An effective distributed caching strategy for partial result reuse for discrete optimization problems.
Evolutionary computation. Cache memory. Mathematical optimization. Protein folding -- Computer simulation.
Evolutionary Computation (EC) is one of the most advanced computational techniques. It has been frequently and successfully used to find good solutions to many complicated optimization problems with limited computational resources. EC is the...
Dartmouth Dissertations

Analysis of inpatient surveillance data for automated classification of deterioration.
Problem Statement Patient safety in the modern hospital is supported by multiple human and technological systems, and this type of high-risk/high-complexity domain requires multiple layers of protection against harm. This fault-tolerant approach is...
Dartmouth Dissertations

High resolution infrared spectroscopy and photolysis of solutes in cryogenic solids.
Infrared spectroscopy. ; Photodissociation. ; Argon. ; Nitrogen.
Dartmouth Dissertations

Early earth and solar system evolution: insights from strontium, barium, neodymium, and samarium isotopes.
Chondrites (Meteorites). ; Mantle plumes. ; Samarium-neodymium dating. ; Strontium -- Isotopes. ; Barium -- Isotopes. ; Solar system. ; Earth -- Mantle.
Dartmouth Dissertations

Neo-architectonics computer-aided histological examination of the human visual cortex.
Visual cortex -- Imaging. ; Visual cortex -- Histology. ; Image processing -- Digital techniques.
Functional neuroimaging has confirmed a high degree of localization of function in the cerebral cortex of man. In contrast, microstructural analysis has contributed very little to the topographical characterization of cortical areas. In this work I...
Dartmouth Dissertations

Imaging performance in advanced small pixel and low light image sensors / by Leo Anzagira
The proliferation of mobile devices and other consumer products has greatly expanded the market for CMOS image sensors. This in turn has promoted a trend of continued improvement in image sensor performance, as companies seek to gain an advantage...
Dartmouth Dissertations

Isotopic phase separation in dilute solid mixtures of Helium-4 in Helium-3.
Helium -- Isotopes. ; Isotope separation.
Dartmouth Dissertations

Dependence of snow thermal and electrical conductiveness on microstructure.
Snow -- Thermal properties. ; Snow -- Electric properties. ; Microstructure.
Dartmouth Dissertations

Discovering MII1 regulated pathways in hematopoietic stem cells.
Hematopoietic stem cells. ; Hematopoietic stem cell disorders -- Genetic aspects. ; Genetic transcription -- Regulation. ; Leukemia -- Genetic aspects. ; Cell proliferation. ; Myeloid-Lymphoid Leukemia Protein -- genetics.
Hematopoietic stem cells (HSCs) balance self-renewal with the continuous production of the suitable numbers of lineage-restricted progenitor cells. In this work we demonstrate that the Mixed lineage leukemia 1 (Mll1) gene is essential for this...
Dartmouth Dissertations

Development and application of a dual-excitation, digital imaging, fluorescence microscope to investigate parathyroid hormone-stimulated calcium transport in kidney distal tubule cells.
Fluorescence microscopy. ; Calcium -- Physiological transport -- Measurement. ; Renal tubular transport -- Measurement.
Dartmouth Dissertations

Firefighting on geometric graphs.
Graph theory. ; Infinite groups. ; Geometrical constructions. ; Geometry Plane.
In the Firefighter Problem, a fire starts at a vertex of a graph, and in discrete time units, it spreads from burned vertices to their neighbors, unless they are protected by one of the f firefighters that are deployed every turn. Once burned or...
Dartmouth Dissertations

Metamorphism in east central Vermont.
Metamorphism (Geology) -- Vermont. ; Nappes (Geology) -- Vermont.
Dartmouth Dissertations

Th-dependent B cell activation.
B cells. ; T cells. ; Cell interaction. ; Body fluids -- Immunology.
Dartmouth Dissertations

Hamiltonians, invariants and magnetic field-line topology.
Magnetic fields -- Mathematical models. ; Hamiltonian systems. ; Invariants.
Dartmouth Dissertations

Effects of selenium deficiency on deiodinase expression and thyroid hormone economy in the rat during development.
Thyroid hormones -- Physiological effect. ; Selenium -- Physiological effect. ; Thyroid hormones -- Synthesis.
The iodothyronine deiodinases, D1, D2, and D3, play a crucial role in determining the circulating and intracellular levels of active and inactive thyroid hormone (TH), and thus have a major effect on TH action during development and adulthood. The...
Dartmouth Dissertations

Quantitative analysis of EEG for the detection and localization of seizures in patients with medically refractory epilepsy.
Electroencephalography -- Data processing. ; Epilepsy -- Diagnosis. ; Signal processing -- Mathematics. ; Time-series analysis. ; Wavelets (Mathematics).
Visual interpretation of the EEG associated with an epileptic seizure (ictal EEG) can be cumbersome and sometimes misleading, due to rapid seizure spread, limited spatial resolution and the fact that signals of interest are often obscured by...
Dartmouth Dissertations

Providing evidence and measurement tools to support health care reform in communities.
Community health services -- United States -- Evaluation. ; Health care reform -- United States. ; Medical care -- United States -- Evaluation. ; Evidence-based medicine.
Dartmouth Dissertations

Isolation of interleukin-2-induced immediate-early genes.
Interleukin-2.
Dartmouth Dissertations

