Autonomous off-road navigation in unstructured, terrain can encounter mobility difficulties even when the surface that the vehicle is driving over is level and free from obstacles. Mobility challenges result from soil characteristics that prevent...
The integration of visual and auditory events is thought to require a joint representation of visual and auditory space in a common reference frame. We investigated the coding of visual and auditory space in the lateral and medial intraparietal...
Electric fields in the high-latitude regions of Earth's ionosphere are an important component of the coupled magnetosphere-ionosphere-thermosphere system. Characterizing the average behavior of these fields (or the corresponding drifts) is useful...
Access control is a core component of any information-security strategy. Researchers have spent tremendous energy over the past forty years defining abstract access-control models and proving various properties about them. However, surprisingly...
Pseudomonas aeruginosa is a virulent opportunistic pathogen that is frequently cultured from infectious sites, and is estimated to cause ~12% of nosocomial infections worldwide [1]. P. aeruginosa infections occur in a majority of adults with the...
Proteins are ubiquitous in cells and are essential to a wide range of biological processes. Since existing proteins occupy only a small portion of the space of possible amino acid composition, understanding their sequence-structure-function...
Nutrients play fundamental roles in biological systems, affecting plant growth and quality, community structure, and species interactions. Although the effects of nutrients on primary and secondary production have been well documented, their...
Some biomacromolecules require a metal co-factor to stabilize their physiologically active three-dimensional structure. The fundamental thermodynamic values of the binding of metal ions, particularly Zn2+, to a set of biomacromolecules have been...
Humans have a seemingly unique capacity to reflect upon information about the self to form evaluative attitudes that influence their quality of life and predict mental health outcomes. While psychologists have devoted decades of research to the...
CD4+ T cells are critical for the control of virus infections, memory cell formation and immune surveillance. Epstein-Barr virus and Kaposi’s sarcoma-associated herpesvirus are two γ-herpesviruses identified in humans and are strongly associated...
Understanding mercury (Hg) and lead (Pb) accumulation and retention in forest soils is needed to reduce their negative impacts on human and wildlife health. In addition, mercury and lead can be used to characterize the role of soil in terrestrial...
The new APM South Equatorial Strip Catalog $({-}17\sp\circ.5<\delta<2\sp\circ.5)$ is used to select a sample of early-type galaxies in three directions: (1) 15h10-16h10; (2) 20h30-21h50; (3) 00h10-01h30. The distances and peculiar motions of...
Sensing light from the environment using photoreceptors is of great adaptive significance to eukaryotes. A prominent feature of the photochemistry of these receptors is the photocycle length, the time taken to decay from the initial signaling light...
The oculomotor system needs up-to-date information about eye position in order to make accurate saccades to stimuli in the environment. This thesis investigated how well the oculomotor system uses information about eye position to make a variety of...
Introduction. Nosocomial sepsis in extremely low birth weight (ELBW) infants 501-1000 grams is associated with increased mortality risk, prolonged hospitalization, and increased costs of care. Purpose. The purpose of this thesis was to evaluate the...
DC-to-DC converters -- Design and construction. Electric inductors -- Design and construction. Thin film devices -- Design and construction. Microprocessors -- Power supply. Microfabrication. Transients (Dynamics).
Steep terrain produces a topographic effect in digital satellite data that can make it difficult to distinguish changes in vegetation species or health from changes in illumination geometry. A multiple linear regression analysis of direct solar...
Chronic neuropathic pain is a debilitating condition that exacts an emotional and physical toll on its sufferers and their family as well as an enormous monetary toll on society. Neuropathic pain can arise following nerve injury induced by trauma,...
Space perception. ; Motion perception (Vision). ; Vestibular apparatus.
Head Direction (HD) cells are neurons located primarily in the limbic system that fire as a function of directional heading in the horizontal, or yaw, plane in the freely moving animal. Our hypothesis is that the HD signal is the result of two...
Outcome assessment (Medical care). ; Aortic valve -- Surgery -- Complications. ; Aortic valve -- Surgery -- New England. ; Cardiovascular instruments Implanted.
Aortic valve disease is a frequent and serious disorder. Although aortic valve replacement (AVR) is arguably the only effective treatment, important issues remain unresolved in the care of patients with this disease. Recent studies have focused...
