Dartmouth Digital Library Program

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Combined MRI and near-infrared spectroscopy for increased specificity of breast cancer imaging / by Michael A. Mastanduno.
A yearly breast contrast-MR scan is recommended to high-risk women because of MR's high sensitivity to breast tumors. However, breast contrast-MR yields a high number of false positives that lead to expensive and sometimes unnecessary biopsy...
Dartmouth Dissertations

Understanding the vulnerabilities of tumors : a network-based approach to drug target discovery / by Nadia M. Penrod.
The demand for novel molecularly targeted drugs will continue to rise as we make progress toward personalizing cancer treatments to the molecular signatures of individual tumors. While the collection and analysis of genomic data has become routine,...
Dartmouth Dissertations

Advancement of magnetic resonance poroelastography for applications in brain imaging / by Adam J. Pattison.
Brain tissue mechanics are an important biomarker for neurological disorders, yet methods to obtain tissue information yield inconsistent conclusions. These techniques can be invasive or require excised tissue, where tissue function is altered from...
Dartmouth Dissertations

Sampling for complexity in rendering / by Jiawei Ou.
As the visual effect and movie industries are striving for realism and high fidelity images, physically based lighting, global illumination, realistic materials, and highly tessellated geometry are gradually accepted and used in movie and game...
Dartmouth Dissertations

Magnetic nanoparticle hyperthermia as an adjuvant cancer therapy with chemotherapy / by Alicia Ailie Petryk.
Magnetic nanoparticle-based hyperthermia for cancer treatment is a promising technology, particularly when applied as part of an adjuvant strategy with established cancer therapies (chemotherapy, radiation and surgery). In Europe, early clinical...
Dartmouth Dissertations

A computational study of radio relics in galaxy cluster mergers / by Dane Patrick Owen.
Radio relics are extended regions of synchrotron radio emission that have been found in the outskirts of a few dozen galaxy clusters. Relics are often associated with clusters undergoing merger activity. They are not associated optically with a...
Dartmouth Dissertations

A framework of computational opinions / by Fei Yu.
We have a limited understanding of how an opinion is originated, how an opinion and information supporting and explaining it gets conveyed, and how the communicated opinion is perceived and processed by others. One direction of current research...
Dartmouth Dissertations

Security-policy analysis with eXtended unix tools / by Gabriel A. Weaver.
During our fieldwork with real-world organizations---including those in Public Key Infrastructure (PKI), network configuration management, and the electrical power grid---we repeatedly noticed that security policies and related security artifacts...
Dartmouth Dissertations

Silicon/silicon-germanium quantum dots with single-electron transistor charge sensors / by Mingyun Yuan.
Si/SiGe quantum dots (QDs) are promising candidates for spin-based quantum bits (qubits) as a result of the reduced spin-orbit coupling as well as the Si isotopes with zero nuclear spin. Meanwhile qubit readout is a challenge related to...
Dartmouth Dissertations

Noninvasive fluorescence monitoring for functional assessment of murine glioma treatment.
Gliomas -- Immunotherapy -- Evaluation. Fluorescence spectroscopy. Diagnosis.
Molecular optical imaging in vivo has potential for functional assessment of tumor tissue at the cellular and subcellular level. Advances in biological understanding of genomics and proteomics have increased the knowledge of possible cellular...
Dartmouth Dissertations

The ecology and bioenergetics of the northern black-throated blue warbler.
Wood warblers.
Dartmouth Dissertations

Energy gaps and infrared spectra by electron tunneling.
Tunneling (Physics); Energy levels (Quantum mechanics).
Dartmouth Dissertations

Automatic spectral classification.
Stars -- Spectra -- Classification. Stars -- Open clusters.
Dartmouth Dissertations

C.O.A.L.1: a dynamic model for the analysis of United States energy policy.
Energy policy -- United States -- Mathematical models.
Dartmouth Dissertations

Examining auroral downward current region processes using ground based data.
Auroras -- Alaska -- Observations. Magnetospheric currents.
This thesis presents data from ground camera observations of the aurora conducted from Alaska during the winters of 2005 through 2007. In conjunction with these camera observations, conjugate radar observations of the auroral ionosphere were...
Dartmouth Dissertations

Some partition theorems and ultrafilters on w [i.e. omega].
Partitions (Mathematics) Ultrafilters (Mathematics).
Dartmouth Dissertations

Periodic spectral variation in Cygnus X-2 and Scorpius X-1.
Stars -- Spectra.
Dartmouth Dissertations

