Though the science of invasion biology has over a 50-year history it still struggles with clearly documenting the mechanisms and impacts of plant invasions. Numerous observational studies find associations between plant invasions and largescale...
Type 4 prepilins and prepilin-like-proteins are secreted by a wide range of bacterial species and are required for a variety of functions including type 4 pilus (Tfp) formation, toxin and other enzyme secretion, gene transfer, and biofilm...
Accurate chromosome segregation during mitosis and meiosis requires that sister-chromatid cohesion hold sisters together until the appropriate time. In addition, meiotic cohesion is necessary for normal synaptonemal complex (SC) and homologous...
Neural stem cells (NSCs) have the capacity to proliferate and give rise to multiple major central nervous system cell types and represent a possible cell of origin in gliomagenesis. Deletion of the tumor suppressor gene Tp53 (p53) results in...
Functional magnetic resonance imaging (fMRI) is an important tool for understanding neural mechanisms underlying human brain function. Most fMRI studies use limited sets of well-controlled stimuli to understand neural systems in isolation. The...
This project focuses on the development of research tools and methods that are used to study the relationship between neural activity and subsequent hemodynamic responses in the human brain. This relationship, referred to as neurovascular coupling,...
Candida albicans is a fungal species that naturally exists as a commensal member of the human microbiota, but can assume a pathogenic lifestyle and subsequently induce life-threatening systemic infections. The ability of the fungus to grow in...
The oculomotor system needs up-to-date information about eye position in order to make accurate saccades to stimuli in the environment. This thesis investigated how well the oculomotor system uses information about eye position to make a variety of...
Steep terrain produces a topographic effect in digital satellite data that can make it difficult to distinguish changes in vegetation species or health from changes in illumination geometry. A multiple linear regression analysis of direct solar...
Retinoids -- Mechanism of action. ; Post-translational modification. ; Tretinoin -- Therapeutic use. ; Lungs -- Cancer -- Chemoprevention.
The retinoids--natural and synthetic derivatives of vitamin A--are active in cancer therapy and chemoprevention. The signals that underlie retinoid clinical activity are triggered by induction of retinoid target genes. Therefore, a greater...
Musical intervals and scales -- Psychological aspects. ; Music -- Psychological aspects. ; Chords (Music) -- Psychological aspects. ; Stability.
In Western tonal music, the major mode is associated with positive emotions, and the minor mode is associated with negative emotions. Although this is a highly salient distinction, it is poorly understood. In 9 experiments, participants made...
Non-ribosomal peptide synthetases (NRPS) are a family of enzymes that assemble a variety of pharmacologically interesting polypeptides from canonical and non-canonical amino acids. The identity and connectivity of the monomers in the final product...
Topological graph theory. Aperiodicity. Paths and cycles (Graph theory)
The condition ""every cycle has an entry"" first appeared in the literature in Kumjian, Pask, and Raeburn's paper on Cuntz-Krieger algebras of directed graphs, where it was called Condition (L). It provides a necessary condition for simplicity of...
Classic studies demonstrated that when cells in different cell cycle phases are fused, nuclei cohabiting in a common cytoplasm synchronize their division cycles. Cytoplasmic factors, now known to be cyclin/cyclin dependent kinase (CDK) complexes,...