Large-scale (12,000 liter) and small-scale (3.78 liter) field enclosure experiments were conducted to evaluate the intensity and nature of competition among the planktonic cladoceran grazers of a mesotrophic Vermont lake: Bosmina longirostris,...
There are five ethylene receptors (ETR1, ERS1, ETR2, ERS2, and EIN4) in Arabidopsis. In this study, I tested the hypothesis that ethylene receptors mediate ethylene signaling through protein-protein interactions. First, I demonstrated that ethylene...
Arabidopsis -- Effect of metals on. ; Zinc -- Physiological transport. ; Iron -- Physiological transport. ; Plants -- Effect of iron on. ; Plants -- Effect of zinc on.
Iron and zinc deficiency commonly limit plant growth and crop yields. Furthermore, deficiencies in both of these micronutrients are common throughout the world, particularly in developing countries where people may only consume simple diets...
The use of stochastic modeling techniques has provided many insights into the processing architecture of the oculomotor system. The present work evaluates the issue of saccadic target selection using these techniques. Observers were presented with...
Photodynamic therapy (PDT) is used to cause specific tissue destruction, using photochemical reactions that result from light excitation of photosensitizer, which has localized in the target tissue. The process of photosensitizer photobleaching was...
Intestine, Large -- Cancer -- Epidemiology. ; Intestine.
Colorectal cancer is the fourth most common cancer diagnosis and the second leading cause of cancer-related death in the United States. Most colorectal cancers are believed to develop from precursor lesions known as colorectal adenomas....
Brain tumors account for ~2% of all cancers, with gliomas accounting for ~70% of all brain tumors. Evidence suggests that extent of resection provides both a quality of life and survival benefit to patients. Recent work has shown the utility of...
For a local field K, we study the affine buildings Ξ n and Δ n naturally associated to SL n ( K ) and Sp n ( K ), respectively. Since Sp n ( K ) is a subgroup of SL 2 n ( K ), we investigate properties of a natural embedding of Δ n in Ξ 2 n ....
Digital video -- Analysis. Forensic sciences. Image processing -- Digital techniques.
We present new forensic tools that are capable of detecting traces of tampering in digital video without the use of watermarks or specialized hardware. These tools operate under the assumption that video contain naturally occurring properties which...
Accurate segregation of meiotic chromosomes requires that sister-chromatids remain physically associated from the time of their synthesis during S phase until they segregate toward opposite poles at anaphase II. In Drosophila melanogaster meiosis,...
Patients -- Decision making. Patients -- Attitudes. Motivation (Psychology) -- Social aspects. Preferences (Philosophy) Medical care -- Evaluation. Medical care -- Research -- Methodology. Medical care -- Decision making.
Statement of Problem
Characterizing the public's preferential attitudes towards relatively more-/less-intense elective options in ""preference-sensitive"" health care situations is particularly relevant for the prioritization policies of...
Glutamic acid -- Receptors. Ion channels -- Molecular aspects. Ligand binding (Biochemistry).
Medical Term: Glutamates.
AMPA receptors are glutamate-gated ion channels that mediate most of the excitatory synaptic signals in the central nervous system. They form tetrameric assemblies that are combinations of the subunits GluR1-4, each of which contains a...
Pseudomonas aeruginosa is an opportunistic pathogen of humans and the leading cause of mortality in patients with the inherited disorder cystic fibrosis (CF). The focus of the studies presented herein was characterization of the regulation and...
Urban and suburban development is a dominant factor driving ecological processes at local and regional scales and its impacts on biodiversity and ecosystem services are alarming. Pollinators, especially bees, and the ecosystem services they...
A yearly breast contrast-MR scan is recommended to high-risk women because of MR's high sensitivity to breast tumors. However, breast contrast-MR yields a high number of false positives that lead to expensive and sometimes unnecessary biopsy...
Continual improvements to clinical breast imaging technologies have led to ever earlier detections and increasingly accurate localizations of female breast cancers. While these advancements have certainly improved the prognoses of many patients,...
As the visual effect and movie industries are striving for realism and high fidelity images, physically based lighting, global illumination, realistic materials, and highly tessellated geometry are gradually accepted and used in movie and game...
MicroRNA-10b (miR-10b) is considered a marker of disease aggressiveness in pancreatic ductal adenocarcinoma (PDAC), in view of the fact that lower levels of miR-10b are associated with better response to neoadjuvant therapy, likelihood of surgical...