The synthesis and chemistry of novel cyclic perfluoromethyl-substituted molecules.
Fluorine compounds.
Dartmouth Dissertations

Studies of equilibrium and dynamic properties of polymers.
Polymers. Chemical equilibrium.
Dartmouth Dissertations

Forest structure and atmospheric interactions : predictive models for subalpine balsam fir forest
Forest hydrology -- Mathematical models; Forest Meteorology -- Mathematical models; Balsam fir
Dartmouth Dissertations

Drift waves in a nonuniformly rotating plasma column.
Drift waves. Rotating plasmas.
Dartmouth Dissertations

Characterization of a Cerenkov maser
Masers; Electromagnetism; Microwave devices
Dartmouth Dissertations

Evaluation and engineering of Saccharomyces cerevisiae for cellulase expression and growth on insoluble cellulose.
Saccharomyces cerevisiae -- Genetics. Cellulase -- Biotechnology. Cellulose -- Biotechnology. Biomass conversion -- Technological innovations.
Dartmouth Dissertations

On the implementation of ALGOL 68.
ALGOL (Computer program language);Computer programming.
Dartmouth Dissertations

Excitatory and inhibitory properties of human facial expressions of emotion.
Facial expression. Emotions.
Dartmouth Dissertations

Quantitative study of perceptual vector analysis.
Vector analysis. Motion perception (Vision)
Dartmouth Dissertations

Dissecting the heterogeneity of breast tumor subtypes / by Nima Pouladi.
Breast cancer is the most common cancer in women. The discovery of breast tumor subtypes and the subsequent development of treatments aimed at them has allowed a reduction in the mortality of breast cancer. However, tumors with similar...
Dartmouth Dissertations

Access control in and for the real world / by Sara Sinclair.
Access control is a core component of any information-security strategy. Researchers have spent tremendous energy over the past forty years defining abstract access-control models and proving various properties about them. However, surprisingly...
Dartmouth Dissertations

Group-aware stream filtering.
Streaming technology (Telecommunications). Computer networks -- Monitoring. Multicasting (Computer networks). Electronic data processing -- Distributed processing.
Recent years have witnessed a new class of monitoring applications that need to continuously collect information from remote data sources. Those data sources, such as web click-streams, stock quotes, and sensor data, are often characterized as...
Dartmouth Dissertations

System and methodology for receptor-level fluorescence imaging during surgery / by Kristian Sexton.
Fluorescence molecular imaging will have an important clinical impact in the area of guided oncology surgery, where emerging technologies are poised to provide the surgeon with real-time molecular information to guide resection, using targeted...
Dartmouth Dissertations

Understanding PDZ affinity and selectivity: all residues considered / by Jeanine F. Amacher.
PDZ protein-protein interaction domains recognize short linear motif (SLiM) sequences typically at the extreme C-terminus of a target protein. These domains often act as scaffolds, connecting target proteins to additional interaction and catalytic...
Dartmouth Dissertations

Combined digital breast tomosynthesis and near-infrared spectral tomography for breast lesion characterization / by Kelly E. Michaelsen.
Annual screening mammograms are recommended for all women above 40 years of age for early detection of breast cancer, and are known to improve cancer mortality rates. However, mammography is hampered by low sensitivity and a high rate of false...
Dartmouth Dissertations

Traces on graph algebras / by Danny W. Crytser.
This thesis contains material relating to two separate subjects. The first section determines when the C*-algebra affiliated to a directed graph has continuous trace. We use groupoid methods and the focus is on producing conditions on a graph that...
Dartmouth Dissertations

Magnetic susceptibility imaging of magnetic nanoparticles / by Bradley W. Ficko.
Magnetic susceptibility imaging of magnetic nanoparticles (mNPs) has many potential applications in biomedicine such as contrast enhanced imaging and image guidance for magnetic hyperthermia therapy. This thesis describes three imaging methods...
Dartmouth Dissertations

Modflows : methods for studying and managing mesh editing workflows / by Jonathan D. Denning.
At the heart of computer games and computer generated films lies 3D content creation. A student wanting to learn how to create and edit 3D meshes can quickly find thousands of videos explaining the workflow process. These videos are a popular...
Dartmouth Dissertations

Multimodal electroencephalography and near-infrared spectroscopy neuroimaging measurement and analysis / by Paolo Giacometti
This project focuses on the development of research tools and methods that are used to study the relationship between neural activity and subsequent hemodynamic responses in the human brain. This relationship, referred to as neurovascular coupling,...
Dartmouth Dissertations

