Spectral theory is the subfield of differential geometry which provided the solution to Kac''s famous question, "Can you hear the shape of a drum?" That is, can we use the Laplace spectrum of a manifold to draw conclusions about its geometry or...
Developmental prosopagnosia (DP) is a neurodevelopmental disorder defined by impaired face recognition in the absence of brain damage, low-level visual deficits, or broad cognitive problems. Behavioral and neural findings suggest different types of...
Cataclysmic variable stars (CVs) are close, interacting binary systems comprised of a white dwarf and a companion star, which is typically a late-type dwarf star. Their progenitor systems are post common envelope binaries (PCEBs) with a white dwarf...
Acyl-CoA:Cholesterol Acyltransferases (ACATs) are key enzymes in cellular cholesterol metabolism. ACAT converts free cholesterol to cholesterol ester, which makes it more easily storable in lipid droplets. There are two ACAT genes encoding two...
Space perception. ; Motion perception (Vision). ; Vestibular apparatus.
Head Direction (HD) cells are neurons located primarily in the limbic system that fire as a function of directional heading in the horizontal, or yaw, plane in the freely moving animal. Our hypothesis is that the HD signal is the result of two...
Hand -- Psychophysiology. Conditioned response. Hand -- Movements. Perceptual-motor processes.
The present studies examine the flexible application of two stimulus-response (SR) mappings to a single set of stimuli. The following questions are addressed: (1) Can dual mapping performance equal single mapping performance (2) Can rapid map...
Nerve growth factor (NGF), the prototypic neurotrophin, is well characterized for its pro-survival and growth effects in sympathetic and sensory neurons. Acting as a target-derived factor, NGF regulates the maturation of innervating neurons, and...
The auroral zone is a rich source of natural radio emissions that can be observed in space and at ground-level. By studying these waves, scientists can gain insight into the plasma processes that generate them and use the near-Earth space...
Visual searches for a conjunction of features (e.g., a particular combination of color and shape) are ordinarily slow and difficult. However, search efficiency for a particular conjunction can improve dramatically within a few hundred practice...
Two experiments were designed to investigate the effects of brain damage on source monitoring. Source monitoring is the process of making decisions about the origins of memories. Previous research has demonstrated that source monitoring judgments...
Face perception -- Physiological aspects. Face perception -- Social aspects. Sex differences (Psychology). Neuropsychology.
The general objective of the current thesis was to investigate the neural substrates underlying the perception of opposite-sex faces. Building on what is already known about the distributed network of brain areas supporting various dimensions of...
Does early and sustained experience with two languages in childhood modify how language is processed in the adult bilingual brain? Does extensive exposure to two languages influence language processing in the bilingual brain as compared to...
Multimodality imaging is becoming the standard of care for research and clinical studies. Such an approach is able to provide complementary information which can detect and characterize tumors. Advancing instrumentation for diffuse near-infrared...
Humans have a seemingly unique capacity to reflect upon information about the self to form evaluative attitudes that influence their quality of life and predict mental health outcomes. While psychologists have devoted decades of research to the...
The ionosphere is the primary source for heavy ions which are ubiquitous in the terrestrial magnetosphere. Low-altitude energization in the auroral ionosphere results in bulk heating and transverse acceleration of ions, which begin to upwell and/or...
Neuroanatomical studies have defined two relatively separate corticohippocampal processing streams that contribute substantially to medial temporal lobe function. Among the cortical regions providing significant input to these processing streams is...
Corpus callosum -- Physiology. Cerebral hemispheres. Laterality. Sensorimotor integration. Brain -- Localization of functions.
The overarching goal of the dissertation was to further understanding of the relationship between callosal organization, functional lateralization, and interhemispheric communication in the healthy, young adult brain. Three converging methodologies...
Gaze -- Psychological aspects. ; Facial expression. ; Body language.
The primary goal of the current research was to examine the effect of perceived gaze direction on the perception and processing of facially communicated emotion. There is good reason to believe that gaze direction and facial displays of emotion...
