Dartmouth Digital Library Program

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The population dynamics, bioenergetics, and nutrient cycling of three species of mice in the Hubbard Brook Experimental Forest, New Hampshire, U.S.A
Mice; Forest ecology -- New Hampshire. ; Animal ecology -- New Hampshire
Dartmouth Dissertations

The effect of human breast milk on cell-free and cell-associated HIV-1 infection.
HIV infections -- Immunological aspects. Breast milk -- Physiological effect.
Human breast milk is a highly complex secretion that serves as a source of nutrients and protective immune factors to the growing infant whose immune system is still developing. Epidemiological studies of infants born to Human Immunodeficiency...
Dartmouth Dissertations

A dynamically refocusable sampling infrastructure for 802.11 networks.
Telecommunication -- Traffic -- Measurement -- Statistical methods. IEEE 802.11 (Standard). Universities and colleges -- Computer networks -- New Hampshire -- Hanover -- Case studies.
The edge of the Internet is increasingly wireless. Enterprises large and small, homeowners, and even whole cities have deployed Wi-Fi networks for their users, and many users never need to--or never bother to--use the wired network. With the advent...
Dartmouth Dissertations

Sexual selection and sexual conflict in Anolis lizards : from molecules to populations / by M. Catherine Duryea.
Sexual selection is a driver of biodiversity and creates spectacular forms of variation. However, only recently have we begun to understand how this variation operates on the postcopulatory level and how cryptic mechanisms affect male-male...
Dartmouth Dissertations

An evaluation of adrenergic and sympathetic influences modulating behavior in an animal model of neuropathic pain.
Neuralgia -- Animal models. Allodynia -- Animal models. Adrenergic mechanisms. Sympathetic nervous system.
Dartmouth Dissertations

A mechanistic investigation of the ring expansion of vinylcyclopropenes to metallacyclohexadienes and cyclopentadienyl complexes through the use of isotopically labelled ligands.
Organometallic chemistry. Isomerization. Organoiridium compounds. Organoiron compounds. Organorhodium compounds.
Dartmouth Dissertations

Efficient stabilization methods for fast polynomial transforms
Computer algorithms. ; Transformations (Mathematics). ; Matrix derivatives.
Dartmouth Dissertations

Serotonin signaling in the nucleus tractus solitarius modulates the larybgeal chemoreflex : implications for sudden infant death syndrome / by William T. Donnelly
Sudden infant death syndrome (SIDS) occurs when a sleeping infant experiences a challenge to cardiorespiratory homeostasis which it fails to overcome. Analyses of brain tissue from SIDS cases from around the world consistently show abnormalities in...
Dartmouth Dissertations

Th-dependent B cell activation.
B cells. ; T cells. ; Cell interaction. ; Body fluids -- Immunology.
Dartmouth Dissertations

Insulin regulation of the glucose transporters in 3T3-L1 adipocytes and BC3H-1 myocytes.
Glucose -- Physiological transport. ; Insulin -- Physiological effect. ; Fat cells. ; Muscle cells.
Dartmouth Dissertations

Study of the molecular mechanism of the Neurospora circadian clock.
Neurospora -- Genetics. ; Neurospora -- Effect of light on. ; Circadian rhythms. ; Proteins -- Synthesis -- Effect of light on. ; Genetic regulation.
The frequency gene and the two proteins it encodes are central components of the Neurospora circadian clock. The frq message and proteins are involved in a negative feedback loop in which FRO represses its own transcript level. Based on this...
Dartmouth Dissertations

Galley: a new parallel file system for scientific applications.
Parallel processing (Electronic computers). ; File organization (Computer science). ; Multiprogramming (Electronic computers). ; Multiprocessors.
Most current multiprocessor file systems are designed to use multiple disks in parallel, using the high aggregate bandwidth to meet the growing I/O requirements of parallel scientific applications. Most multiprocessor file systems provide...
Dartmouth Dissertations

Differentiating and anti-inflammatory activities of the triterpenoid, CDDO: interactions with transcription factors PPARγ and NF-κ B.
Triterpenoid saponins -- Physiology. ; Cell receptors. ; Receptor-ligand complexes. ; NF-kappa B (DNA-binding protein). ; Peroxisomes. ; Nucleophilic reactions. ; Dithiole.
Dartmouth Dissertations

Synthetic approaches to indolo[2,3-a]carbazole alkaloids.
Indole alkaloids -- Synthesis. ; Carbazole.
Dartmouth Dissertations