Characterization of COPII vesicle proteins involved in sorting between the endoplasmic reticulum and golgi apparatus in Sacch[a]romyces cerevisiae.
Membrane proteins -- Physiological transport. ; Carrier proteins. ; Biological transport -- Regulation. ; Saccharomyces cerevisiae -- Cytology. ; Golgi apparatus. ; Endoplasmic reticulum.
Intracellular transport between the ER and Golgi is mediated by vesicles that bud from donor membranes and then fuse with acceptor membranes. Bi-directional vesicle transport maintains distinct organelle composition through a process known as...
Dartmouth Dissertations

Plasmodium falciparum SERA protein transgenics used in the study of parasite immunobiology and drug resistance.
Plasmodium falciparum -- Immunological aspects. ; Plasmodium falciparum -- Genetics. ; Toxoplasma gondii -- Genetics. ; Serine proteinases. ; Transgenic organisms. ; Drug resistance in microorganisms -- Genetic aspects.
Genetic and immunological tools have been used to study two protozoan parasites, Plasmodium falciparum and Toxoplasma gondii. Toxoplasma gondii provides an excellent model for the study of protozoan parasite biology. Plasmodium falciparum causes...
Dartmouth Dissertations

Probing a receptor-binding domain of interleukin-2 by combinatorial cassette mutagenesis.
Interleukin-2. ; Mutagenesis.
Dartmouth Dissertations

Synthetic approaches to indolo[2,3-a]carbazole alkaloids.
Indole alkaloids -- Synthesis. ; Carbazole.
Dartmouth Dissertations

A benzonorbornyl model system for the study of carbocation-[pi] interactions.
Carbocations -- Reactivity. ; Aromatic compounds -- Reactivity.
An important mode of stabilization of cations in biochemical reactions is interaction with the π systems-of aromatic residues. As part of an investigation of the interaction of carbocations with aromatic π systems, a study of various model...
Dartmouth Dissertations

Some results on Souslin trees.
Trees (Graph theory). ; Set theory.
Dartmouth Dissertations

The role of dichoptic brightness in binocular vision.
Binocular vision.
Dartmouth Dissertations

Effect of increased hemoglobin oxygen affinity on oxygen transport and its regulation in the rat.
Hemoglobin. ; Oxygen -- Physiological transport. ; Rats.
Dartmouth Dissertations

Patient outcomes and clinical decision making in aortic valve replacement.
Outcome assessment (Medical care). ; Aortic valve -- Surgery -- Complications. ; Aortic valve -- Surgery -- New England. ; Cardiovascular instruments Implanted.
Aortic valve disease is a frequent and serious disorder. Although aortic valve replacement (AVR) is arguably the only effective treatment, important issues remain unresolved in the care of patients with this disease. Recent studies have focused...
Dartmouth Dissertations

A test apparatus for frozen soil in complex stress.
Frozen ground. ; Soil mechanics.
Dartmouth Dissertations

Novel synthetic approaches to polycyclic aromatic hydrocarbons.
Polycyclic aromatic hydrocarbons -- Synthesis.
This research attempts to combine known methodology with new chemistry towards the preparation of extended polycyclic aromatic hydrocarbons (PAH). The generation and Diels-Alder trapping of 1,7- and 2,6-naphthalene bisarynes was attempted for the...
Dartmouth Dissertations

Density-dependent dynamics in a tropical rain forest canopy tree.
Dipterocarpaceae -- Ecology -- Indonesia -- Kalimantan Barat. ; Rain forest ecology -- Indonesia -- Kalimantan Barat. ; Herbivores -- Ecology.
A decline in population growth as the abundance of a species increases can stabilize population size. In Western Borneo, I found evidence for such density dependence in juveniles of the genus Shorea (Dipterocarpaceae) that dominates southeast...
Dartmouth Dissertations

The synthesis and characterization of transition metal vinylidene complexes.
Vinylidene complexes. ; Transition metal compounds. ; Organometallic compounds.
Dartmouth Dissertations

Carbon-fluorine bond activation of iridium (III) compounds induced by acids and reducing agents.
Organoiridium compounds -- Synthesis. ; Organofluorine compounds -- Synthesis. ; Ligands.
Dartmouth Dissertations

The formation of chloroform and related products from the chlorination of polyhydroxybenzenes and diketones in dilute aqueous solution.
Chloroform. ; Chlorination.
Dartmouth Dissertations

Market-based control of mobile-agent systems.
Mobile agents (Computer software). ; Resource allocation -- Mathematical models. ; Computer networks -- Economic aspects.
Modern distributed systems scatter sensors, storage, and computation throughout the environment. Ideally these devices communicate and share resources, but there is seldom motivation for a device''s owner to yield control to another user. We...
Dartmouth Dissertations

Large-scale structure of the universe: a clustering analysis.
Cosmology -- Mathematical models. ; Galaxies -- Clusters -- Mathematical models. ; Dark matter (Astronomy).
Dartmouth Dissertations

Infinitary languages, generalized quantifiers, and generalized products.
Infinitary languages. ; Logic.
Dartmouth Dissertations

Random quantum dynamics : from random quantum circuits to quantum chaos.
Quantum computers. ; Quantum chaos. ; Many-body problem. ; Hamiltonian systems.
Dartmouth Dissertations

High-throughput analysis of antigen-specific antibody effector function from polyclonal Ig / by Eric Brown
Antibodies are known to be a primary correlate of protection in almost all current vaccines, and thus evaluating the antibody response is of critical importance in attempting to predict the efficacy of novel vaccine candidates. Historically...
Dartmouth Dissertations

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