Robots -- Control systems. ; Robots -- Motion. ; Computer algorithms. ; Electronic data processing -- Distributed processing.
Self-reconfiguring robots are robots composed of many physically connected modules which can change their structural configuration to support multiple functionalities. We claim that self-reconfiguring robots are more versatile, extensible, and...
Electric fields in the high-latitude regions of Earth's ionosphere are an important component of the coupled magnetosphere-ionosphere-thermosphere system. Characterizing the average behavior of these fields (or the corresponding drifts) is useful...
Form perception. ; Visual perception. ; Motion perception (Vision). ; Color vision. ; Visual cortex -- Psychophysiology.
Visual filling-in occurs when a retinally stabilized object undergoes perceptual fading. It is commonly believed that information about the apparently vanished object is lost and replaced solely by information arising from the surrounding...
The ionosphere is an important source of plasma in the magnetosphere, especially during geomagnetic storms. While satellite data has confirmed this population of ions, their effect on the dynamics of the magnetosphere-ionosphere (MI) system is not...
Optical tomography. Fluorescence. Imaging systems -- Design and construction. Diagnostic imaging -- Mathematical models. Brain -- Diseases -- Diagnosis. Brain -- Magnetic resonance imaging.
Fluorescent molecules targeted to reveal information on tissue function have been used as research tools in ex vivo and subsurface characterization of diseased tissue for years. Exploiting this specificity for in vivo imaging through centimeters of...
Continual improvements to clinical breast imaging technologies have led to ever earlier detections and increasingly accurate localizations of female breast cancers. While these advancements have certainly improved the prognoses of many patients,...
As the visual effect and movie industries are striving for realism and high fidelity images, physically based lighting, global illumination, realistic materials, and highly tessellated geometry are gradually accepted and used in movie and game...
Purple sulfur bacteria (PSB) can dominate the nitrogen, carbon, and sulfur cycles in anoxic ecosystems via their anoxygenic photosynthetic metabolisms and are the only producers of the carotenoid, okenone, a biomarker targeted for photic zone...
Traumatic brain injury (TBI) is the leading cause of acquired disability in children, yet innate repair mechanisms are incompletely understood. A possible innate mechanism to repair injury after insult is neurogenesis - the birth, migration,...
Molecular optical imaging in vivo has potential for functional assessment of tumor tissue at the cellular and subcellular level. Advances in biological understanding of genomics and proteomics have increased the knowledge of possible cellular...
We present new forensic tools that are capable of detecting traces of tampering in digital images without the use of watermarks or specialized hardware. These tools operate under the assumption that images contain natural properties from a variety...
The processes affecting gas transport through the firn column are important to understand in order to accurately interpret climate records from ice cores. Historically, density measurements have been used to estimate open and closed porosity in the...
After decades of searching we have yet to find the progenitor systems for type Ia supernovae. In fact most of what we know about this homogeneous class of supernovae is from spectral features associated with the incinerated remains of the C+O white...
While anthropogenic emissions of the toxic element mercury (Hg) to the atmosphere are currently rising, major uncertainties remain in determining the relative impacts of anthropogenic activity and natural processes on the global Hg cycle. In this...
Fluorescence molecular imaging will have an important clinical impact in the area of guided oncology surgery, where emerging technologies are poised to provide the surgeon with real-time molecular information to guide resection, using targeted...
This project focuses on the development of research tools and methods that are used to study the relationship between neural activity and subsequent hemodynamic responses in the human brain. This relationship, referred to as neurovascular coupling,...
Epilepsy is associated with cognitive impairments which often manifest as a higher prevalence of memory impairments. Memory impairments in patients with epilepsy may persist even with sufficient control of seizures, suggesting other factors may...
The overarching goal of this thesis was two-fold. First, to determine if the effects of chronic anabolic androgenic steroid (AAS) treatment on anxiety-like behaviors are sex-specific and second to determine how different environmental modulators...
The Greenland Ice Sheet (GrIS) is responding sensitively to climate change and its meltwater has the potential to influence global sea level. Recently, large changes in the GrIS have occurred including increased velocities of outlet glaciers and...