Structural, stratigraphic, and thermo-chronological evolution of Trinidad.
Geochronometry -- Trinidad and Tobago -- Trinidad. ; Geology Structural -- Trinidad and Tobago -- Trinidad. ; Geology.
Dartmouth Dissertations

Preparation of sterically hindered bis(secondary phosphines) : structure-selectivity relationships in Pt-catalyzed asymmetric phosphination and synthesis and structure of metal-phosphido complexes.
Phosphorus compounds -- Synthesis. ; Metal complexes -- Synthesis. ; Phosphine. ; Phosphides. ; Platinum catalysts. ; Asymmetric synthesis. ; Gold compounds -- Synthesis.
Dartmouth Dissertations

Regulation of human cytochrome P4501A2 gene (CYP1A2) expression: isolation and functional analysis of the 5'-flanking region.
Cytochrome P-450. ; Genetic regulation. ; Genetic transcription.
Dartmouth Dissertations

Syntrophin binds directly to members of the dystrophin family of proteins and exists as a heterogeneous family.
Protein binding. ; Muscle proteins -- Genetic aspects. ; Muscular dystrophy -- Genetic aspects.
Dartmouth Dissertations

The expression and activity of TP63 in the mammary epithelial regenerative hierarchy.
Tumor proteins. ; p53 antioncogene. ; Epithelial cells. ; Mammary glands -- Cytology. ; Stem cells. ; Regeneration (Biology). ; Genetic transcription -- Regulation. ; Cellular signal transduction.
Dartmouth Dissertations

Preparations of oxysterols and derivatives for investigation of cholesterol regulation.
Oxysterols -- Synthesis. ; Oxysterols -- Derivatives -- Synthesis. ; Cholesterol -- Metabolism -- Regulation. ; Cholesterol -- Synthesis -- Regulation.
Dartmouth Dissertations

Retrieval, reconstruction, and response bias: a cognitive neuroscience investigation of false memories.
False memory syndrome. ; Cognitive neuroscience. ; Prefrontal cortex -- Physiology.
Our conscious experience of memory often includes reconstuctions of the past in order to fill the gaps of forgotten events and details. The goal of this thesis is to use the tools of cognitive neuroscience to better understand the cognitive and...
Dartmouth Dissertations

Geology of the Lake Atitlan area, Guatemala : a study of subduction zone volcanism and caldera formation.
Geology -- Guatemala -- Lake Atitlan area; Volcanism -- Guatemala -- Lake Atitlan area; Calderas -- Guatemala -- Lake Atitlan area.
Geological mapping, petrological and geophysical studies in the lake Atitlan area, Guatemala, have revealed four distinct periods of stratovolcano growth, each followed by major silicic eruptions and caldera collapse. The first period (12 - 11 my...
Dartmouth Dissertations

The interplay between GATA4-FOG2 transcriptional regulation and the canonical WNT signaling pathway in mouse organogenesis.
Mice -- Morphogenesis. ; Mice -- Genetics. ; Transcription factors. ; Cellular signal transduction. ; Genetic regulation. ; GATA4 Transcription Factor -- genetics. ; Wnt Proteins -- physiology.
Dartmouth Dissertations

Hormonal and neurochemical determinants of sex differences in chronic radicular pain.
Radiculitis -- Endocrine aspects. Radiculitis -- Sex factors. Radiculitis -- Pathophysiology. Pain -- Sex factors. Progesterone -- Physiological effect. Cellular signal transduction. Neuregulin-1 -- physiology.
Chronic low back pain is a debilitating and devastating disease affecting millions of people worldwide. Considerable evidence indicates that there are sex-related differences in clinical and experimental pain sensitivity in men and women. Women...
Dartmouth Dissertations

Genetic variants among G-protein coupled receptors and implications for cardiovascular disease.
G proteins -- Receptors. Cardiovascular system -- Diseases -- Genetic aspects. Medical Term Receptors, G-Protein-Coupled -- genetics.
Single-nucleotide polymorphisms (SNPs), particularly non-synonymous variants, provide opportunities for deciphering pathophysiological protein influence. An ideal group for realizing these opportunities is the GPCR-superfamily. Principles from...
Dartmouth Dissertations

A reciprocal relationship between Scavenger Receptor-A and toll-like receptor 4 in bacterial phagocytosis and endotoxic shock resistance.
Cell receptors. Phagocytosis -- Immunological aspects. Septic shock -- Immunological aspects. Bacterial diseases -- Immunological aspects. Natural immunity. Medical Term Receptors, Cell Surface -- physiology. Toll-Like Receptors -- physiology.
An organism's long-term survival is critically dependent on its ability to protect itself from pathogenic microbial infections. The first line of defense against such infections is the branch of the immune response referred to as the innate immune...
Dartmouth Dissertations