Opinion dynamics in social networks / by Qi Gu.
Opinion dynamics is a complex procedure that entails a cognitive process when it deals with how a person integrates influential opinions to form revised opinion. Early research on opinion formation and social influence can be traced back to the...
Dartmouth Dissertations

Towards the experimental verification of macroscopic phenomena in quantum electrodynamics.
Casimir effect. Zero-point field. Electric conductivity. Quantum electrodynamics.
The Casimir force arises from an alteration of boundary condition in vacuum and is often regarded as a manifestation of quantum zero point energy. Considerable progress has been made in the last decade with an impressive achievement of experimental...
Dartmouth Dissertations

The RNA binding landscape of the histone stem-loop binding protein / by Lionel (Lee) Brooks 3rd.
RNA binding proteins are fundamental components of crucial biological processes in all domains of life. The development of techniques to study RNA binding protein complexes is, therefore, broadly impactful. I employed multiple genome-wide...
Dartmouth Dissertations

Quantifying optical tomography methods for biomolecular sensing / by Jennifer-Lynn H. Demers.
Diffuse optical imaging techniques can be combined with standard imaging technologies such as computed tomography (CT) and magnetic resonance (MR) imaging to allow measurement of spectroscopic signals pertaining to the molecular components of...
Dartmouth Dissertations

Late glacial and holocene fluctuations of local glaciers and the Greenland Ice Sheet eastern and western Greenland / by Laura B. Levy.
The Greenland Ice Sheet (GrIS) is responding sensitively to climate change and its meltwater has the potential to influence global sea level. Recently, large changes in the GrIS have occurred including increased velocities of outlet glaciers and...
Dartmouth Dissertations

Secure collaboration in an open environment.
Internet -- Security measures. Public key infrastructure (Computer security). Digital signatures. Peer-to-peer architecture (Computer networks) -- Security measures.
The Internet has become a virtual place where people not only operate in isolation but also interact with other Internet users. Collaborative systems are becoming more popular. Applications now being introduced could provide better remote education...
Dartmouth Dissertations

Integration of machine learning network science and pathway analysis in genetic epidemiology / by Qinxin Pan.
Although genome-wide association studies (GWAS) and other high-throughput initiatives have led to an information explosion in human genetics and genetic epidemiology, the mapping from genotype to phenotype remains challenging as most of the...
Dartmouth Dissertations

K-Theory for twisted groupoid C*-algebras / by Elizabeth Gillaspy.
This thesis constitutes the first steps in the author's program to investigate the question of when a homotopy of 2-cocycles ω = {ω[subscript t]}[subscript t∊[0,1]] on a locally compact Hausdorff groupoid Ɠ induces an isomorphism of the...
Dartmouth Dissertations

Thermodynamic and spectroscopic studies of metalloprotein stability ligation and reactivity / by George P. Lisi III.
Metal ions confer structural stability and reactivity to a large number of proteins that use the amino acids histidine (His) and cysteine (Cys) to form stable metal-ligand complexes. The stability of metal-His and metal-Cys interactions and their...
Dartmouth Dissertations

Methods for efficient object categorization detection scene recognition and image search / by Alessandro Bergamo.
In the past few years there has been a tremendous growth in the usage of digital images. Users can now access millions of photos, a fact that poses the need of having methods that can efficiently and effectively search the visual information of...
Dartmouth Dissertations

Sexual selection and sexual conflict in Anolis lizards : from molecules to populations / by M. Catherine Duryea.
Sexual selection is a driver of biodiversity and creates spectacular forms of variation. However, only recently have we begun to understand how this variation operates on the postcopulatory level and how cryptic mechanisms affect male-male...
Dartmouth Dissertations

Computational methods for the discovery and application of protein sequence-structure-function relationships / by Lu He.
Proteins are ubiquitous in cells and are essential to a wide range of biological processes. Since existing proteins occupy only a small portion of the space of possible amino acid composition, understanding their sequence-structure-function...
Dartmouth Dissertations

The role of cell stress signalling in the induction of [gamma]-globin gene expression / by Emily K. Schaeffer.
Increased fetal hemoglobin (HbF) expression is beneficial for [beta]-hemoglobinopathy patients; however, most inducing agents do not possess the ideal combination of efficacy, safety and availability. Better understanding the mechanisms involved in...
Dartmouth Dissertations

Aligned hierarchies for sequential data / by Katherine M. Kinnaird.
We present aligned hierarchies, a novel solution to the dimension reduction problem, representing high-dimensional and noisy sequential data as a low-dimensional object that encodes relevant information. In this thesis, we motivate our presentation...
Dartmouth Dissertations

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