Understanding the vulnerabilities of tumors : a network-based approach to drug target discovery / by Nadia M. Penrod.
The demand for novel molecularly targeted drugs will continue to rise as we make progress toward personalizing cancer treatments to the molecular signatures of individual tumors. While the collection and analysis of genomic data has become routine,...
Dartmouth Dissertations

Advancement of magnetic resonance poroelastography for applications in brain imaging / by Adam J. Pattison.
Brain tissue mechanics are an important biomarker for neurological disorders, yet methods to obtain tissue information yield inconsistent conclusions. These techniques can be invasive or require excised tissue, where tissue function is altered from...
Dartmouth Dissertations

Estradiol regulation of innate immune protection in the human female reproductive tract / by Mickey Vinay Patel.
Estradiol is a key regulator of immune protection in the female reproductive tract (FRT). Its concentration varies during the menstrual cycle, leading to changes in innate immune protection. In this thesis, I demonstrate the multiple levels at...
Dartmouth Dissertations

Rejuvenation of cohesion during meiotic prophase is required for maintenance of chiasmata and accurate chromosome segregation / by Katherine Adalia Weng.
Accurate chromosome segregation in human oocytes requires that meiotic sister chromatid cohesion remain intact for decades and work in model organisms indicates that deterioration of meiotic cohesion over time may be a major determinant of...
Dartmouth Dissertations

Endogenous leukocyte activation by chimeric antigen receptor T cell immunotherapy / by Paul Spear.
Many protocols for adoptive T cell therapy (ACT) include preparative conditioning strategies to deplete host lymphocytes prior to T cell infusion. Total body irradiation and high-dose chemotherapy regimens not only relieve immunosuppression, but...
Dartmouth Dissertations

Laying a solid foundation for Manhattan : 'setting the functional basis for the post-GWAS era' / by Xiaoyang Zhang
Genome-wide association studies (GWAS) have identified more than 8,900 genetic variants, mainly single nucleotide polymorphisms (SNPs), associated with hundreds of human traits and diseases, which define risk-associated loci (Hindorff et al., 2012 ...
Dartmouth Dissertations

Alterations in the production of bacteriochlorophyll a and okenone in purple sulfur bacteria : implications for the interpretaion of their biomarkers / by Derek A. Smith.
Purple sulfur bacteria (PSB) can dominate the nitrogen, carbon, and sulfur cycles in anoxic ecosystems via their anoxygenic photosynthetic metabolisms and are the only producers of the carotenoid, okenone, a biomarker targeted for photic zone...
Dartmouth Dissertations

The evolution of mate recognition in Oecanthus tree crickets / by Laurel Symes.
Many organisms recognize and respond to categories: predator, prey, rival, or juvenile. Organisms recognize these ecologically-important categories by assessing diverse sensory stimuli. A primary focus of my research has been understanding how...
Dartmouth Dissertations

Security-policy analysis with eXtended unix tools / by Gabriel A. Weaver.
During our fieldwork with real-world organizations---including those in Public Key Infrastructure (PKI), network configuration management, and the electrical power grid---we repeatedly noticed that security policies and related security artifacts...
Dartmouth Dissertations

Chemico-physical and pharmacologic factors that influence delivery of IONPs to tumors in rodent breast cancer models / by Jennifer Tate.
Nanoparticles have made significant advances in recent years in the realm of cancer therapy. These nanoparticles typically range in size from 10-250nm in diameter, allowing for differential systemic-based biodistribution. The enhanced permeability...
Dartmouth Dissertations

The ecology and bioenergetics of the northern black-throated blue warbler.
Wood warblers.
Dartmouth Dissertations

The representation of size information in semantic memory.
Memory. Size perception. Semantics.
Dartmouth Dissertations

Synthetic studies on sarpagine alkaloids.
Alkaloids. Organic compounds -- Synthesis.
Dartmouth Dissertations

Physical disability and the attribution dilemma : perceiving the causes of behavior in social interaction
People with disabilities -- Psychology; Social perception
Dartmouth Dissertations

Group 6B metal complexes of three and four membered organic rings.
Organometallic compounds. Transition metal compounds.
Dartmouth Dissertations

Examining auroral downward current region processes using ground based data.
Auroras -- Alaska -- Observations. Magnetospheric currents.
This thesis presents data from ground camera observations of the aurora conducted from Alaska during the winters of 2005 through 2007. In conjunction with these camera observations, conjugate radar observations of the auroral ionosphere were...
Dartmouth Dissertations